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Liver
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Nucleic acid treatment of disease or disorders, including cancer and diseases of the liver. “Protective effect of LNA-anti-miR-132 therapy on liver fibrosis in mice” Mol Ther Nucleic Acids.
This technology has been validated with heart, liver, vasculature, skin, and bone organ models derived from the same stem cell line.
It is built based on an open source image-viewing platform that integrated proprietary advanced 3D segmentation algorithms for solid tumors (e.g., in lung, liver and lymph nodes) and also contains a database with tumor segmentation and measurement results.
Aspects of this technology has been validated in mouse models, demonstrating high-resolution and chemically informative assessment of glucose metabolism in various murine tissues including tumors, brain, intestine and liver.
Identification of exosome-derived biomarkers that predispose to PGD after other organ transplant (e.g. lung, liver). Identification of molecular targets to prevent or treat post-heart transplant PGD.