Divisions
Mailman School Of Public Health (MSPH)
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Virome-capture-sequencing (VirCapSeq) for viral infection diagnosis
CU18221
VirCapSeq-VERT: a high-throughput, cost-effective viral capture and sequencing platform enabling broad, sensitive vertebrate virus detection and discovery.
Tags
Chain reaction
DNA sequencing
Massive parallel sequencing
Inventors
Cheng Guo
Nischay Mishra
Orchid Allicock
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-09-04
Machine learning pipeline for neoantigen prioritization in personalized immunotherapies
CU25375
ImmuneMirror: integrative ML pipeline predicting immunogenic neoantigens by combining processing, transport, binding, and recognition factors.
Tags
Antigen
Biomarker
Cancer immunotherapy
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-07
Integrated AI platform for causal discovery and drug validation
CU25378
Cloud-based AI suite enabling causal discovery, multimodal data integration, and translational drug validation for personalized medicine.
Tags
Antigen
Artificial intelligence
Bias (statistics)
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-07
Penalized inverse-variance weighted estimator for robust Mendelian randomization
CU25374
Penalized IVW estimator improves Mendelian randomization robustness to weak instruments and pleiotropy, with fast, bias-reducing correction.
Tags
Biomarker
Biometrics
Causal inference
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-07
Diagnostic peptides for Lyme disease serodiagnosis
CU25107
Rapid, affordable Lyme diagnostic using two specific peptides; enables early, at-home, point-of-care serodiagnosis with higher accuracy.
Tags
Antibiotic
Antibody
Borrelia burgdorferi
Inventors
Rafal Tokarz
W. Ian Lipkin M.D.
Manager
Kristin Neuman
Departments
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-04-04
A peptide microarray for serodiagnosis of exposure to high-threat hemorrhagic fever viruses
CU23088
Peptide microarray identifies immunoreactive epitopes for high-specificity serodiagnosis of hemorrhagic fevers, distinguishing infection from vaccination.
Tags
Antibody
Blood plasma
Blood transfusion
Inventors
Lisa Hensley
Nischay Mishra
Sunil Kumar Dubey
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2024-01-10
Collections
Platform/Research Tool
CASE adherence index: A method for measuring adherence to antiretroviral therapy
CU24088
CASE Adherence Index: a 3-question, rapid ART adherence measure with strong virologic correlation for clinics and trials.
Tags
Adherence (medicine)
Antiviral drug
HIV
Inventors
Sharon Mannheimer M.D.
Manager
Jerry Kokoshka
Departments
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2023-11-30
Diagnosis of viral disease in tilapia populations
CU15044
Identifies TiLV-specific nucleic acid and protein markers for rapid, high-throughput tilapia viral diagnostics and monitoring.
Tags
DNA sequencing
Fish farming
High-throughput screening
Inventors
Nischay Mishra
Sandra Abel Nielsen
Thomas Briese
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2015-11-06
Genetic sequence database for identifying bacteria, pathogenicity, and antibiotic resistance
CU23199
Curated million-sequence database enabling rapid bacterial ID, virulence and antibiotic-resistance detection for diagnostics.
Tags
Antimicrobial resistance
Biological database
Drug development
Inventors
Amit Ranjan
Cheng Guo
Thomas Briese
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-29
Novel algorithms for population structure inference
CU25377
ERStruct: fast, AI-augmented population structure inference from whole-genome data; scalable, MATLAB/Python package for precise PCA components.
Tags
Algorithm
Allele frequency
Artificial intelligence
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-07
One step assay for rapid and selective diagnosis of arboviruses
CU16221
Multiplex one-step qPCR quickly differentiates Zika, Dengue, Chikungunya, and West Nile from serum or urine samples.
