This technology is an ultrasound cardiac imaging technique that accurately generates 3D electromechanical activation maps of a beating heart for the diagnosis and treatment of cardiac arrhythmias
Diagnosis and treatment of cardiac arrhythmias require accurate characterization of irregularities in electromechanical activation. 3D imaging of electrical activity within the myocardium enables physicians to locate and monitor the pathological regions that may be targeted pharmacologically or by cardiac ablation. Current approaches for spatially resolving arrhythmias involve catheter probing of the endocardial wall, a procedure that is invasive, time-consuming, and limited by the accessibility of the lesion.
This non-invasive imaging method takes a series of ultrasound images of multiple areas within a heart chamber that are used to generate an anatomically accurate 3D electrical activity map of a beating heart. Electromechanical activation times are interpolated from each point within the image that are then put into a matrix that can be exported and analyzed in any third-party 3D-rendering software. This powerful imaging technique may be used for the diagnosis and monitoring of cardiac arrhythmias as well as disorders such as Wolff-Parkinson-White syndrome or pre-ventricular contraction. Furthermore, this platform may be used to inform cardiac ablation targeting strategies and treatment plans.
This technology has been validated in canine models of arrhythmic pathologies.
IR CU17221
Licensing Contact: Ron Katz
