Collagen wrap for ligament repair
This technology is a collagen wrap that promotes anterior cruciate ligament (ACL) healing by protecting the wound from negative synovial fluid factors while still allowing nutrients to diffuse through.
Unmet Need: Treatment for ligament wounds that modulate the biochemical environment
The current standard of care for treating torn anterior cruciate ligaments (ACLs) is surgical grafts, which primarily provide mechanical stabilization. However, these grafts lack control over the synovial fluid and do not address the biochemical environment at the injury site that prevents true tissue regeneration. Currently, there are no treatments that help modulate the local wound healing environment.
The Technology: Collagen wrap that promotes biochemical healing of ligaments
This technology is a sheet-like wrap made of collagen that protects the wounded anterior cruciate ligament (ACL) and promotes healing. The wrap blocks negative biochemical factors found in the synovial fluid from entering the wound site, while still allowing critical nutrients to permeate, thereby modulating the local biochemical environment of the wound. It also enables other drugs and therapeutic agents to be delivered to the repair site.
Applications:
- Accelerated anterior cruciate ligament (ACL) repair
- Ligament repair at multiple joints, such as the knee, ankle, and shoulder
- Research tool for studying tissue repair mechanics
Advantages:
- Creates a local healing microenvironment
- Blocks negative synovial fluid factors from entering
- Enables sustained drug delivery to wound site
- Can be cellular or acellular
Lead Inventor:
Patent Information:
Patent Pending
Related Publications:
Tech Ventures Reference:
IR CU20196, CU25026
Licensing Contact: Dovina Qu