A non-irritating, effective botanical antimicrobial formulation for combating pathogens

Unmet Need: Irritant-free agent for combating a broad spectrum of microbes

Current antimicrobial formulations commonly used in hospital health care and personal care contain harsh chemicals that are potentially toxic cannot be used for oral care. The increasing prevalence of microbes that are resistant to multiple drugs highlights the need for more effective compounds to broadly fight pathogenic organisms. Although alcohol-based products such as hand sanitizers are a possible solution to resistant organisms, their topical use disrupts skin’s moisture and pH balance, leading to skin irritation that is susceptible to microbial infection. Currently, there are limited available antimicrobial compositions that are non-irritating, safe, and effective for repeated use.

The Technology: Alcohol-free botanical antimicrobial composition for oral care

This technology is an alcohol-free antimicrobial composition that contains botanicals, synthetic antimicrobial agents, and essential oils that effective against a broad spectrum of pathogens. It can be supplemented with solvents, stabilizers, anti-irritants, organic acids, and surfactants to enhance the formulation and reduce irritation. Flavoring agents for use in an oral care product such as toothpaste, an oral rinse, oral care wipe, or oral care gel can also be added. As a result, this technology provides an improved and effective antimicrobial that is safe enough for repeated oral use.

This technology has been validated to be effective against Methicillin-resistant Staphylococcus aureus (MRSA), Candida albicans, and Streptococcus mutans.

Applications:

Personal care products such as hand soap, body creams, shower gel, etc.
Oral care products such as toothpaste, oral rinse, oral care wipe, oral care gel
Routine oral care for infection prevention
Treatment for oral infection
Topical antimicrobial cream or products for veterinary use
Topical antifungal cream for Athlete’s foot
Diaper rash cream
Medical care products such as disinfectants, wound dressings, and topical cream
Household care products such as wipes and cleaners for surface disinfecting
Healthcare products such as surface and hand sanitizers/soaps for hospitals and wound treatment
Veterinary products
Industrial cleaners and disinfectants
Natural preservatives for food, beverage, and cosmetics
Baby care products
Geriatric care products

Advantages:

Increased antimicrobial activity compared to individual components and leading brand name products
Multiple active ingredients decrease the possibility of organisms developing resistance
Non-irritating
Multiple formulations including flavors for oral products to increase utility
Effective against a broad spectrum of yeast and bacteria
Safe to use on a variety of surfaces

Lead Inventor:

Shanta M. Modak, Ph.D.

Patent Information:

Patent Status

Tech Ventures Reference:

IR CU14244, CU14359, CU15074
Licensing Contact: Sara Gusik