NON-EXCLUSIVE EVALUATION OF PROTOTYPE LICENSE AGREEMENT {{ technology.fileNumber }}

This AGREEMENT is dated ________________, 20__ (the "Effective Date") and is, between THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, a New York corporation ("Columbia"), and {{ licensee.organization }}
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{{ licensee.city }}, {{ licensee.state }}, {{ licensee.country }} {{ licensee.zipCode }} ("Company").

Definitions. For purposes of this Agreement, the following definitions apply:

a. "Affiliate" means any corporation or other entity that, as of the Effective Date, directly or indirectly controls, is controlled by, or is under common control with, another corporation or entity. Control means direct or indirect ownership of, or other beneficial interest in, fifty percent (50%) or more of the voting stock, other voting interest, or income of a corporation or other entity.

b. "Cover" or "Covered By" means (i) infringes, in the case of a claim in an issued patent, or (ii) would infringe the claim if it existed in an issued patent, in the case of a claim in a pending application.

c. "Designee" means a corporation or other entity that is employed by, under contract to, or in partnership with Company wherein such corporation or other entity is granted the right to make Products.

d. "Materials" means the tangible physical material, if any, delivered to Company hereunder. Any Materials delivered to Company hereunder will be provided to Company via hyperlinks after execution of this Agreement .

e. "Patent" or "Patents" means the following: (i) the United States and foreign patents and/or patent applications listed in Exhibit A to this Agreement; (ii) any non-provisional patent applications that claim priority to any provisional patent applications listed in Exhibit A to this Agreement; (iii) any claims of continuation-in-part applications that claim priority to the United States patent applications listed in Exhibit A, but only where such claims are directed to inventions disclosed in the manner provided in the first paragraph of 35 U.S.C. Section 112 in the United States patent applications listed in Exhibit A, and such claims in any patents issuing from such continuation-in-part applications; (iv) any rights corresponding to the foregoing in foreign patent applications, foreign patents or related foreign patent documents that claim priority to the patents and/or patent applications listed in Exhibit A; (v) any divisionals, continuations, reissues, re-examinations, renewals, substitutions, and extensions of the foregoing; and (vi) any patents issuing from the foregoing. Notwithstanding the preceding definition, Patent and Patents will not include any patents or patent applications based on research conducted after the Effective Date, except as otherwise agreed in a separate writing.

f. "Product" or "Products" means the product (i) Covered By the Patents, and/or (ii) that uses or incorporates, in whole or in part, the Technical Information or Materials.

g. "Technical Information" means Columbia's property interest in any know-how, technical information, and data which was each of the following: (i) developed by Columbia by or under the direction of Dr. Yevgeniy Yesilevkiy, Keith Yeager, Jeffery Kysar, Anil Lalwani, Elizabeth Hillman, Jake Lee, and Shelby Arnold, (ii) developed before the Effective Date, (iii) provided to or received by Company, and (iv) necessary or useful for the discovery, development, manufacture, use, sale, offering for sale, importation, exportation, distribution, rental or lease of a Product.

Technical Information includes, but is not limited to, the following: (i) any know-how, technical information, and data disclosed in any Patent; (ii) any reports or disclosures concerning research or inventions provided or disclosed to, or otherwise received by, Company; and (iii) any information in Exhibit B to this Agreement.

h. "Third Party" means any entity or person other than Company, Designees, or their Affiliates.

1. License Grant.

a. Grant. Columbia grants to Company, upon and subject to all the terms and conditions of this Agreement:

(i) a non-exclusive, no-cost license under the Patents to evaluate, manufacture, have made, and use Products;

(ii) a non-exclusive, no-cost license to use Technical Information to evaluate, manufacture, have made, and use Products; and

(iii) a non-exclusive, no-cost license to use Materials to evaluate, manufacture, have made, and use Products.

b. Government Rights. All rights and licenses granted by Columbia to Company under this Agreement are subject to (i) any limitations imposed by the terms of any government grant, government contract or government cooperative agreement applicable to the technology that is the subject of this Agreement and (ii) applicable requirements of 35 U.S.C. Sections 200 et seq., as amended, and implementing regulations and policies.

c. Reservation. All rights not specifically granted herein are reserved to Columbia. Except as expressly provided under this Section 2, no right or license is granted (expressly or by implication or estoppel) by Columbia to Company or its Affiliates under any tangible or intellectual property, materials, patent, patent application, trademark, copyright, trade secret, know-how, technical information, data or other proprietary rights.

d. Improvements. Columbia shall own all improvements and modifications of the Product (collectively, "Improvements"), including those resulting from the input, feedback, or suggestions related to the Product (including, without limitation, design improvements) which Company may provide under Section 3a ("Feedback").

