Cell therapy methods for improved transplant acceptance

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This technology is a method of bolstering immune defenses in intestinal tissue for the prevention and treatment of graft-versus-host disease, which is often caused by allogeneic hematopoietic stem cell transplantation.
Prevention and treatment of GVHD following HPSC transplantation.
Allogeneic hematopoietic stem cell (HPSC) transplantation, a common therapy for various genetic diseases and cancers, often results in potentially fatal complications, such as graft-versus-host disease (GVHD).
Treatment to reduce and/or prevent organ transplant rejection or complications of transplant.
This approach can be used to treat, reduce, or prevent transplant rejection, autoimmune diseases, and graft-versus-host disease by promoting systemic immune tolerance or immunosuppression.
This approach can be used to treat, reduce, or prevent transplant rejection, autoimmune diseases, and graft-versus-host disease by promoting systemic immune tolerance or immunosuppression.
Preventative medicine for multiple organ failure.
Direct prevention and treatment of shock-induced multiple organ failure.
This technology is a pharmacological intervention targeting localized inflammatory responses in trauma and hemorrhagic shock to prevent multiple organ failure.
    • Tags
      • 16
        T cell
      • 12
        Immunotherapy
      • 10
        Neoplasm
      • 8
        Cytotoxic T cell
      • 7
        Transplant rejection
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    • Categories
      • 24
        Biology
      • 24
        Branches of biology
      • 19
        Anatomy
      • 22
        Biological systems
      • 22
        Organ systems
      • Add ...
    • Inventors
      • 3
        Hong Jiang
      • 3
        John Loike
      • 3
        Leonard Chess MD
      • 3
        Raphael Clynes MD, PhD
      • 3
        Sadna Budhu
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    • Manager
      • 6
        Jerry Kokoshka
      • 6
        Joan Martinez
      • 6
        Sara Gusik
      • 2
        Cynthia Lang
      • 2
        Dovina Qu
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    • Departments
      • 16
        Medicine
      • 4
        Biomedical Engineering
      • 4
        Biomedical Informatics
      • 3
        Physiology
      • 3
        Physiology and Cellular Biophysics
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    • Divisions
      • 21
        Columbia University Medical Center (CUMC)
      • 4
        Fu Foundation School of Engineering and Applied Science (SEAS)
      • 1
        Catalan Institution for Research and Advanced Studies (ICREA)
      • 1
        College of Physicians and Surgeons (CUMC)
      • 1
        Hematology
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    • Reference Number
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    • Release Date
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