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This technology is a cell therapy method involving the administration of hematopoietic stem cells to prevent organ rejection in transplant patients. Unmet Need: Effective prevention of organ transplant rejection and failure Current organ transplantation methods often face significant challenges due to the immune system ... This technology proposes to modulate mitofusin-regulated microtubule acetylation for the treatment of peripheral neuropathy. Unmet Need: Therapeutic target for the treatment of peripheral neuropathies Mutations in Mitofusin-2 (MFN2) cause sensory loss in peripheral neuropathies like Charcot-Marie-Tooth Type 2A ... This technology is a CRISPR transposon-based system to generate genetic knockouts or introduce new functions in bacteria in situ. Unmet Need: CRISPR technology with high efficiency for treatment of disease Clustered regularly interspaced short palindromic repeats (CRISPR), along with a guide RNA and a Cas enzyme ...