2. Feedback on the Products.

a. Company may provide Feedback on the Products. Company will endeavor, during the term of the Agreement, to provide design feedback on the Products to techventures@columbia.edu. Such Feedback may be provided by Company in oral or written form. Any Improvements to the Patents, Technical Information, Materials or Products based on such Feedback, will be automatically included within the licenses granted to Company under Section 2a.

3. Confidentiality.

a. Confidential Information. Except to the extent required to evaluate, manufacture, have made, or use Products in the Field, Company will treat as confidential the Patents, Materials, and Technical Information disclosed hereunder, and will not disclose or distribute the same to any third party without Columbia's written permission.

b. Exceptions. The obligations of confidentiality under this Section 4 do not apply to any Patents, Materials, or Technical Information that Company can demonstrate was any of the following: (i) was known to Company before receipt thereof from Columbia; (ii) was or became a matter of public information or publicly available through no act or failure to act on the part of Company; (iii) was acquired by Company from a third party entitled to disclose it to Company; or (iv) was discovered or developed independently by Company without reference to or use of such Patents, Materials, or Technical Information, as evidenced by contemporaneous written records.

c. Defend Trade Secrets Act. Defend Trade Secrets Act. Notwithstanding the foregoing, under 18 U.S.C. §1833(b), "An individual shall not be held criminally or civilly liable under any Federal or State trade secret law for the disclosure of a trade secret that (A) is made (i) in confidence to a Federal, State, or local government official, either directly or indirectly, or to an attorney; and (ii) solely for the purpose of reporting or investigating a suspected violation of law; or (B) is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal." Nothing in this Agreement or any Columbia policy is intended to conflict with this statutory protection, and no Columbia trustee, director, officer, or member of management has the authority to impose any practice to the contrary.

4. Disclaimer of Warranty; Limitations of Liability; Waiver of Claims.

a. Disclaimer. Columbia is licensing the Patents, Materials, Technical Information, and the subject of any other license hereunder, on an "as is" basis. The Products are experimental in nature and their characteristics and performance in the Field is not completely known. Columbia makes no warranties either express or implied of any kind, and hereby expressly disclaims any warranties, representations or guarantees of any kind as to the Patents, Materials, Technical Information, Products and/or anything discovered, developed, manufactured and used under any license granted hereunder, including but not limited to: any warranties of merchantability, title, fitness, adequacy or suitability for a particular purpose, use or result; any warranties as to the validity of any patent; any warranties of freedom from infringement of any domestic or foreign patents, copyrights, trade secrets or other proprietary rights of any party; and any warranties that the Products will perform or comply with federal, state or municipal laws and regulations regarding medical supplies or medical uses.

b. Limits of Liability. Company is solely responsible and solely liable for Company's and its officers, directors, employees, consultants, and agents actions under this Agreement. In no event will Columbia, or its trustees, officers, faculty members, students, employees, and agents, have any liability to Company, Designees, or Affiliates of the foregoing, or any Third Party arising out of the use, operation or application of the Patents, Technical Information, Materials, Products, or anything evaluated, manufactured, and/or used under any license granted hereunder by Company, Designees or Affiliates of the foregoing, or any Third Party for any reason, including but not limited to, the unmerchantability, inadequacy or unsuitability of the Patents, Materials, Technical Information, Products and/or anything evaluated, manufactured, and/or used under any license granted hereunder for any particular purpose or to produce any particular result, or for any latent defects therein.

c. Damages. On the one hand, in no event will Columbia, or their trustees, officers, faculty members, students, employees, and agents, be liable to Company, its Affiliates, Designees, or any Third Party, and on the other hand, in no event shall Company, its Affiliates, and Designees be liable to Columbia or any Third Party, for: any consequential, incidental, special or indirect damages (including, but not limited to, from any destruction to property or from any loss of use, revenue, profit, time or goodwill) based on activity arising out of or related to this Agreement, whether under a claim for breach of contract or any other claim of any type.

