Configurable Kalman filtering for brain-computer interfaces

This technology is a configurable, energy-efficient Kalman filtering platform for real-time motion prediction in brain-computer interfaces.

Unmet Need: Low-power real-time processing of neural data

Current brain-computer interfaces (BCI) rely on computational methods that prioritize decoding accuracy and often assume access to abundant power, memory, and delay-tolerant hardware. As neural interfaces scale to higher electrode counts and larger neural datasets, these assumptions break down, limiting real-time performance, mobility, and long-term implantability. Existing signal estimation methods are not well-suited to the constraints of embedded BCI systems, where power consumption, latency, and adaptability must be balanced. Addressing these limitations is essential to enable practical, real-world BCIs that can operate continuously and reliably outside of research environments.

The Technology: Energy-efficient embedded real-time neural decoding

This technology enables real-time neural decoding by implementing state-based interference methods within a configurable embedded architecture designed to operate under strict power and latency constraints. Neural signals are processed sequentially using predictive models that combine incoming measurements with prior system states to continuously estimate control or motion intent. The system leverages spatiotemporal correlations in neural data to reduce computational load while maintaining decoding performance, and supports runtime adjustments of accuracy, latency, and energy trade-offs for various BCI applications.

This technology has been validated through FPGA-based prototyping, demonstrating improved energy efficiency and real-time performance on high-dimensional neural datasets.

Applications:

  • Brain-computer interfaces for assistive motor control (prosthetics, exoskeletons, communication devices)
  • Implantable and wearable interfaces for long-term monitoring
  • Neurorehabilitation and neuromodulation systems
  • Neural decoding frameworks for algorithm development
  • Embedded neural signal processing platforms for research and clinical BCI development
  • Training and education tool for rehabilitation with real-time feedback

Advantages:

  • Real-time neural decoding
  • Energy-efficient operation
  • Adaptable to different BCI applications and datasets
  • Scalable to high-dimensional neural signals
  • Compatible with low-power, resource-constrained hardware
  • Enables continuous real-time operation

Lead Inventor:

Luca P. Carloni, Ph.D.

Patent Information:

Patent Pending

Tech Ventures Reference:

Quick Facts:
Tags
AlgorithmData communicationElectrodeEnergyKalman filterLow-power electronicsMotor controlNeuromodulation
Inventors
Guy EichlerJoseph ZuckermanLuca Carloni
Manager
Greg Maskel
Departments
Computer Science
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Reference Number
CU25167
Release Date
2026-01-16