Columbia Technology Ventures

Microdevice for small-scale calorimetric measurement

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“A MEMS differential scanning calorimeter for thermodynamic characterization of biomolecules” Micro Electro Mechanical Systems Conference.

“Demonstration of MEMS-based differential scanning calorimetry for determining thermodynamic properties of biomolecules” Sensors and Actuators B: Chemical.

The Technology: Cost-effective MEMS DSC device to examine biomolecular thermodynamics.

The Technology: Microfluidic device for enhancing temporal accuracy of time-resolved cryo-EM.

This technology is a microfluidic device that enables a reaction sample to flow in a co-flowing concentric buffer, resulting in a narrow distribution of reaction times for time-resolved cryo-electron microscopy (TR cryo-EM).

This technology has been validated with calculations and simulations, and the device is currently being 3D printed for testing.

This technology is an iMEMS device that enables targeted drug delivery.

This technology is an implantable microelectromechanical systems (iMEMS) device that may be remotely activated for targeted drug delivery in vivo.

As such, there is a need for a biocompatible implantable device that is easily manipulated by external signals for regulated drug delivery.