This technology includes two chemical compounds that are phosphodiesterase type 5 (PDE5) inhibitors with a benzonaphthyridine derivative chemical scaffold that has not previously been used to ...
This technology is an engineered immunomodulatory biomaterial for controlled, localized release of IKKb Inhibitor VIII, synonymously, ACHP, a small molecule inhibitor targeting NF-kB-dependent ...
This technology is a small molecule protein therapeutic for systolic heart failure, which improves contractility without an unwanted rise in a patient’s heart rate.
This technology is a targeted anti-tumor agent designed to treat adenoid cystic carcinoma (ACC) by utilizing retinoid receptor modulation to promote cancer cell differentiation and selective cell ...
This technology identifies SSRI compounds as potential therapies for treating chronic obstructive pulmonary disease (COPD) via inhibition of cigarette smoke-induced proteolytic enzyme ...
This technology describes four chemical compounds that are capable of inhibiting the ID2/VHL interaction for downstream inhibition of tumor growth and angiogenesis.
This technology is a comprehensive compound design and preclinical testing platform that can be used to develop multifunctional drugs for Alzheimer’s disease, and has already led to the ...
This technology is a method of reprogramming cellular metabolism to treat neurodegenerative disorders by downregulating catabolism and upregulating anabolism in cells.
This technology is an immunosuppressant that suppresses T cell proliferation and can be used to treat organ transplant rejection, autoimmune or inflammatory conditions, and modulate the immune ...
