Conditional knockout mouse model for the Phf6 geneCU22370A tissue-specific Phf6 conditional knockout mouse model for studying Börjeson-Forssman-Lehmann syndrome and hematologic cancers.TagsAcute myeloid leukemiaGeneHigh-throughput screeningInventorsAdolfo A. Ferrando M.D., Ph.D.Teresa Palomero VasquezManagerJoan MartinezDepartmentsPathologyInstitute for Cancer GeneticsDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2022-08-20
SUMO2 conjugation therapy for restoring cognitive function in Alzheimer's diseaseCU23265SUMO2-based biologic restores synaptic function and memory in Alzheimer's without reducing amyloid, enabling late-stage cognitive recovery.TagsAdjuvant therapyAmyloid betaBlood–brain barrierInventorsLuana Fioriti Ph.D.Ottavio ArancioPaul Edward FraserManagerJerry KokoshkaDepartmentsPathologyMortimer B. Zuckerman Mind Brain Behavior InstituteDivisionsColumbia University Medical Center (CUMC)Release Date2025-06-26
Treatment for Alzheimer's Disease-related memory lossCU13335Selective PDE4D inhibitors improve AD memory with fewer side effects, offering low-dose, targeted cognitive benefits.TagsAmyloid betaBrainCerebral cortexInventorsErnesto FedeleJos PrickaertsMauro FaManagerJerry KokoshkaDepartmentsPathologyDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2018-05-11
Use of intratracheally administered hyaluronic acid to ameliorate emphysema428Intratracheal hyaluronic acid protects elastic fibers, slowing lung disease progression and offering a prophylactic, elasticity-preserving therapy.TagsAortaArthritisAsthmaInventorsJerome CantorManagerSara GusikDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)
Restoration of retromer complex in neurodegenerative diseases via transcriptional regulatorCU18398Target CREB3L2-ATF4 complex to restore retromer function, slowing neurodegenerative progression in AD/PD.TagsDrug developmentEndosomeGeneInventorsClaudio Andre Gouveia Martins RoqueJimena BaleriolaUlrich HengstManagerJerry KokoshkaDepartmentsPathologyTaub InstituteDivisionsColumbia University Medical Center (CUMC)Release Date2023-03-03CollectionsSmall MoleculeCNS/Neurology
Preclinical models of angioimmunoblastic T-cell lymphoma for therapeutic investigationCU23322RhoA G17V-driven mouse model of angioimmunoblastic T-cell lymphoma enables translational drug screening and pathogenesis study.TagsCancer cellChemotherapyGene expressionInventorsAdolfo A. Ferrando M.D., Ph.D.Teresa Palomero VasquezManagerJoan MartinezDepartmentsPathologyInstitute for Cancer GeneticsDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2023-06-15CollectionsOncology
Small molecule inhibitor of cognitive impairment associated with neurodegenerative diseaseCU23096Small molecule minaprine analog targets 5-HT2B to curb cognitive/behavioral deficits in neurodegenerative diseases, including Alzheimer's.Tags5-HT receptor5-HT2B receptorAmyloid betaInventorsDaniel M. WattersonErica AcquaroneOttavio ArancioManagerJerry KokoshkaDepartmentsPathologyPharmacologyTaub InstituteDivisionsColumbia University Medical Center (CUMC)Feinberg School of MedicineRelease Date2025-04-10
BCL6 knockout mouse models of lymphoma developmentCU21195BCL6 knockout mice model lymphoma development and germinal center immunity, enabling in vivo studies of BCL6 function.TagsAlleleAntibodyCoding regionInventorsRiccardo Dalla-FaveraManagerJoan MartinezDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2021-02-10CollectionsOncology
