Applications:
Gene expression modulator. This technology is a nucleic acid-based polymer system that can be engineered to target the expression of specific cancer-associated genes for therapeutic benefit. This technology is a peptide nucleic acid (PNA)-based platform that can specifically alter the expression of target genes in cancer cells.
Finally, off-target gene expression is a common and dangerous problem for existing gene therapy agents. Applications:
AAV deliverable gene therapy. Capable of inducing gene overexpression or knock down.
This novel software elucidates the functional connectivity between signaling networks and transcriptional networks, providing new insights into gene regulatory pathways and the mechanisms that control gene expression. Variation in the expression of genes can be traced back to alterations in transcription factor activity, which results from mRNA expression levels. Variation in the expression of genes can be traced back to alterations in transcription factor activity, which results from mRNA expression levels.