Low-cost microfluidic chip for time-resolved cryo-electron microscopyCU22182Low-cost PDMS microfluidic TR cryo-EM chip enables affordable, modular time-resolved protein studies with rapid spray-plunge vitrification.TagsAdsorptionBiosensorCryogenic electron microscopyInventorsJoachim FrankQiao LinXiangsong FengManagerKristin NeumanDepartmentsBiochemistryBiochemistry & Molecular BiophysicsMechanical EngineeringDivisionsColumbia University Medical Center ( CUMColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-02-16
Diagnostic mechanical mapping of cardiac rhythm using ultrasoundCU13088Ultrasound-based, noninvasive electromechanical mapping reveals cardiac arrhythmia origins at high frame rates for targeted treatment.TagsAtrial fibrillationBiomechanicsCardiologyInventorsElisa KonofagouJean ProvostManagerDovina QuDepartmentsBiomedical EngineeringBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMFu Foundation School of Engineering and Applied Science (SEAS)Release Date2014-09-16
Microfluidic device for time-resolved cryo-electron microscopyCU21075Microfluidic concentric-buffer device sharpens reaction-time distribution for time-resolved cryo-EM, improving temporal precision.Tags3D printingAdsorptionCryogenic electron microscopyInventorsJoachim FrankXiangsong FengManagerKristin NeumanDepartmentsBiochemistryMechanical EngineeringDivisionsColumbia University Medical Center ( CUMFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-02-17
Natural language processing tool for cognitive scoring in Alzheimer's Disease patientsCU25391NLP platform predicts MMSE scores from unstructured clinical notes, enabling retrospective cognitive assessment in Alzheimer’s patients.TagsEHealthElectronic health recordHigh-throughput screeningInventorsBetina Ross S IdnayChunhua WengFangyi ChenManagerJoan MartinezDepartmentsBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMColumbia University Medical Center (CUMC)Release Date2025-07-31
PDMS microfluidic chip for rapid time-resolved cryo-EMCU19167PDMS microfluidic chip automates rapid sample prep and loading for time-resolved cryo-EM, enabling intermediate-structure capture.TagsCryogenic electron microscopyDrug metabolismEmbryonic developmentInventorsJoachim FrankQiao LinSandip KaledhonkarManagerKristin NeumanDepartmentsBiochemistryBiochemistry & Molecular BiophysicsMechanical EngineeringDivisionsColumbia University Medical Center ( CUMColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-02-17
Periodic motion algorithm for ultrasound imaging of the heartbeat2442Non-invasive ultrasound-based heart imaging detects arrhythmias by comparing cycle-to-cycle structural changes, enabling automated electrical mapping.TagsBird anatomyCT scanCatheterInventorsElisa KonofagouJean ProvostManagerDovina QuDepartmentsBiomedical EngineeringBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMFu Foundation School of Engineering and Applied Science (SEAS)Release Date2009-04-10
Elasticity mapping technique for real-time treatment monitoringCU14378High-frame-rate elasticity imaging for real-time HIFU treatment monitoring, mapping lesions to prevent overtreatment and guide therapy.TagsAblationBeamformingFrame rateInventorsElisa KonofagouJean ProvostYi (Gary) HouManagerDovina QuDepartmentsBiomedical EngineeringBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-04-20
Bioinformatic algorithm for automated family history retrieval and enhanced clinical careCU16095Automates retrieval of family medical history from electronic records, building a precise family tree for targeted care.TagsAlgorithmBioinformaticsDatabaseInventorsDavid K. VawdreyFernanda PolubriaginofNicholas P. TatonettiManagerKristin NeumanDepartmentsBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMColumbia University Medical Center (CUMC)Release Date2016-06-27
Ultrasound-based imaging method for real-time detection of single-heartbeats2945Single-heartbeat ultrasound imaging with temporally-unequispaced acquisition enhances real-time, noninvasive detection of non-periodic cardiac events.TagsCardiac muscleCommon carotid arteryData acquisitionInventorsElisa KonofagouJean ProvostJianwen LuoManagerDovina QuDepartmentsBiomedical EngineeringBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMFu Foundation School of Engineering and Applied Science (SEAS)Release Date2014-09-15
Scheduling, tracking, and database platform for clinical trial managementCU16136IMPACT: a web-based platform unifying scheduling, tracking, and auditing for clinical trials to reduce attrition and improve outcomes.TagsClinical trialDatabaseHealth informaticsInventorsChunhua WengThomas BiggerYat SoManagerJoan MartinezDepartmentsBiomedical InformaticsHerbert and Florence Irving Center for Clinical ResearchMedicineDivisionsColumbia University Medical Center ( CUMColumbia University Medical Center (CUMC)Release Date2016-03-11
Real-time Electromechanical Wave ImagingCU13163Electromechanical Wave Imaging integrates ultrasound data to map unified heart electromechanical function for rapid, noninvasive cardiac assessment.TagsCT scanCardiac outputCardiologyInventorsElisa KonofagouJean ProvostManagerDovina QuDepartmentsBiomedical EngineeringBiomedical InformaticsDivisionsColumbia University Medical Center ( CUMFu Foundation School of Engineering and Applied Science (SEAS)Release Date2014-09-16
