This technology is a tunable optoelectronic platform that can be used to generate high-resolution, three-dimensional images of cellular networks.
Current optoelectronic devices can detect, emit, and interface with light for a variety of applications including fiber optic communication systems and digital cameras. Although single optical fibers have been developed to image tissue structures, these approaches lack the spatial resolution to selectively image and activate individual neurons. Additionally, many optogenetic approaches are incompatible with certain biological applications due to the large footprint of traditional circuitry.
This technology is an optoelectronic system that consolidates photonic arrays with integrated circuitry to enable small-form microscopy. The technology guides fabrication techniques to yield a substrate-based interposer with embedded functional photonics. A silicon nitride optical array with tunable inference patterns further allows the user to produce a wide range of controllable optical outputs.
This technology has been validated with ChR2 mice models.
Patent Pending (US 20190391415)
Patent Pending (WO/2018/098146)
Patent Issued(US 11,662,643)
IR CU17223, CU18032, CU19330
Licensing Contact: Greg Maskell