This technology is a mechanical cardiac valve prosthesis capable of expanding over time to meet with the demands of a young heart proceeding through development.
Of the two main types of valves currently used, mechanical heart valves tend to be superior in durability compared to bioprosthetic versions. However, mechanical valves lead to a high risk of thrombus formation, requiring patients to take anticoagulants throughout life. Furthermore, pediatric patients outgrow implants during the course of development and often require additional operations. There remains to be seen a durable yet low-risk cardiac valve prosthesis compatible with the biology of a developing heart.
The device is comprised of a non-biodegradable, microfluidic membrane that allows for unidirectional flow, housed within a biodegradable tube. The design is such that, as a child grows, the tube degrades and allows the membrane to expand, reducing the need for reoperation. Furthermore, the membrane does not disrupt blood flow, which could reduce the risk of thrombosis and the need for a lifetime anticoagulant. As such, this technology provides an improved mechanical cardiac valve that is compatible with young, developing hearts.
Patent Pending
IR CU17154
Licensing Contact: Ron Katz