Categories - Columbia Technology Ventures

1,852 results

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Autophagy activating nucleotide sequence for neurodegenerative disease treatment

CU23286

Dec 20, 2024 · This technology is a nucleotide sequence for amplifying the expression of WDFY3 gene or its encoded protein, Autophagy-Linked FYVE (ALFY), that can be used to promote protein aggregate clearance in neurodegenerative diseases.

Inventors: Ai Yamamoto, Katherine R. Croce

10Autophagy Drug discovery Gene

Kristin Neuman

Pathology & Cell Biology Physiology and Cellular Biophysics

Columbia University Medical Center (CUMC)

Lipid targets and biomarkers for ferroptosis

CU24174

Dec 20, 2024 · This technology identifies lipids that act as biomarkers and potential therapeutic targets for ferroptosis, the iron-dependent programmed cell death pathway involved in many diseases, including cancer and neurodegenerative disorders.

Inventors: Baiyu Qiu, Brent Stockwell

12Acyl group Apoptosis Biomarker

Joan Martinez

Biological Sciences

Faculty of the Arts & Sciences

Rapid assessment of T cell health for enhanced cancer immunotherapy

CU24313

Dec 18, 2024 · This technology is a rapid assessment platform that integrates biomaterials, imaging, and machine learning models to evaluate the functionality of T cells for therapeutic applications.

Inventors: Jia Guo, Lance Kam, Nicole Lamanna, Xin Wang

14Algorithm Assay Biomaterial

Dovina Qu

Biomedical Engineering Medicine Psychiatry

Columbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)