Modified cell-penetrating ATF5 protein to inhibit cancer cell growthCU18385Modified ATF5 peptide blocks cancer survival proteins (CEBPB/CEBPD/CCDC6), inducing cancer cell death; potential targeted therapy.TagsBreast cancerCancerCell growthInventorsJames M. AngelastroLloyd Greene PhDXiaotian SunManagerJerry KokoshkaDepartmentsPathologyMolecular BiosciencesPathology & Cell BiologyDivisionsColumbia University Medical Center (CUMC)Release Date2019-08-02CollectionsOncology
High-affinity RAGE fusion proteins for treating RAGE-mediated pathologiesProxy35RAGE fusion proteins selectively block RAGE-ligand interactions, potentially reducing oxidative stress and inflammation in multiple diseases.TagsArteriosclerosisBiological half-lifeCardiovascular diseaseInventorsAdnan MjalliAnn Marie Schmidt M.D.David Mark Stern M.D.ManagerJerry KokoshkaDepartmentsPathologyDean's OfficeSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2018-10-20
Specific inhibition of caspase-2 activation for the treatment of neurodegenerative diseasesCU12019Membrane-penetrable hexapeptide selectively blocks caspase-2-RAIDD, halting neuron death for neurodegenerative therapies.TagsAmyotrophic lateral sclerosisCaspaseCell membraneInventorsCarol M. Troy MD, PhDManagerJerry KokoshkaDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2015-12-09
Natural extracts to treat or prevent neurological and neurodegenerative disorders1630High-concentration ginseng dammaranes inhibit amyloid-beta production, enabling synthetic, natural-derived treatments for neurodegenerative diseases.TagsAmyloid betaAmyotrophic lateral sclerosisApoptosisInventorsDonald William LandryShi-xian DengTae-Wan Kim Ph.D.ManagerJerry KokoshkaDepartmentsPathologyMedicineDivisionsColumbia University Medical Center (CUMC)Release Date2010-10-26
Protein fragment to promote neurogenesisCU13345Dominant-negative ATF5 fragment drives differentiation of neuroprogenitors into mature neurons and glial cells, enabling brain regeneration research.TagsAstrocyteCellular differentiationCentral nervous systemInventorsJames M. AngelastroLloyd Greene PhDManagerJerry KokoshkaDepartmentsPathologyMolecular BiosciencesDivisionsColumbia University Medical Center (CUMC)Release Date2025-01-13
TLX1 mouse model recapitulates clinical symptoms of T cell acute lymphoblastic leukemiaCU23147TLX1 transgenic mouse models human T-ALL, mirroring clinical progression to study pathogenesis, microenvironment, and drug responses.TagsAcute lymphoblastic leukemiaAneuploidyAortic dissectionInventorsAdolfo A. Ferrando M.D., Ph.D.Teresa Palomero VasquezManagerJoan MartinezDepartmentsPathologyInstitute for Cancer GeneticsDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2023-04-15CollectionsOncology
Therapeutic phosphodiesterase type 5 (PDE5) inhibitorsCU12089PDE5 inhibitors with a novel benzonaphthyridine scaffold cross the blood-brain barrier to enhance memory, aiding Alzheimer’s therapy.TagsAmyloid betaApoptosisBlood–brain barrierInventorsDonald William Landry MD, Ph.D.Jole FioritoOttavio Arancio MD, PhDManagerJerry KokoshkaDepartmentsPathologyMedicineDivisionsColumbia University Medical Center (CUMC)Release Date2024-01-04CollectionsSmall MoleculeCNS/Neurology
Conditional knockout mouse model to study genomic instability of BRCA1 mutationsCU23027Inducible BRCA1 exon 2 knockout mouse model to study BRCA1-related genomic instability, tumorigenesis, and therapy screening.TagsAblationAlleleBRCA1InventorsFoon Wu-baerRichard Baer Ph.D.ManagerJoan MartinezDepartmentsPathologyDivisionsCollege of Physicians and Surgeons (CUMCColumbia University Medical Center (CUMC)Release Date2022-10-10CollectionsOncologyWomen's Health
