Columbia Technology Ventures

Immunology & Inflammation

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Glycolipids and analogues as antigens for natural killer T cells
This technology describes the development of immunogenic compounds to serve as ligands for natural killer T cells to modulate immune responses.
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Adjuvant therapyAntigenCytokine
David Da-i Ho M.D.Moriya Tsuji
Kristin Neuman
MedicinePhysicians & Surgeons
Columbia University Medical Center (CUMC)
2022-07-21
Human protective antibodies for use against H7N9 influenza virus
This technology describes human monoclonal antibodies derived from the B cells of a case of zoonotic avian influenza virus H7N9 to treat or prevent H7N9 infections.
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Antiviral drugAvian influenzaB cell
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David Da-i Ho M.D.Kelvin Kai-Wang ToKwok-Yung Yuen
Kristin Neuman
5
Aaron Diamond AIDS Research Center (ADARC)Dept. of Biochemistry and Molecular Biophysics / OphthalmologyMedicine
Columbia University Medical Center (CUMC)
2024-07-18
Antibody-like molecule for specific and potent HIV latency reversal
This technology is a method to target and eliminate the viral reservoir of latent HIV-1 using latency reversal agents facilitated by targeted delivery with monoclonal antibodies.
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Antiviral drugCD4Combination therapy
5
David Da-i Ho M.D.Hiroshi MohriJian Yu
Kristin Neuman
Aaron Diamond AIDS Research Center (ADARC)Medicine
Columbia University Medical Center (CUMC)
2024-10-25
Targeting NTPDase8 for treating liver ischemia
This technology identifies the nucleoside triphosphate diphosphohydrolases 8 (NTPDase8) as a therapeutic target for liver ischemia-reperfusion injury.
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AllotransplantationBleedingEpistasis
George HaskoTaha Kelestemur
Kristin Neuman
Anesthesiology
Columbia University Medical Center (CUMC)
2025-10-16
Targeted pharmacological agents for the prevention of multiple organ failure in hemorrhagic shock patients
This technology is a pharmacological intervention targeting localized inflammatory responses in trauma and hemorrhagic shock to prevent multiple organ failure.
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AdenosineAdenosine receptorAgent-based model
George HaskoTaha Kelestemur
Kristin Neuman
Anesthesiology
Columbia University Medical Center (CUMC)
2024-04-25
Purine receptor blockade for treating hemorrhagic shock
This technology is a P2X4 or P2X7 purine receptor-targeted therapy for the treatment of shock-induced multiple organ failure.
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Chronic painHypovolemiaInflammation
George HaskoTaha Kelestemur
Kristin Neuman
Anesthesiology
Columbia University Medical Center (CUMC)
2025-08-19