Columbia Technology Ventures
Oncology
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Adolfo A. Ferrando M.D., Ph.D.
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This technology is a murine model of angioimmunoblastic T-cell lymphoma with Rhoa G17V expression, which recapitulates the features of human disease for further study and therapeutic development.
This technology is a mouse model expressing the human oncogene T cell leukemia homeobox protein-1 (TLX1), which mimics the genetic and molecular signatures of T cell acute lymphoblastic leukemia (T-ALL).
This technology describes the synthesis and characterization of small molecule NT5C2 inhibitors for the treatment of relapsed and chemotherapy-resistant acute lymphoblastic leukemia (ALL) and T-cell acute lymphoblastic leukemia (T-ALL).