This technology is a method of bolstering immune defenses in intestinal tissue for the prevention and treatment of graft-versus-host disease, which is often caused by allogeneic hematopoietic stem cell transplantation. Prevention and treatment of GVHD following HPSC transplantation. Allogeneic hematopoietic stem cell (HPSC) transplantation, a common therapy for various genetic diseases and cancers, often results in potentially fatal complications, such as graft-versus-host disease (GVHD).
Treatment to reduce and/or prevent organtransplantrejection or complications of transplant. This approach can be used to treat, reduce, or prevent transplantrejection, autoimmune diseases, and graft-versus-host disease by promoting systemic immune tolerance or immunosuppression. This approach can be used to treat, reduce, or prevent transplant rejection, autoimmune diseases, and graft-versus-host disease by promoting systemic immunetolerance or immunosuppression.
Preventative medicine for multiple organ failure. Direct prevention and treatment of shock-induced multiple organ failure. This technology is a pharmacological intervention targeting localized inflammatory responses in trauma and hemorrhagic shock to prevent multiple organ failure.