This technology is a MEMS DSC device that utilizes thermally isolated microchambers for biochemical thermodynamic investigations.
Conventional DSC instruments are large, cumbersome, and require substantial sample consumption, hindering their potential widespread application. Miniaturized DSC devices have been developed. However, current MEMS DSC devices are limited by sensor sensitivity, complex calibration procedures, and auxiliary equipment requirements.
This technology is a disposable MEMS DSC device that utilizes inexpensively fabricated microfluidic structures on a commercially available Kapton polyimide film for thermodynamic characterization of biomolecules. The microfluidic structures in the device contain calorimetric channels for thermal isolation and a highly sensitive antimony-bismuth (Sb-Bi) thermopile. In addition, the device contains a layer of resistive microheaters and temperature sensors that are precisely aligned to calorimetric channels to produce accurate and convenient on-chip device calibration.
IR CU13359, CU15102
Licensing Contact: Dovina Qu