This technology is a momentum tracking device that can be used to measure and distinguish tremor from voluntary motion in animal models of movement disorders.
Detecting action tremor requires high-resolution measurement of motion kinetics to discriminate between tremor and voluntary movement. Current methods for detecting action tremor rely on video-based and accelerometer-based methods which are limited by spatiotemporal resolution and therefore lack the sensitivity to detect action tremor preceding essential tremor.
This device detects overall momentum and tremor in rodent models by recording intrinsic oscillations through a force plate. The force plate accommodates a free-moving mouse whose kinematic motion shifts the force plate resulting in data transformation into a voltage output. Measuring the magnitude and frequency of the signal allows simultaneous tracking of both overall motion and tremor.
This technology has been validated with a mouse model of essential tremor.
Patent Pending
IR CU22120
Licensing Contact: Jerry Kokoshka