Unique human phenotype to define novel gene function for OCRL1CU22138Neuron-specific OCRL1 variant model reveals brain-focused mechanisms in Lowe syndrome; enables targeted therapies, diagnostics, drug screening.TagsCataractCell membraneCiliumInventorsBarbara CorneoCecilia SenaCharles LeDucManagerCynthia LangDepartmentsPathologyPediatricsRehabilitation & Regenerative MedicineDivisionsColumbia University Medical Center (CUMC)Release Date2023-03-03CollectionsRare DiseaseCNS/Neurology
Conditional mouse model for the BARD1 geneCU23026A conditional Bard1 mouse model enables tissue-specific gene knockout to study BRCA1/BARD1 cancer risk and therapy.TagsAlleleBRCA1Breast cancerInventorsFoon Wu-baerRichard Baer Ph.D.ManagerJoan MartinezDepartmentsPathologyDivisionsCollege of Physicians and Surgeons (CUMCColumbia University Medical Center (CUMC)Release Date2022-10-10CollectionsOncologyWomen's Health
Spatial sequencing platform for studying microbiome community structureCU16351A spatial metagenomics platform preserving microbial community structure for high-resolution sequencing and mapping microbe interactions.TagsAntibodyDNA sequencingFluorescence in situ hybridizationInventorsHarris WangRavi ShethManagerCynthia LangDepartmentsPathologySystems BiologyDivisionsColumbia University Medical Center (CUMC)Release Date2022-07-22CollectionsPlatform/Research Tool
Monoclonal Antibody Enhancing T Cell Reactivity in AIDS Treatments2842Monoclonal antibody boosts T cell reactivity, enhancing HIV/AIDS immunotherapy and broader immune responses.TagsAIDSAntibodyAntigenInventorsNicole Suciu-FocaManagerSara GusikDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2011-04-15
Diagnostic Testing of MUM-1, MUM-2 Chromosomal Abnormalities for Multiple Myleloma611Prognostic diagnostic method detects MUM-1/MUM-2 chromosomal rearrangements in multiple myeloma via DNA hybridization probes.TagsAntibodyChromosomal translocationChromosome 14InventorsRiccardo Dalla-favera M.D.ManagerJoan MartinezDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2010-05-18
Treatment for obesity and obesity-related diseasesCU13074Notch1 decoy therapy lowers liver glucose, fat, and insulin resistance, offering obesity, T2D, NAFLD, and cancer protection.TagsBlood sugar levelCancerCardiovascular diseaseInventorsDomenico Accili M.D.Jan KitajewskiUtpal PajvaniManagerCynthia LangDepartmentsPathologyMedicineDivisionsColumbia University Medical Center (CUMC)Naomi Berrie Diabetes CenterRelease Date2016-04-22
In vitro establishment of AIDS-related lymphoma cell lines2953In vitro AIDS-NHL cell lines (HBL-1, HBL-2, HBL-3) enable study of HIV-related lymphomagenesis and drug/antiviral responses.TagsB cellBone marrowDiseaseInventorsRiccardo Dalla-FaveraManagerJoan MartinezDepartmentsPathologyRelease Date2011-08-12
Mouse Model to Study Gene Cluster in Chronic Lymphocytic Leukemia and Cell Cycle Progression2807Conditional knockout mouse model deleting DLEU2/miR-15a/16-1 cluster recapitulates full human CLL pathogenesis for research and therapy testing.TagsApoptosisB cellCancer cellInventorsRiccardo Dalla-FaveraUlf KleinManagerJoan MartinezDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2011-06-24
Specialized diet for enhanced cancer treatmentCU21118Amino acid-restricted diet enhances chemotherapy/radiation efficacy by selectively targeting cancer cells while maintaining energy needs.TagsAmino acidChemotherapyGliomaInventorsBrent StockwellDominique HigginsJeffrey BruceManagerJerry KokoshkaDepartmentsPathologyBiological SciencesNeurological SurgeryDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Faculty of the Arts & SciencesRelease Date2020-11-05CollectionsOncology
