Technologies
This technology is a platform for noninvasive brain stimulation using focused ultrasound waves for brain mapping and therapeutic applications.
Current neuromodulation approaches for the treatment of neurological disorders often rely on invasive procedures or lack spatial precision needed to specifically target deep brain structures. While focused ultrasound has emerged as a noninvasive approach for targeting these deep brain structures, many existing systems lack integrated platforms capable of delivering precise stimulation while simultaneously tracking physiological and behavioral responses. In addition, limited control over stimulation parameters and monitoring outputs can make it difficult to optimize treatment delivery, assess patient response, and personalize neuromodulation strategies.
This technology is a focused ultrasound transducer platform designed to noninvasively deliver acoustic energy to targeted brain structures and the peripheral nerve circuits. Using focused ultrasound waves for brain stimulation, the system integrates software capable of encoding and monitoring multiple parameters, including vital signs and eye movements, during neuromodulation without surgical implantation. The platform enables modulation of neural activity and can be integrated with imaging and electrophysiological systems for feedback-guided targeting and stimulation. This technology has potential applications in neuroscience and treatment of disorders such as chronic pain and Parkinson’s disease.
This technology has been validated in mouse models.
Patent Issued(US15/040926)
Patent Issued(US16/265,827)
IR CU15132, CU17014
Licensing Contact: Dovina Qu