Columbia Technology Ventures

Biofuel and specialty chemical production from waste by-products using genetically-engineered bacteria

This technology is a genetically modified sulfur oxidizing and iron-reducing bacterial strain that can produce biofuels and specialty chemicals from waste by-products.

Unmet Need: Method for managing waste while producing biofuels and chemicals

Natural gas, a finite resource, must be replaced with a sustainable fuel source for generations to come. Additionally, industrial waste streams associated with natural gas fields accumulate large amounts of sulfur as a by-product, which is currently managed by fiscally and energy expensive chemical means. Genetically modified organisms that can produce biofuels and other valuable chemical products are a promising alternative due to their potential to utilize waste streams of industrial processes as a feed source for producing both biofuels and specialty chemicals. However, no organism to date has been identified for converting industrial-scale quantities of sulfur-based waste into biofuels or chemicals.

The Technology: Sulfur-oxidizing and iron-reducing bacteria for production of biofuels from waste

This method for producing biofuels employs genetically modified sulfur-oxidizing and iron-reducing bacterial (SOIRB) strains to populate two bioreactors. The bacteria in the first bioreactor produce isobutanol and an iron source for the second bioreactor, which in turn produces additional isobutanol and feedstock back to the first. Unlike existing methods for bio-processing sulfur-containing waste streams, these organisms grow in conditions that minimize potential contamination and do not require an expensive electron source. In this manner, the technology aims to close the fuel carbon cycle and reduce the extraction of raw hydrocarbons.

Applications:

  • Production of biofuels
  • Treatment of sulfur-containing industrial waste streams
  • Conversion of industrial waste streams to useful biofuels and specialty chemicals
  • “Off-grid” production of biofuels and chemicals in combination with a solar photovoltaic electricity source
  • Sulfur removal from fossil fuels

Advantages:

  • Ability to treat and convert waste streams into useful chemicals and fuels
  • Carbon neutral production of fuel
  • Reduced electrical power requirement
  • Reduced waste feedstock costs
  • Cost-effective biofuel and chemical production process
  • Modular platform for specialty chemical production

Lead Inventor:

Scott A. Banta, Ph.D.

Patent Information:

Patent Status

Related Publications:

*Inaba Y, Kernan T, West AC, Banta S. “Dispersion of sulfur creates a valuable new growth medium formulation that enables earlier sulfur oxidation in relation to iron oxidation in Acidithiobacillus ferrooxidans cultures” Biotech Bioeng. 2021 Jun 04; 118(8): 3225-3238.

Tech Ventures Reference:

  • IR CU12175, CU16018, CU14270

  • Licensing Contact: Dovina Qu