Columbia Technology Ventures

A broad-spectrum antimicrobial disinfectant

This technology is a disinfectant composed of a combination of naturally antimicrobial botanical blends and popular synthetic antimicrobials like para-chloro-meta-xylenol (PCMX).

Unmet Need: Broad-spectrum antimicrobial for infection prevention

Current disinfectants are only somewhat effective in preventing infection, with 5% of hospital patients ending up with healthcare-associated infections. While Dettol, a disinfectant composed of PCMX, pine oil and castor oil, is rigorously implemented, these infection statistics imply that there is much room for improvement. Improvements in scope of antimicrobial activity, whether it is applicable to a broader range of microbes or has more lasting antimicrobial effects, have positive implications for both general public health and the healthcare system.

The Technology: Improved disinfectant combining botanical and synthetic antimicrobials for broad-spectrum disinfection

This disinfectant combines the natural antibacterial and antifungal activities of essential oils and botanicals with a powerful chemical disinfectant such as para-chloro-meta-xylenol (PCMX). This technology leverages the observation that many botanical components have inherent antimicrobial and antifungal capabilities but are less harsh then chemical agents. As such, they often exhibit reduced risk of skin irritation compared with synthetic disinfectants. This technology combines the natural disinfectant properties of essential oils and botanicals with the lasting protection of synthetic disinfectants such as PCMX, chlorhexidine, and quaternary ammonium salts to generate a broad-spectrum disinfectant formulation for superior protection against infection in high-risk environments such as hospitals.

Applications:

  • Antimicrobial personal healthcare products
  • Disinfectant for agricultural and animal husbandry products
  • Disinfectants for childcare
  • Disinfectants for burn or open wounds
  • Surface disinfectants for clinical and household uses
  • Laboratory disinfectant
  • Laundry detergent additive
  • Anti-acne products

Advantages:

  • Combines of a wide variety of natural antimicrobial and antifungal botanicals for reduced harshness upon topical administration
  • Combination of different synthetic compounds allows for disinfection against both gram-positive and gram negative bacteria as well as fungi and viruses
  • Broad effectiveness allows for use in clinical and household applications

Lead Inventor:

Shanta M. Modak, Ph.D.

Patent Information:

Patent Pending (US 20150374352)

Related Publications:

Tech Ventures Reference: