CNS/Neurology
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Neuroscience
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This technology is a tool to identify compounds that block the activity of TIA1, an RNA-binding protein that regulates stress granule formation and the generation of pathological forms of tau protein, and is implicated in a range of neurodegenerative diseases.
This technology is a group of lead compounds that effectively prevent TIA1 multimerization and subsequent aggregation of tau protein for treatment of neurodegenerative diseases.