Tags
Arbovirus
Assay
Chikungunya
Inventors
Nischay Mishra
Rafal Tokarz
W. Ian Lipkin M.D.
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2017-08-18
Multi-knockoff filter for high-dimensional survival -omics with controlled false discovery rate
CU25376
CoxMKF: a multi-knockoff survival mediation method that guarantees finite-sample FDR control with stable, data-driven thresholds.
Tags
Assay
Bioinformatics
Biomarker
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-07
Deep learning framework for semiparametric causal mediation analysis
CU25372
DeepMed enables bias-reduced causal mediation with non-sparse deep nets, offering semiparametric guarantees and an open-source R package.
Tags
Artificial neural network
B testing
Big data
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-08-07
Platform to identify causal proteins in Alzheimer's for drug discovery
CU25371
Integrated Mendelian-randomization and AlphaFold3 pipeline identifies causal Alzheimer's proteins to guide drug targets and diagnostics.
Tags
Assay
Causality
Drug development
Inventors
Zhonghua Liu
Manager
Joan Martinez
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-07-31
NeuroScore AI: an automated program for Alzheimer’s Disease risk scoring
CU24217
NeuroScore AI automates transcription and scoring of cognitive test audio to quantify Alzheimer's risk, speeding, unbiased.
Tags
Cognition
Inventors
Allison Aiello
Manager
Joan Martinez
Departments
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2024-04-01
Collections
CNS/Neurology
Medical Device
Digital Health (Software, AI, bioinformatics, etc)
Non-invasive method for detection of cancer methylomes
CU21185
Non-invasive methylation profiling of tumor cfDNA enables early cancer detection, tumor origin, and targeted treatment insights.
Tags
5-Methylcytosine
Antibody
Assay
Inventors
Hui Zhou
Regina Santella Ph.D.
Zhiguo Zhang
Manager
Joan Martinez
Departments
Environmental Health Science
Genetics & Development
Institute for Cancer Genetics
Divisions
Mailman School Of Public Health (MSPH)
Columbia University Medical Center (CUMC)
Release Date
2023-08-04
Collections
Oncology
Assay for neurotransmitter leakage detection using fluorescent analogues
CU22294
Real-time, non-radioactive fluorescent assay tracks vesicular neurotransmitter leakage in cells for high-throughput neurological research.
Tags
Assay
High-throughput screening
Isotopic labeling
Inventors
Gary Miller
Meghan L. Bucher
Manager
Joan Martinez
Departments
Environmental Health Science
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2023-09-08
Collections
CNS/Neurology
Platform/Research Tool
Method for identifying vertebrate viruses using multiplexed, high-throughput genome sequencing
CU16058
Virome-Capture-Sequencing (VirCapSeq-VERT) enables high-throughput, cost-effective vertebrate virus detection and discovery.
Tags
Chemical library
Global health
Ulcerative colitis
Inventors
Amit Kapoor
Omar Jabado
Thomas Briese
Manager
Kristin Neuman
Departments
Biological Sciences
Epidemiology
Mailman School Of Public Health (MSPH)
Divisions
Mailman School Of Public Health (MSPH)
Faculty of the Arts & Sciences
Release Date
2025-09-04
Tagmentation-based method to improve global DNA methylation assays
CU23112
A tagmentation-based, antibody-free MeDIP-seq method streamlines DNA methylation analysis with less input DNA and faster library prep.
Tags
Antibody
Blood plasma
Chemical library
Inventors
Hui Zhou
Hui-Chen Wu
Regina Santella Ph.D.
Manager
Joan Martinez
Departments
Environmental Health Science
Genetics & Development
Institute for Cancer Genetics
Divisions
Mailman School Of Public Health (MSPH)
Columbia University Medical Center (CUMC)
Release Date
2023-08-15
Collections
Oncology
Optimizing multiplex decisions using machine learning for cancer screening
CU23231
Bayesian optimization reduces calculations for multiplex cancer screening without assumptions, updating predictions with real-world data.
