Graphene-based nanosensors for customizable analyte detection
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The graphene nanosensor has been tested and demonstrated high performance while monitoring insulin concentrations between 1 nM and 500 nM. “Real-time monitoring of insulin using a graphene field-effect transistor aptameric nanosensor” ACS Appl Mater Interfaces. “Real-time monitoring of insulin using a graphene aptameric nanosensor” 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS).
The Technology: Adaptable nanosensor for time-resolved detection and monitoring of biomolecular analyte. This technology is an aptamer-based graphene nanosensor that enables real-time detection and characterization of biomolecular interactions. Upon selective analyte enrichment and aptamer binding, the conductance of the graphene nanosensor changes and delivers an accurate and real-time electrical readout of the analyte activity.
This technology achieves membrane-free, continuous glucose monitoring by detecting miniscule changes in the conductance of graphene functionalized with a glucose sensitive polymer. Sensor for internal, continuous glucose monitoring. Current internal sensors used for continuous glucose monitoring in diabetic patients rely on physical barriers to isolate the glucose, making them less responsive and adaptive.
- 7Molecule
- 5Mass spectrometry
- 5Glucose
- 5Multiplexing
- 5DNA sequencing
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- 20Biology
- 15Biotechnology
- 3Biosensors
- 13Branches of biology
- 19Chemistry
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- 9Qiao Lin
- 5Kenneth Shepard
- 4Jingyue Ju
- 3Chuanjuan Tao
- 3Milan N. Stojanovic M.D.
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- 10Dovina Qu
- 9Greg Maskel
- 4Cynthia Lang
- 1Jerry Kokoshka
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- 9Mechanical Engineering
- 8Electrical Engineering
- 4Chemical Engineering/Applied Chemistry
- 3Medicine
- 2Applied Physics & Applied Math
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- 23Fu Foundation School of Engineering and Applied Science (SEAS)
- 4Columbia University Medical Center (CUMC)
- 1BD Diagnostics
- 1Faculty of the Arts & Sciences
- 1Fu Foundation School of Engineering and
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