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The Technology: Protein fragment that promotes growth and differentiation of brain cells. As neuroprogenitor cells can give rise to a variety of brain cell types, this protein fragment has been shown to promote differentiation into mature neurons, oligodendrocytes, astrocytes, and even cerebellar granule neurons.
This technology is a protein for the treatment of cardiac and coronary artery inflammation that can be used as a potential therapeutic approach for vascular conditions like Kawasaki disease (KD) and immune mediated myocarditis. This technology involves the use of a recombinant glycosylated protein, FSTL-1, as a biomarker and therapeutic target for Kawasaki disease (KD), for the treatment of cardiac and coronary artery inflammation. Treatment with the recombinant protein was observed to decrease cardiac and coronary artery inflammation via downregulation of the macrophage inflammatory response and decreasing inflammatory cell infiltrate.
By increasing the production yield, this technology has the potential to increase efficiency in protein production projects. This technology is a modified bacterial model for improved expression and production of proteins. However, these expression models often result in low protein yields of unstable proteins.