Tags
Algorithm
Bayesian inference
Biomarker
Inventors
Ying Kuen (Ken) Cheung
Manager
Sara Gusik
Departments
Biostatistics
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2023-07-14
Collections
Oncology
Medical Device
Digital Health (Software, AI, bioinformatics, etc)
High-throughput assay for detection of Zika exposure
CU17122
High-throughput Zika serology using epitope signatures enables rapid, differential exposure detection, distinguishing past from acute infections.
Tags
Assay
Chikungunya
Differential diagnosis
Inventors
Adrian Caciula
Nischay Mishra
Thomas Briese
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2018-02-15
Method of biomarker testing for autism spectrum disorder for early intervention
CU23349
Biomarker-based newborn metabolomic profiling enables early ASD risk identification and intervention, enhancing timely, personalized treatment.
Tags
Applied behavior analysis
Autism spectrum
Blood plasma
Inventors
Camilla Stoltenberg
Oliver Fiehn
W. Ian Lipkin M.D.
Manager
Kristin Neuman
Departments
Biostatistics
Epidemiology
Molecular and Cellular Biology
Divisions
Mailman School Of Public Health (MSPH)
Technology Transfer Services
Release Date
2024-02-15
Collections
CNS/Neurology
Medical Device
Rapid Molecular Differential Detection of SARS-CoV-2
CU20260
Rapid, multi-virus PCR assay enables differential, rapid detection of SARS-CoV-2, influenza A/B, improving diagnostic accuracy.
Tags
Assay
Blood plasma
Epidemiology
Inventors
Nischay Mishra
Simon H. Williams
Thomas Briese
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2022-08-20
Immunohistochemical test for determining the role of Aflatoxin B1 in liver cancer
957
Immunohistochemical AFB1-DNA adduct antibody links aflatoxin exposure to human liver cancer risk and research tools.
Tags
Antibody
Antigen
Carcinogen
Inventors
I. Bernard Weinstein M.D.
Ling Ling Hsieh
Regina Santella
Manager
Sara Gusik
Departments
Anesthesiology
Mailman School Of Public Health (MSPH)
Medicine
Divisions
Mailman School Of Public Health (MSPH)
Columbia University Medical Center (CUMC)
Release Date
2016-04-07
Serochip for the diagnosis of tick-borne diseases
CU19325
A programmable peptide microarray enables rapid, high-throughput, single-step serologic diagnosis of multiple tick-borne diseases.
Tags
Antibody
Assay
Epidemiology
Inventors
Adrian Caciula
Nischay Mishra
Rafal Tokarz
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-09-04
Multiplexed serological platform for detection of SARS-CoV-2 exposure
CU20309
High-throughput microarray identifies SARS-CoV-2–specific epitopes, distinguishing them from other coronaviruses for precise serodiagnosis.
Tags
Antibody
Coronavirus
Epitope
Inventors
Cheng Guo
Jiahai Lu
Nischay Mishra
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2020-04-02
Collections
Platform/Research Tool
Nanobodies for diagnosis, treatment and prevention of infection and disease caused by SARS-CoV-2 and variants
CU21304
Broad-spectrum SARS-CoV-2 nanobodies enable diagnosis, treatment, and prevention across variants with easier delivery and stability.
Tags
Angiotensin
Assay
Enzyme
Inventors
Thomas Briese
W. Ian Lipkin M.D.
Manager
Kristin Neuman
Departments
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2023-02-17
Collections
Platform/Research Tool
Non-invasive quantification of nuclear brain images
CU14274
Non-invasive estimation of arterial input function using PET data and EHRs to quantify brain imaging without blood sampling.
Tags
Brain
CT scan
Catheter
Inventors
Andrew F. Laine
Arthur Mikhno
Francesca Zanderigo
Manager
Jerry Kokoshka
Departments
Biomedical Engineering
Biostatistics
Psychiatry
Divisions
Mailman School Of Public Health (MSPH)
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2018-08-01
