Microneedle-endoscope for drugging and sampling of inner ear
This technology is a microneedle-endoscope capable of perforating the round window membrane of the inner ear, allowing for drug delivery and sampling of inner ear fluids for therapeutics and diagnostics.
Unmet Need: Methods for drugging and/or sampling of the inner ear
Current methods to sample and/or deliver drugs to the inner ear are largely restricted by their invasiveness and potential long-term complications such as trauma and hearing loss. The round window membrane is a major physical barrier to the inner ear that requires careful consideration to maintain its integrity and prevent long-term damage. Furthermore, methods that allow for both sampling and drug delivery are lacking.
The Technology: Microneedle-Endoscope allows for drug delivery and sampling of inner ear
This device is fitted with a microneedle head and leverages endoscopic, camera-guided precision to carefully perforate the round window membrane of the inner ear. Capable of both drug delivery and fluid sampling, this technology safety traverses a major physical barrier to the inner ear without disrupting its structural integrity and mitigating potential long-term concerns such as hearing loss.
Applications:
- Diagnostic tool for sampling of the inner ear
- Drug delivery device for accessing the inner ear
- Clinical tool for perforating the round window membrane
Advantages:
- Safely navigates the round window membrane without undermining its integrity
- Allows for high precision with camera guidance
- Can both deliver therapeutics and sample inner ear fluid for diagnostic purposes
- Minimally invasive
Lead Inventors:
Patent Information:
Patent Pending(PCT/US2023/061545)
Related Publications:
Tech Ventures Reference:
IR CU21365, CU22203, CU22311, CU23068
Licensing Contact: Sara Gusik