This technology is a platform to organize nanoscale objects into a 3D array using DNA programmable interactions, that can be used to generate 3D hierarchically ordered materials for optical and energy applications.

Unmet Need: Self-assembly of designed 3D nanoarchitecture

Advancements in lithographic and additive manufacture methods have supported tremendous progress in the field of small-scale manufacturing over the past few decades. However, current methods to generate specifically designed 3D nanomaterials on demand, with prescribed diverse structures and composition, are limited by a reliance on the composition and interaction of particles within these architectures and with the underlying organization.

The Technology: Platform for organized self-assembly of nanoparticles to form 3D nanomaterials

This technology describes a technique for organizing nanoscale objects into a 3D array using repeating mesoscale motifs and their elemental blocks—nanoscale voxels (defined units of 3D space that can be empty or occupied) with DNA-encoded directional bonds that can carry encoded nano-cargo, to target specific molecules to use during self-assembly. The technology permits the production of complex, hierarchical, and diverse 3D architectures while reducing the amount of information required to encode such complex structures. This technology provides a bottom-up method for fabricating 3D architectures from a variety of nanocomponents by design, for use in a variety of nanomaterial applications. This technology has been validated with x-ray scattering and electron microscopy approaches.

Applications:

Platform for assembly and organization of 3D nanomaterials
Production of optical and energy materials
Production of information processing nanomaterials
DNA self-assembly for material physics, medicine, and biogenetics
Research tool for studying properties of 3D nanomaterials

Advantages:

Platform for production of self-assembling 3D lattices
Production of nanoscale objects using diverse types of nanocomponents
Ability to customize properties of 3D nanomaterials via bottom-up approach

Lead Inventor:

Oleg Gang, Ph.D.

Patent Information:

Patent Pending

Related Publications:

Kahn JS, Minevich B, Michelson A, Emamy H, Kisslinger K, Xiang S, Kumar SK, Gang O. "Encoding hierarchical 3D architecture through inverse design of programmable bonds" ChemRxiv, 2022 Sept 28

Tech Ventures Reference:

IR CU22393
Licensing Contact: Greg Maskel

Platform for the assembly of 3D hierarchically-organized nanomaterials