Automated pathological imaging and detection of cancerCU20175High-speed OCT with AI enables automated, high-resolution breast tissue analysis for rapid cancer detection and margin assessment.TagsAnatomyArtificial intelligenceBreast cancerInventorsChristine P. HendonDiana MojahedHanina HibshooshManagerDovina QuDepartmentsPathologyBiomedical EngineeringElectrical EngineeringDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-09-22CollectionsOncologyMedical DeviceWomen's Health
Overcoming drug resistance in relapsed T-ALL patientsCU13051Mutated NT5C2 inhibitors counteract nucleoside-analog resistance in relapsed T-ALL, enabling first-line therapies and broader applicability.TagsAcute lymphoblastic leukemiaAcute myeloid leukemiaCancer cellInventorsAdolfo A. Ferrando M.D., Ph.D.Raul RabadanTeresa Palomero VasquezManagerJoan MartinezDepartmentsPathologyBiomedical InformaticsInstitute for Cancer GeneticsDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2013-09-03
A preclinical Gba p.E326K mouse model for precision-medicine researchCU23198CRISPR-generated Gba p.E326K mouse model for Gaucher, PD, and DLB research; enables biomarker discovery and preclinical drug testing.TagsBiomarkerCognitive deficitDementiaInventorsLorraine ClarkManagerKristin NeumanDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2023-03-17CollectionsCNS/NeurologyPlatform/Research Tool
Mouse line as a model for Peripheral T-cell Lymphoma with GATA3+ featuresCU23321Mouse model for Vav1-Myof1-driven Peripheral T-cell Lymphoma (GATA3+) enabling targeted therapy screening and pathogenesis study.TagsCD4CarcinogenesisGenetic testingInventorsAdolfo A. Ferrando M.D., Ph.D.Teresa Palomero VasquezManagerJoan MartinezDepartmentsPathologyInstitute for Cancer GeneticsDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2023-06-15CollectionsOncology
Phosphoinositide modulation for treatment of neurodegenerative diseases2240Modulating phosphoinositide lipids to reduce amyloid-β toxicity; potential therapeutics for Alzheimer's and other neurodegenerative diseases.TagsAmyloid betaDown syndromeHigh-throughput screeningInventorsDiego BermanGilbert Di PaoloLaura Beth Johnson McIntireManagerJerry KokoshkaDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2018-10-20
Inhibition of circadian regulation or mTOR complex increases immunity against bacterial infectionCU16116Inhibiting mTORC2 and adjusting circadian rhythm enhances immunity, offering host-targeted therapy against multidrug-resistant bacterial infections.TagsAntimicrobial resistanceApoptosisCancerInventorsJulie CanmanMatthew UlgheraitMichele M. Shirasu-HizaManagerKristin NeumanDepartmentsPathologyGenetics & DevelopmentDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2017-05-05
AVPR1A blockade for the treatment of social isolation-induced anxiety in femalesCU21294AVPR1A-targeted therapy reduces social isolation-induced anxiety in females by modulating AVP signaling in the amygdala.TagsAmygdalaEstrogen receptorGenetically modified mouseInventorsLori M. ZeltserMarie Louise Pascale Jocelyna FrancoisManagerKristin NeumanDepartmentsPathologyPediatricsDivisionsCollege of Physicians and Surgeons (CUMCColumbia University Medical Center (CUMC)Release Date2024-08-22
Conditional Ctip-co mouse strain for studying DNA resectionCU23028A conditional CtIP knockout mouse model enables full inactivation studies of DNA resection, cancer development, and therapy screening.TagsAlleleCancerCarcinogenesisInventorsFoon Wu-baerRichard Baer Ph.D.ManagerJoan MartinezDepartmentsPathologyDivisionsCollege of Physicians and Surgeons (CUMCColumbia University Medical Center (CUMC)Release Date2022-10-10CollectionsOncology
