This technology is a method for manufacturing nanofiber scaffolds for use in tendon transection repair procedures.
Tendon transection injuries heal extremely slowly and patients may never regain full function. Current surgical approaches to tendon repair involve the use of synthetic or biological supports, which are prone to complications due to unguided scar-filled healing. Furthermore, these materials have poor mechanical properties, fail to mimic natural tendon morphology, and are subject to rapid graft remodeling under physiological stress.
This technology is a fabrication method for manufacturing gelatin polymer nanofiber scaffolds. Unlike existing technologies, these scaffolds directly mimic the 3D substructure of tendons. In vitro results using a tendon transection research model demonstrate that host cells can successfully proliferate around the scaffold. Importantly, this enables host cells to successfully proliferate around the scaffold in a guided fashion that minimizes scar tissue formation. As such, this technology has the potential to improve tendon regeneration and thereby shorten recovery after tendon resection injuries.
Patent Pending
IR CU19257
Licensing Contact: Joan Martinez