This technology is a non-device transcatheter repair strategy for closure of Patent Foramen Ovale (PFO) membranes using bipolar radiofrequency signals to limit embolic complications.
Current treatments for Patent Foramen Ovale (PFO) use implantable devices to seal the cardiac defect between the right and left atria. Implantable devices remain permanently encapsulated by atrial endothelial tissue, preventing left atrial access, which may be required for future interventional procedures. Device-based solutions are intrinsically associated with procedural-based complications such as thrombosis, infection, device failure, and embolization. There are currently no treatment strategies for PFO repair without implantable devices to address these clinical concerns.
This technology is a repair strategy that targets PFO, a major mechanism of embolic events, using a device-free, localized application of bipolar radiofrequency (RF) energy to the cardiac septal defect. Two RF delivery plates are loaded into a transcatheter system for safe and non-invasive access to the defect site. These plates hold the PFO membrane together during energy application to fuse the tissues between discs and are subsequently removed to allow the tissue to heal. This technology allows the closure of PFO cases without permanent implantation and reduces the risk associated with standard device-based repair.
Patent Pending US20220022935
IR CU19147
Licensing Contact: Jerry Kokoshka