Transgenic T cells for Lymphoblastic Leukemia1894Transgenic CUTLL1 T-ALL model enables testing NOTCH1-targeted therapies and gamma-secretase inhibitors for pediatric leukemia.TagsCancerChromosomal translocationDrug developmentInventorsAdolfo A. FerrandoJulia L. Glade BenderTeresa Palomero VasquezManagerJoan MartinezDepartmentsPathologyInstitute for Cancer GeneticsPediatricsDivisionsColumbia University Medical Center (CUMC)Release Date2011-05-12
Cancer Treatment with Notch-based Fusion Proteins1530Notch-receptor fusion biologics inhibit tumor angiogenesis and differentiation, offering standalone or combination cancer therapy with novel delivery.TagsAngiogenesisBevacizumabBlood vesselInventorsCarrie ShawberJan KitajewskiYasuhiro FunahashiManagerSara GusikDepartmentsPathologyObstetrics & GynecolDivisionsColumbia University Medical Center (CUMC)Release Date2009-05-20
Cysteine protease inhibitors to treat traumatic brain injury and Alzheimer's diseaseCU12222Potent, selective epoxide-based calpain-1 inhibitors ( NYC438/ NYC488 ) restore memory and synaptic function in AD and TBI models.TagsCysteine proteaseEnzyme inhibitorEpoxideInventorsGregory R.J. ThatcherIsaac SchieferMauro FaManagerJerry KokoshkaDepartmentsPathologyMedicinal Chemistry & PharmacognosyDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2019-04-29CollectionsSmall MoleculeCNS/Neurology
Method to target valproic acid treatment for the negative symptoms of psychiatric disorders using pharmacogenomicsCU15242Personalized valproic acid therapy: predict response via circulating proline and COMT genotype to target treatment and reduce negative symptoms.TagsBipolar disorderCatechol-O-methyltransferaseEnzymeInventorsCatherine ClellandManagerKristin NeumanDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2016-09-09
Stem cells and stem cell-derived neurons as a model for studying Alzheimer's Disease2917Renewable mouse embryonic stem cell–derived neurons model Alzheimer's pathology for high-throughput drug screening and target discovery.TagsAmyloid betaAssayDrug discoveryInventorsLaura Beth Johnson McIntireNatalie LandmanTae-Wan Kim Ph.D.ManagerJerry KokoshkaDepartmentsPathologyNeurobiologyDivisionsCollege of Physicians and Surgeons (CUMCColumbia University Medical Center (CUMC)Release Date2016-04-22
BCL-6 gene and antibody for lymphoma diagnosis381Targeted BCL-6 biomarker-based lymphoma diagnostics and companion immunotherapies to improve accuracy and reduce treatment side effects.TagsAntibodyAssayB cellInventorsRaju S. K. ChagantiRiccardo Dalla-favera M.D.ManagerJoan MartinezDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2010-11-18
Thiazolide treatment for Alzheimer's and other neurodegenerative diseasesCU18297FDA-approved antivirals crossing blood-brain barrier may lower tau protein, offering potential Alzheimer's and tauopathy therapy.TagsAblationAntiviral drugBlood–brain barrierInventorsGina FinanTae-Wan Kim Ph.D.ManagerJerry KokoshkaDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2019-08-01CollectionsSmall MoleculeCNS/Neurology
Methods for diagnosis and treatment of neuropsychiatric disorders2789Genetic GCH1 assay guides diagnosis and personalized treatment for schizophrenia and related neuropsychiatric disorders.TagsAlleleAssayBipolar disorderInventorsCatherine ClellandManagerKristin NeumanDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2018-09-28
Truncated ATF5, CEBPB, and CEBPD inhibitors for effective cancer treatmentCU21274Short cell-penetrating truncated inhibitors target ATF5/CEBPB/CEBPD, suppressing cancer survival across tumor types.TagsBreast cancerCancerCancer cellInventorsJames M. AngelastroLloyd Greene PhDQing ZhouManagerJerry KokoshkaDepartmentsPathologyMolecular BiosciencesPathology & Cell BiologyDivisionsColumbia University Medical Center (CUMC)Release Date2023-10-31CollectionsOncology
