Columbia Technology Ventures

MRI dual-head phased array with local shimming

This technology is a dual-head MRI system equipped with local shimming capabilities for simultaneous functional imaging of two adjacent subjects, facilitating the study of interpersonal interactions and social connections.

Unmet Need: Enhanced dyadic functional MRI with unobstructed interaction

Current functional MRI (fMRI) focuses on individual subjects, limiting the exploration of dynamic brain activities during real-life social interactions. Existing methodologies fall short in capturing the complex neural interplay associated with direct, simultaneous interpersonal connections. This remains crucial for advancing our understanding of social cognition and disorders. This gap hinders the development of more effective interventions and treatments for social disorders, as it overlooks the nuanced brain responses that emerge only within the context of direct human interaction. Addressing this limitation is vital for the progression of cognitive neuroscience and the development of therapeutic strategies for social behavioral disorders.

The Technology: Dual-head MRI with optimized local shimming

This technology is a dual-head phased array MRI system, designed with local shimming capabilities that maintain a clear line of sight between two subjects. By reducing the number of loop elements in the head/neck array configuration and finely adjusting the DC current distribution across the array, this system achieves optimal local shimming. This approach, supported by a blend of novel hardware and software solutions, ensures high-quality imaging for each subject within the dual-head setup without compromising the ability for visual interaction. This strategic design not only addresses the technical challenges of simultaneous imaging but also enhances the practical utility for studies requiring interpersonal engagement.

Applications:

  • Research tool for cognitive neuroscience studies on social interaction
  • Research tool for understanding brain activity in social disorders
  • Diagnostic aid for disorders like anxiety, depression, and autism
  • Educational tool for demonstrating live brain activity during social interaction

Advantages:

  • Allows for simultaneous fMRI of two subjects with optimized interaction
  • Reduces signal interference and improves image resolution with local shimming
  • Shortens image acquisition time and enhances efficiency
  • Facilitates studying the neural basis of social connections

Lead Inventor:

Ray Lee, Ph.D.

Tech Ventures Reference: