Columbia Technology Ventures

Monoclonal Antibody Enhancing T Cell Reactivity in AIDS Treatments

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Adjuvant therapy
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Unmet Need: Method for modulating immune response with ligands for natural killer T cells.
A great diversity of lipids and glycolipids have been shown to bind to the various isoforms of CD1 and activate natural killer T cells.
This technology describes a series of novel compounds that have been identified to act as ligands for natural killer T cells and modulate the immune response of these cells.