A deep learning substitute for Gadolinium contrast detects focused ultrasound-induced blood-brain barrier (BBB) opening

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This technology is a computational algorithm that can minimize the dose of gadolinium-based contrast agents used in magnetic resonance imaging (MRI) without compromising imaging quality.
Unmet Need: Reduction of contrast agent use in MRI.
Furthermore, the cost of Gd agents is a large contributor to the high cost of MRI.
This technology is a deep learning algorithm that uses ultrasound imaging data to extract cervix geometry and predict preterm birth (PTB) risk.
The Technology: Deep-learning algorithm to accurately predict preterm birth from transvaginal ultrasound images.
This technology uses machine learning to automatically detect and label cervical physiological features from TVUS images of patients in the 2nd and 3rd trimesters of pregnancy, records PTB markers and other important cervical and lower uterine features, combines additional patient data from electronic medical records with TVUS sonograms, and applies deep learning models to predict PTB risk.
This technology is an algorithm that utilizes deep learning tools to identify and diagnose diseases from MRI scans.
Diagnostic modalities are limited and underdeveloped since MRI scans require visual inspection by trained medical professionals.
Automated deep learning-based algorithms show great promise in their application to neuroimaging diagnostics, yet current deep learning MRI technologies are inaccurate in their ability to classify diseases.
    • Tags
      • 14
        Blood–brain barrier
      • 9
        Drug delivery
      • 8
        Brain
      • 6
        Cavitation
      • 6
        Magnetic resonance imaging
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    • Categories
      • 24
        Biology
      • 24
        Branches of biology
      • 18
        Neuroscience
      • 6
        Computational neuroscience
      • 17
        Anatomy
      • Add ...
    • Inventors
      • 10
        Elisa Konofagou
      • 3
        James Junesik J. Choi
      • 2
        Andrew F. Laine
      • 2
        Arthur Mikhno
      • 2
        Chen Chen
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    • Manager
      • 12
        Dovina Qu
      • 7
        Jerry Kokoshka
      • 2
        Kristin Neuman
      • 2
        Sara Gusik
      • 1
        Greg Maskel
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    • Departments
      • 15
        Biomedical Engineering
      • 5
        Psychiatry
      • 5
        Radiology
      • 3
        Neurology
      • 2
        Biomedical Informatics
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    • Divisions
      • 17
        Fu Foundation School of Engineering and Applied Science (SEAS)
      • 15
        Columbia University Medical Center (CUMC)
      • 1
        College of Physicians and Surgeons (CUMC)
      • 1
        Faculty of the Arts & Sciences
      • 1
        Intermountain Medical Group
      • Add ...
    • Reference Number
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    • Release Date
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