Columbia Technology Ventures

Antibacterial wound dressings, First Aid Topical cream Band Aids, soap and disinfects with long-lasting activity against both gram-negative and gram-positive bacteria

This technology is a multifaceted topical wound treatment for antibacterial wound dressings, first aid topical creams and band aid. Antibacterial components in this composition can permeate into the upper layers of the skin to generate a lasting antimicrobial effect.

Unmet Need: Effective combined antimicrobial wound creams

Conventional antimicrobial disinfectants for topical applications are commonly used in a wide variety of patient care scenarios and used to both treat wounds and prevent infection. They can also be utilized to dress bandages for both hospital and at-home (e.g., Band-Aid) applications. Unfortunately, the conventionally used disinfectants are environmentally-unfriendly, serve as skin irritants, and do not prevent the reproliferating of pathogens after application due to low skin permeability. Additionally, wound treatment compounds and disinfectants are generally sold separately, making their application complex and oftentimes cumbersome.

The Technology: Antibacterial formulations permeate into the upper layers of the skin to generate a lasting antimicrobial effect

This technology is a tandem system of antimicrobial and wound healing compounds which can be applied topically and also used to dress bandages for both professional and at-home applications. The antibacterial and antimicrobial constituents are advantageous as they can penetrate the skin to allow for long-acting effects to prevent the regrowth of pathogens. Moreover, use of this formulation along with over the counter anti-bacterial and antifungal agents such as Neosporin, Benzalkonium chloride, Miconazole etc. synergistically enhances the antimicrobial efficacy as well as promote wound healing.

The technology was experimentally confirmed on the hands of human volunteers as well as with an in vitro pig skin model. The results demonstrated that the formulation efficiently reduces the activity of both gram-negative (E. coli) and gram-positive (S. aureus) bacteria for up to an hour after use.

Applications:

  • Antimicrobial dressing for surgical scrubs and supplies
  • Dressing for over the counter bandages
  • Antimicrobial soap and topical skin cleansers
  • Medical device sterilization

Advantages:

  • Deeper skin permeation for more effective antimicrobial properties
  • Lower human toxicity
  • Tandem wound healing and antimicrobial characteristics

Lead Inventor:

Shanta M. Modak, Ph.D.

Patent Information:

Patent Pending (US 20140243417)

Patent Pending (EP 2773334)

Patent Pending (WO/2013/067150)

Related Publications:

Tech Ventures Reference:

  • IR CU12338, CU12158, 2976

  • Licensing Contact: Sara Gusik