This technology is a stable topical film-forming triple polymer gel (FFP) that slowly releases selected active ingredients comprising anti-inflammatory or anti-microbial agents to treat wounds or acne upon topical application.
Common treatment modalities such as topical creams, ointments, and wound dressings fail to fully repair surface wound injuries due to variations in size, shape, location, and etiology. Topical products can easily rub off without a protective layer, occluding wounds may increase infection risk, and applying dressings to certain body areas often requires daily changes until healing is complete. While some current film-forming products and Band-Aids contain antibacterial agents, they also lack broad-spectrum antimicrobial efficacy. Thus, there exists a need for an antimicrobial wound care solution that supports healing and remains securely in place.
This technology describes a film-forming triple polymer (FFP) composition that can be customized with a variety of antimicrobials, emollients, preservatives, botanical agents, and wound healing agents. When used as a wound care product, this technology acts like a liquid bandage, forming a robust transparent film upon application to the skin that can be removed with robust washing with water. The anti-inflammatory, antimicrobial, and wound-healing agents incorporated into the composition are slowly released to the wound surface, helping to improve healing and reduce infections. Moisturizing and anti-irritant ingredients can be incorporated into the gel for cosmetic applications such as acne treatment.
This technology has been evaluated for initial antimicrobial efficacy against S. aureus, P. aeruginosa, MRSA, C. albicans, and P. acne using a diffusion well-plate method. Additionally, wound healing properties were determined in a rat wound model.
IR CU23358, CU21063, CU21289
Licensing Contact: Sara Gusik