{"id":"CU22384","slug":"augmented-ultrasonography-with--CU22384","source":{"id":"CU22384","dataset":"techtransfer","title":"Augmented ultrasonography with implanted CMOS electronic motes","description_":"<p>This technology is an advanced medical imaging system that uses implanted, battery-less CMOS motes to enhance ultrasound diagnostics and monitoring.</p>\r\r<h2>Unmet Need: Ultrasonography method for improved imaging with low power configurations</h2>\r\r<p>While conventional ultrasonography is the gold standard in non-invasive medical imaging, it faces limitations in consistently generating reliable, high-resolution images, especially at low power settings. This shortcoming restricts its efficacy in continuous or real-time monitoring of internal body structures and the functioning of implanted medical devices. Addressing these limitations is crucial, as it can significantly enhance diagnostic accuracy, enable continuous health monitoring, and improve the management of various medical conditions. </p>\r\r<h2>The Technology: Wireless implantable motes that can locate, track, and power an ultrasound image in real-time</h2>\r\r<p>This technology leverages CMOS electronic motes implanted in the body to augment ultrasonography imaging. These battery-less devices, positioned within the ultrasound field-of-view, enhance image resolution and consistency, especially at low power settings. The motes operate on extremely low energy levels, ensuring physiological safety and minimal tissue impact. This technology can be expanded to multiple ultrasound-responsive implantable devices to enhance tracking and transmission of device data. </p>\r\r<p>This technology has been validated <i>in vivo </i>. </p>\r\r<h2>Applications:</h2>\r\r<ul>\r<li>Enhanced reliability for diagnoses using ultrasonography</li>\r<li>Remote, wireless tracking of implantable devices</li>\r<li>CMOS imaging sensors for security and surveillance</li>\r</ul>\r\r<h2>Advantages:</h2>\r\r<ul>\r<li>Improved resolution of ultrasound images</li>\r<li>Continuous and real time monitoring</li>\r<li>Non-invasive approach for long-term monitoring</li>\r<li>Can support transmission from multiple implantable devices</li>\r</ul>\r\r<h2>Lead Inventor:</h2>\r\r<p><a href=\"https://www.engineering.columbia.edu/faculty/ken-shepard\">Kenneth L. Shepard, Ph. D.</a></p>\r\r<h2>Patent Information:</h2>\r\r<p>Patent Pending (US<a href=\"https://patents.google.com/patent/US20250120671A1/\">20250120671</a>)</p>\r\r<h2>Related Publications:</h2>\r\r<ul>\r<li><a href=\"https://pubmed.ncbi.nlm.nih.gov/35725979/\">Zhang Y, Muthuraman P, Andino-Pavlovsky V, Uguz I, Elloian J, Shepard KL. “Augmented ultrasonography with implanted CMOS electronic motes” Nat Commun. 2022 Jun 20; 13(1):3521.</a></li>\r</ul>\r\r<h2>Tech Ventures Reference:</h2>\r\r<ul>\r<li><p>IR CU22384</p></li>\r<li><p>Licensing Contact: <a href=\"mailto:techtransfer@columbia.edu\">Greg Maskel</a> </p></li>\r</ul>\r","tags":["CMOS","Energy","Image resolution","Medical imaging","Wireless"],"file_number":"CU22384","collections":[],"meta_description":"Implantable, battery-less CMOS motes boost ultrasound imaging: higher resolution, real-time tracking with low power, safer continuous monitoring.","apriori_judge_output":"{\"scores\":{\"novelty\":4.0,\"potential_impact\":4.0,\"readiness\":4.0,\"scalability\":3.0,\"timeliness\":2.0},\"weighted_score\":3.48,\"risks\":[\"Clinical adoption risk\",\"regulatory clearance timeline\",\"implant-related safety monitoring complexity\",\"manufacturing/implantation workflow integration\",\"data security/privacy concerns\"],\"one_sentence_take\":\"High novelty with meaningful impact but longer regulatory/clinical adoption trajectory and modest scalability depending on implant logistics.\"}","inventors":["Ilke Uguz","Jeffrey Elloian","Kenneth Shepard","Prashant Muthuraman","Victoria Andino Andino-Pavlovsky","Yihan Zhang"],"manager":"Greg Maskel","depts":["Electrical Engineering"],"divs":["Fu Foundation School of Engineering and Applied Science (SEAS)"],"date_released":"2026-10-09"},"highlight":{},"matched_queries":null,"score":0.0}