This technology is a wearable brain imaging device with extremely high spatiotemporal resolution that can distinguish individual neuronal activation events.
Functional brain mapping is an important contributor to neuroscience and an important step in neurosurgery to prevent excision of functional brain regions, which vary on an individual basis. Conventional methods of functional brain mapping, which seek to correlate neural activity to functional output from the subject, currently lack the spatiotemporal resolution required to identify neural events at the single cell level.
This noninvasive imaging device distinguishes individual action potentials from millions of neurons across large areas of the brain. The technology, called Time-of-Flight enhanced Functional Diffuse Optical Tomography (ToFF-DOT), relies on the integration of multiple highly advanced components into a printed, wearable, telemetry-capable imaging device. The technology implements molecular sensors of the chemical environment to report on cellular activity, such as blood oxygenation, calcium balance, and voltage-dependent activation. As such, this technology offers an unprecedented level of spatiotemporal resolution at the single cell level that may greatly advance brain imaging for neuroscience research.
IR CU19286
Licensing Contact: Greg Maskel