This technology is an integrated microwell-based multi-tissue culture system that contains standardized systems allowing for automated maintenance of cultures over time.
Cellular culture practices are widely used in research in development to better understand cells in their natural environment and their response to genetic and pharmaceutical perturbations. However, standard tissue culture setups do not reflect the true biology of their native organ of origin which may confound results. Moreover, the establishment and maintenance of cell cultures can be expensive and incredibly labor-intensive, requiring constant attention by researchers to ensure viability. There is a need for user-friendly or automated cell culture systems that more accurately model cell and tissue environments.
This technology is a user-friendly, microwell-based multi-tissue culture system. The system utilizes standardized sizing and components, enabling compatibility with existing analytical and robotic equipment. Smart features such as integration of onboard pumping, electrical stimulation, sensing, and remote communication enable automated culture maintenance. The ability to simultaneously culture multiple tissues enables improved modeling of native tissue environments and systemic responses to genetic or therapeutic perturbations.
Patent Pending (WO/2023/192899)
IR CU22271
Licensing Contact: Beth Kauderer