d. Waiver of Claims. Company is solely responsible and solely liable for its, and its officers, directors, employees, consultants, and agents actions under this Agreement. Company and its Affiliates, agrees to waive any and all claims against Columbia and its trustees, officers, faculty members, students, employees, and agents, related to any evaluation, making, manufacture or use of the Products, Patents, Technical Information, and Materials by Company under this Agreement. Except with respect to claims to enforce Section 9a, Columbia agrees to waive any and all claims against Company, and its trustees, officers, directors, employees, consultants, and agents related to any evaluation, making, manufacture or use of the Products, Patents, Technical Information, and Materials by Company under this Agreement.

e. Liability Limit. In no event will Columbia's total liability to the Company under this Agreement exceed $500.

f. Essentiality. The parties hereto acknowledge that the limitations and exclusions of liability, disclaimers of warranty, and waiver of claims set forth in this Agreement form an essential basis of the bargain between the parties.

5. Prohibition Against Use of Columbia's Name.

The Company will not use the name, insignia, or symbols of Columbia, its faculties or departments, or any variation or combination thereof, or the name of any trustee, faculty member, another employee, or student of Columbia for any purpose whatsoever without Columbia's prior written consent.

6. Compliance with Governmental Obligations.

a. Regulations. Notwithstanding any provision in this Agreement, Columbia disclaims any obligation or liability arising under the license provisions of this Agreement if Company or its Affiliates is charged in a governmental action for not complying with or fails to comply with governmental regulations in the course of taking steps to bring any Product to a point of practical application.

b. Request. Company and its Affiliates shall comply upon reasonable notice from Columbia with all governmental requests directed to either Columbia or Company or its Affiliates and provide all information and assistance necessary to comply with the governmental requests.

c. Compliance. Company and its Affiliates shall ensure that evaluation, and manufacturing under this Agreement complies with all government regulations in effect including, but not limited to, Federal, state, and municipal legislation.

7. Patent Prosecution and Maintenance; Litigation.

a. Prosecution. Columbia, acting in its sole discretion, by its counsel, will prepare, file, prosecute and maintain all Patents in Columbia's name.

b. Litigation. Columbia will have the sole right to initiate, control, defend and/or settle any proceedings involving the validity, enforceability, or infringement of any Patents when, in its sole judgment, such action may be necessary, proper, and justified.

8. Indemnification and Insurance.

a. Indemnification. The Company shall indemnify, defend, and hold harmless Columbia, its trustees, officers, faculty, employees, students and agents, from and against any and all actions, suits, claims, demands, prosecutions, liabilities, costs, expenses, damages, deficiencies, losses or obligations (including attorneys' fees) arising out of or relating to this Agreement, including, Company's and its Affiliates use of Products, Patents, Materials or Technical Information, and any representation made or warranty given by the Company or its Affiliates with respect to Products. The Company shall reimburse Columbia for the actual fees, costs, and expenses (including attorneys' fees) that it may incur in enforcing this provision.

b. Compliance. To the extent applicable to Company, it shall at all times comply with all statutory workers' compensation and employers' liability requirements covering its employees with respect to activities performed under this Agreement.

9. Export Control Laws.

a. This Agreement is made subject to the laws and regulations concerning the export and re-export of products, services or technical information that the U.S. government may impose from time to time, and to exceptions thereunder, such as those applying to Fundamental Research, pursuant to the ITAR (22 CFR 12.11) and the EAR (15 CFR 734.8) and that it is anticipated that no export controlled information or materials will be exchanged or generated in the course of this Agreement. If an export license is required, Company agrees to pay any fees or expenses incurred by Columbia or Company to obtain an export license. Company agrees that it will not disclose or re-export any Products to any countries for which the U.S. Government requires an export license, without any required license.

10. Breach and Cure.

a. Breach. In addition to applicable legal standards, Company will be deemed to be in material breach for: (i) failure to comply with governmental requests directed to Columbia or Company under Section 7b; (ii) failure to obtain and maintain insurance in the amount and of the type provided for in Section 9; and (iii) failure to comply with the Export Laws under Section 10.

b. Cure. Either party will have the right to cure its material breach. The cure shall be effected within a reasonable period of time but in no event later than thirty (30) days after notice of any breach given by the non-breaching party.

