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Metabolic modulation of cells for neurodegenerative disorder treatment
CU17362

Functional or metabolic assay for disease cell lines.

11AssayAnabolismCatabolism
4Christine XuKaren Sophia ParkStephen H. Tsang M.D., Ph.D.
Kristin Neuman
Ophthalmology
College of Physicians and Surgeons (CUMCColumbia University Medical Center (CUMC)
2023-04-15
Fusion protein as target for brain cancer therapy
CU12240

Diagnostic assay for glioblastoma multiforme.

13AssayChemotherapyGlioblastoma
Anna LasorellaAntonio IavaroneRaul Rabadan
Kristin Neuman
Biomedical InformaticsNeurologyPediatrics
Columbia University Medical Center (CUMC)
2022-09-15
Endoplasmic reticulum stress relievers for increasing the production of insulin in beta cells
CU12150

Utilization in research studying ER stress as a recovery assay.

10AssayBeta cellCombination therapy
Dieter EgliLinshan ShangRudolph L. Leibel MD
Kristin Neuman
Pediatrics
Columbia University Medical Center (CUMC)
2018-08-16
Small molecule therapeutics to treat treatment-resistant ALL and T-ALL
CU19220

This technology describes the synthesis and characterization of small molecule NT5C2 inhibitors for the treatment of relapsed and chemotherapy-resistant acute lymphoblastic leukemia (ALL) and T-cell acute lymphoblastic leukemia (T-ALL).

10AssayAcute lymphoblastic leukemiaCancer cell
4Adolfo A. Ferrando M.D., Ph.D.Arie ZaskBrent Stockwell
Joan Martinez
Biological SciencesInstitute for Cancer GeneticsProgram in Cellular, Molecular, Structural and Genetic Studies
Columbia University Medical Center (CUMC)Faculty of the Arts & Sciences
2021-02-03