This technology is a mouse model engineered to conditionally delete the autophagy-linked FYVE protein WDFY3, creating an effective research tool for studying autophagy, mitophagy, efferocytosis, ...
This technology is a conditional human ALFY protein-expressing mouse model for the study of diseases driven by pathological protein aggregation in the nervous system.
This technology describes a distinct class of ibogaine analogs created by chemical synthesis that maintains the pharmacological benefits of ibogaine with reduced cardiac adverse effects.
This technology is a nucleotide sequence for amplifying the expression of WDFY3 gene or its encoded protein, Autophagy-Linked FYVE (ALFY), that can be used to promote protein aggregate clearance ...
This technology is a mechanism for treating brain disorders resulting from Group A Streptococcus infection including encephalitis by targeting a serum cytokine biomarker IL-17A.
This technology is NeuroScore AI, an automated AI program that can be used to calculate Alzheimer’s Disease risk score by transcribing audio files from standardized cognitive testing.
This technology is a hybrid configuration of multi-coils and radiofrequency magnets that can improve clinical magnetic resonance imaging (MRI) quality.
This technology is a dual-head MRI system equipped with local shimming capabilities for simultaneous functional imaging of two adjacent subjects, facilitating the study of interpersonal ...
This technology is a method of using metabolic profiling-related biomarkers to identify newborns or infants with autism spectrum disorder for early intervention.
This technology is an in vivo tool using focused ultrasound (FUS) with microbubbles to induce blood-brain barrier opening (BBBO) and increase serum extracellular vesicle (EV) levels.
This technology includes two chemical compounds that are phosphodiesterase type 5 (PDE5) inhibitors with a benzonaphthyridine derivative chemical scaffold that has not previously been used to ...