Columbia Technology Ventures

Biofilm-resistance through durable polymeric coating

This technology is a durable, film-forming polymeric coating that prevents biofilm formation by combining hydrophilic and hydrophobic polymers with botanicals, essential oils, organic acids, and silver salts.

Unmet Need: Durable, sustainable, and effective biofilm prevention

Biofilms are ubiquitous in nature and can be a main contributor to human disease. Current methods to prevent biofilm formation rely on antimicrobial agents, physical removal, and nanoparticle-based treatments. However, these approaches are short-lived, unsustainable, and risk antimicrobial resistance. Additionally, they often fail to prevent microbial colonization across diverse surfaces and environments. There is a critical need for a durable, versatile, sustainable, and cost-effective solution that inhibits biofilm formation while minimizing the associated risks, thereby improving outcomes in wound care, water filtration, and medical device maintenance.

The Technology: Botanical, film-forming coating for durable and sustainable biofilm resistance

This technology is a surface coating that prevents biofilm formation by combining hydrophilic and hydrophobic polymers to form a smooth, long-lasting film. Essential oils and organic acids are incorporated to inhibit microbial colonization and biofilm development, while optional silver salts can enhance antimicrobial activity. The coating adheres to various surfaces including polyvinyl chloride, polyurethane, silicone latex, cellulose, and skin. It offers robust protection against biofilm formation, resists wash-off, and is well-suited for use in challenging applications.

Applications:

  • Surface coatings for medical devices
  • Antibacterial wipes for sanitization
  • Wound dressings
  • Facial masks and wipes for acne treatment
  • Membranes for water filtration systems

Advantages:

  • Prevents microbial colonization and biofilm formation
  • Durable and resistant to wash-off
  • Eco-friendly and sustainable
  • Cost-effective
  • Reduces risk of antimicrobial resistance
  • Compatible with a wide range of substrates

Lead Inventor:

Shanta Modak, Ph.D.

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