Osteocalcin as a treatment to enhance male fertility2685Osteocalcin from bone boosts male fertility by increasing testosterone, testis size, sperm motility, offering cheaper infertility therapy.TagsAssisted reproductive technologyBiomarkerErectile dysfunctionInventorsGerard KarsentyPatricia DucyManagerJerry KokoshkaDepartmentsPathologyGenetics & DevelopmentDivisionsColumbia University Medical Center (CUMC)Release Date2016-05-27
Therapeutic activation of circadian-regulated autophagy to increase lifespan and healthspanCU21009Therapeutically activates circadian-regulated autophagy to extend lifespan and healthspan without dieting, via ULK1/LC3/AMPK/S6K targets.TagsAtherosclerosisAutophagyCalorie restrictionInventorsJulie CanmanMatthew UlgheraitMichele M. Shirasu-HizaManagerKristin NeumanDepartmentsPathologyGenetics & DevelopmentDivisionsColumbia University Medical Center (CUMC)Release Date2020-07-17CollectionsCNS/Neurology
Recombinant ILT3 protein-produced antibodies for immunotherapy treatment of cancerCU15207Engineered anti-ILT3 antibodies enable targeted cancer immunotherapy, modulating myeloid signals and enhancing immune blockade.TagsAcute myeloid leukemiaAllotransplantationAntibodyInventorsGeorge Vlad Ph.D.Nicole Suciu-FocaZheng XuManagerSara GusikDepartmentsPathologyDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2023-03-08CollectionsOncology
Restoring synaptic function to prevent and treat neurodegenerative diseasesCU18018Tech targets UBE3A to restore synaptic function, offering disease-modifying treatment for AD and other neurodegenerative disorders.TagsAmyloid betaEnzymeGene expressionInventorsRoger Lefort PhDManagerKristin NeumanDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2019-01-25CollectionsCNS/Neurology
PDE5 inhibitor for Alzheimer's treatment2439A brain-penetrant PDE5 inhibitor enhances cGMP signaling, reduces amyloid, and supports synaptic plasticity in Alzheimer’s models.TagsAmyloid betaAmyloid plaquesBlood–brain barrierInventorsDonald William Landry MD, Ph.D.Ottavio Arancio MD, PhDShi-xian DengManagerJerry KokoshkaDepartmentsPathologyMedicineDivisionsColumbia University Medical Center (CUMC)Release Date2025-12-18
Antibody for probing the guanine biosynthesis pathwayCU14353Monoclonal anti-IMPDH2 antibody labels and studies guanine biosynthesis, enabling cancer cell phenotyping and potential diagnostics/therapy.TagsAntibodyAntibody-drug conjugateBiosynthesisInventorsGeorge VladMuyang LiNicole Suciu-FocaManagerSara GusikDepartmentsPathologyInstitute for Cancer GeneticsDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2014-12-31
Pharmacogenetic treatment of psychiatric symptoms through L-proline transport inhibitorsCU17320Pharmacogenetic proline transport inhibitors tailor psychiatric treatment by COMT genotype, predicting response and targeting negative symptoms.TagsAnxiety disorderAssayBipolar disorderInventorsCatherine ClellandJames D. ClellandManagerKristin NeumanDepartmentsPathologyDivisionsColumbia University Medical Center (CUMC)Release Date2018-07-16
siRNA Delivery to Inhibit Tumor Growth in the Central Nervous System1982Convection-enhanced CNS delivery of cell-penetrating siRNA suppresses tumor growth by targeted gene silencing.TagsApoptosisBlood–brain barrierCentral nervous systemInventorsAndrew F. DucruetCarol M. Troy MD, PhDE. Sander Connolly, Jr. M.D.ManagerJerry KokoshkaDepartmentsPathologyNeurological SurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2009-05-20