Advanced laser fluorometry platform for real-time biological analysis

This technology is a portable fluorescence-based sensing platform for real-time detection, measurement and monitoring of biological and environmental samples.

Unmet Need: Mobile fluorescence sensing platform for biological monitoring

Current methods for detecting and quantifying biological molecules often require expensive laboratory equipment, time-consuming sample preparation, and specialized expertise. These limitations can make it difficult to obtain rapid, high-quality measurements in field, aquatic, or resource-limited environments. There is a need for accessible, portable technologies that enable real-time characterization of biological materials while maintaining the sensitivity and accuracy of laboratory-based approaches.

The Technology: Portable fluorometry platform for rapid biological analysis

This technology is a portable laser fluorometry platform that enables rapid, high-resolution analysis of biological and environmental samples through spectral analysis. By separating complex fluorescence signals into their individual components, the platform can identify and quantify fluorescent constituents while providing deeper insight into sample composition and biological activity. Its portable design supports real-time measurements in both laboratory and field settings.

This platform has been used for the analysis of chlorophyll, phycobiliproteins, dissolved organic matter, and other fluorescent constituents in liquid samples.

Applications:

• Environmental monitoring and sensing
• Water quality analysis
• Industrial process monitoring
• Portable field testing and equipment
• Chemical and biological sensing
• Agricultural and food systems monitoring
• Life science research tool
• Ecological and marine research

Advantages:

• Portable and field-deployable
• Provides both spectral and temporal fluorescence
• Improves sensitivity and specificity for fluorescent constituent detection
• Supports real-time analysis and monitoring
• Versatile platform adaptable to multiple applications
• Reduces need for manual data interpretation through automated analysis

Lead Inventor:

Alexander Chekalyuk, Ph.D.

Patent Information:

Patent Issued(US 89,708,41)

Related Publications:

• Chekalyuk A, Hafez M. “Next generation Advanced Laser Fluorometry (ALF) for characterization of natural aquatic environments: new instruments” Opt Express. 2013 Jun 17;21(12):14181-201.

• Chekalyuk A, Barnard A, Quigg A, Hafez M, Zhao Y. “Aquatic laser fluorescence analyzer: field evaluation in the northern Gulf of Mexico” Opt Express. 2014 Sep 8;22(18):21641-56.

Tech Ventures Reference:

• IR M10-049

• Licensing Contact: Dovina Qu