11. Term of Agreement.

a. Effective. This Agreement is effective as of the Effective Date and continues in effect until its expiration or termination under this Section 12.

b. Term. Unless terminated earlier under any provision of this Agreement, the term of this Agreement is twelve (12) months from the Effective Date.

c. Termination by Columbia. This Agreement may be terminated by Columbia: (i) upon written notice to Company for Company's material breach of the Agreement and Company's failure to cure such material breach under Section 11b; (ii) if Company becomes insolvent or is generally not paying its debts as such debts become due; and (iii) if Company ceases to conduct business as a going concern. Termination under this Section 12c will be effective upon the date of notice sent under Section 13.

d. Survival. 2d (Improvements), 4 (Confidentiality), 5 (Disclaimer), 6 (Use of Name), 7 (Compliance), 9 (Indemnification and Insurance), 10 (Export Control), 12d (Survival), 12e (Accrued Rights and Obligations), 13 (Notices), 15 (Waiver and Election of Remedies), 18 (Entire Agreement), 19 (Severability), and 21 (Governing Law) will survive any termination or expiration of this Agreement.

e. Accrued Rights and Obligations. Any termination of this Agreement will not adversely affect any rights or obligations that may have accrued to either party before the date of termination.

13. Notices. Any notice required or permitted to be given under this Agreement will be sufficient if in writing and will be considered given (a) when mailed by certified mail (return receipt requested), postage prepaid, or (b) on the date of actual delivery by hand or overnight delivery, with receipt acknowledged,

if to Columbia, to: Executive Director

Columbia Technology Ventures

Columbia University

80 Claremont Avenue, #4F, Mail Code 9606

New York, NY 10027-5712

copy to: General Counsel

Columbia University

412 Low Memorial Library

535 West 116^th Street, Mail Code 4308

New York, New York 10027

if to Company, to: [Address provided by Company in the course of accessing this license]

14. Assignment. This Agreement and all rights and obligations hereunder may not be assigned by either party without the written consent of the other party. Any attempt to assign without compliance with this provision will be void.

15. Waiver and Election of Remedies. The failure of any party to insist upon strict adherence to any term of this Agreement on any occasion will not be considered a waiver or deprive that party thereafter of the right to insist upon strict adherence to that term or any other term of this Agreement.

16. Binding on Successors. This Agreement will be binding upon and inure to the benefit of the parties and their respective successors and assigns to the extent assignment is permitted under this Agreement.

17. Independent Contractors. It is the express intention of the parties that the relationship between Columbia and Company will be that of independent contractors and will not be that of agents, partners, or joint venturers. Nothing in this Agreement is intended or will be construed to permit or authorize either party to incur, or represent that it has the power to incur, any obligation or liability on behalf of the other party.

18. Entire Agreement; Amendment. This Agreement, together with the Exhibits, sets forth the entire agreement between the parties concerning the subject matter hereof. This Agreement may be amended only by a written agreement duly executed by the parties.

19. Severability. If any provision of this Agreement is held by a court of competent jurisdiction to be unenforceable because it is invalid, illegal or unenforceable, the validity of the remaining provisions will not be affected, and the rights and obligations of the parties will be construed and enforced as if the Agreement did not contain the particular provisions held to be unenforceable, unless such construction would materially alter the meaning of this Agreement.

20. No Third-Party Beneficiaries. Except as expressly set forth herein, the parties hereto agree that there are no third-party beneficiaries of any kind to this Agreement.

21. Governing Law. This Agreement is governed by and construed under the internal substantive laws of the State of New York as is applicable to agreements made and wholly performed within the State of New York, and without reference to the conflict or choice of laws principles of any jurisdiction. The parties agree that any and all claims arising under this Agreement or relating thereto shall be heard and determined either in the United States District Court for the Southern District of New York or in the Courts of the State of New York located in the City and County of New York, and the parties agree to submit themselves to the personal jurisdiction of those Courts and to waive any objections as to the convenience of the forum.

22. Execution in Counterparts; Facsimile or Electronic Transmission. This Agreement may be executed in counterparts and by facsimile or electronic transmission. This Agreement is not binding on the parties until it has been signed below on behalf of each party.

IN WITNESS WHEREOF, Columbia and Company have caused this Agreement to be executed by their duly authorized representatives as of the day and year that is first written above.

Patents Exhibit A

US provisional Application No.: 62/993,638

Inventors: Keith Yeager and Robert Stark

Columbia IR# CU20296

US provisional Application No.: 63/000,403

Inventors: Keith Yeager and Robert Stark, Max B Summers

Columbia IR# CU20296

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