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Fu Foundation School of Engineering and

21 results

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Thermostable microring modulators for use in optical devices

CU14094

Thermostable silicon microring modulators with mean-power feedback stabilize resonance, enabling compact, low-power, high-speed optical links.

Tags: Energy
Integrated circuit
Laser
Inventors: Andrew Knights
Dylan Logan
Keren Bergman
Manager: Greg Maskel
Departments: Electrical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2018-04-13

Rapid, highly sensitive multiplexed viral detection with nanopores

CU21160

Ultrafast, amplification-free nanopore-based single-molecule assay for multiplexed viral detection (SARS-CoV-2) and antibodies.

Tags: Antibody
Antigen
Assay
Inventors: Chuanjuan Tao
James J. Russo
Jingyue Ju
Manager: Cynthia Lang
Departments: Chemical Engineering/Applied Chemistry
Chemistry
Genome Center
Divisions: Fu Foundation School of Engineering and
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2023-07-20

Synthesis method for high purity graphene

CU21336

A controlled, automated CVD method producing ultra-pure graphene with faster, lower-temperature synthesis for scalable, high-performance films.

Tags: Chemical vapor deposition
Graphene
Heterojunction
Inventors: Christopher DiMarco
James Hone
Manager: Dovina Qu
Departments: Mechanical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2021-05-26

High-yield production of macroscopic 2D materials

CU20156

Ultra-flat gold tape enables scalable, high-yield production of macroscopic 2D materials for electronics and quantum tech.

Tags: Graphene
Metal
Monolayer
Inventors: Fang Liu
James Hone
Jue Wang
Manager: Dovina Qu
Departments: Chemistry
Mechanical Engineering
Divisions: Fu Foundation School of Engineering and
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2020-05-13

Accurate and efficient speech signal processing method for artificial intelligence

CU22076

Pitch-synchronous speech processing enhances AI accuracy with concise, human-like representations, reducing noise and computation.

Tags: Artificial intelligence
Speech recognition
Timbre
Inventors: Julian Chengjun Chen
Manager: Dovina Qu
Departments: Applied Physics & Applied Math
Divisions: Fu Foundation School of Engineering and
Release Date: 2021-10-11

A low-cost, robust method for automatically tuning a coupled resonator and laser for high-speed photonics applications

CU13185

Automatic wavelength locking and thermal stabilization of silicon microring resonators with dithering signals for scalable, energy-efficient photonics.

Tags: Biosensor
CMOS
Dither
Inventors: Keren Bergman
Kishore Padmaraju
Manager: Greg Maskel
Departments: Electrical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2019-04-15

Pitch-synchronous method for speech encoding and decoding

CU16133

Pitch-synchronous speech parameterization enables natural, tonal-language aware recognition and synthesis, improving realism and accuracy.

Tags: Acoustics
Phonation
Speech coding
Inventors: Julian Chengjun Chen
Manager: Dovina Qu
Departments: Applied Physics & Applied Math (APAM)
Divisions: Fu Foundation School of Engineering and
Release Date: 2016-03-11

Therapeutic agents for viral infections using nucleoside and nucleotide analogues

CU25201

Modified Remdesivir analogs with dual prodrugs block RNA virus replication, bypass proofreading, outperform current antivirals.

Tags: Antiviral drug
Dengue virus
Encephalitis
Inventors: Chuanjuan Tao
Irina Morozova
James J. Russo
Manager: Cynthia Lang
Departments: Biomedical Informatics
Chemical Engineering/Applied Chemistry
Genome Center
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2026-01-08

Power efficient phase shifters for near-IR wavelengths

CU18268

Power-efficient near-IR phase shifter using excitonic 2D materials (TMDs) for high index change with low loss.

Tags: Chalcogenide
Energy
Modulation
Inventors: Dmitri N. Basov
Ipshita Datta
James Hone
Manager: Greg Maskel
Departments: Electrical Engineering
Materials Science and Engineering
Mechanical Engineering
Divisions: Fu Foundation School of Engineering and
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2019-10-25

Graphene-based optical modulator for low-power, high-sensitivity cryogenic data transmission

CU16109

Graphene-based optical modulator enables ultra-low-power, high-sensitivity cryogenic-to-room-temperature data links using 1 mV signals.

Tags: Crosstalk
Data link
Electric power transmission
Inventors: Christopher Phare
Keren Bergman
Michal Lipson
Manager: Greg Maskel
Departments: Electrical and Computer Engineering
Electrical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2024-11-08

Integrated silicon photonic band interleaver

CU23236

Integrated silicon photonic band interleaver enables tunable, high-FSR spectral multiplexing for on-chip data communication.

Tags: Compact space
Error correction code
Integrated circuit
Inventors: Anthony Rizzo
Asher Novick
Keren Bergman
Manager: Greg Maskel
Departments: Electrical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2024-02-01

Strategy to attack SARS-CoV-2 and other coronaviruses

CU20241

Nucleotide-analogue viral inhibitors target coronavirus polymerases, offering selective, mutation-resistant, broad-spectrum COVID-19 therapies.

Tags: Coronavirus
DNA sequencing
Nucleotide
Inventors: James J. Russo
Jingyue Ju
Shiv Kumar
Manager: Cynthia Lang
Departments: Chemical Engineering/Applied Chemistry
Chemistry
Genome Center
Divisions: Fu Foundation School of Engineering and
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2020-01-31
Collections: Small Molecule

A universal method to interrogate genome-wide methylation patterns

CU13219

A universal, unbiased methylation assay using DNMTs and AdoMet analogues enables genome-wide, single-base methylation profiling with low DNA input.

Tags: Automation
Carcinoma
CpG site
Inventors: Jingyue Ju
Timothy Bestor
Xiaoxu Li
Manager: Cynthia Lang
Departments: Chemical Engineering/Applied Chemistry
Genetics & Development
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2015-12-09

Whole methylome sequencing at the single molecule level

CU16353

Single-molecule, targeted methylome sequencing detects methylation types with high sensitivity, enabling precise epigenetic profiling and diagnostics.

Tags: Chemistry
DNA methylation
Epigenetics
Inventors: James J. Russo
Jingyue Ju
Steffen Jockusch
Manager: Cynthia Lang
Departments: Chemical Engineering/Applied Chemistry
Chemistry
Genetics & Development
Divisions: Fu Foundation School of Engineering and
Columbia University Medical Center (CUMC)
Faculty of the Arts & Sciences
Release Date: 2020-12-24

Spectrogram software for yielding high-definition timbre spectra

CU18357

Software that fully separates pitch and timbre to deliver high-definition, reliable spectra for speech analysis and voice tech.

Tags: Algorithm
Formant
Spectral density
Inventors: Julian Chengjun Chen
Manager: Dovina Qu
Departments: Applied Physics & Applied Math
Divisions: Fu Foundation School of Engineering and
Release Date: 2018-05-24

Focal Sweep for Space-time Depth Recovery and User Interactive Refocusing

CU14239

Focal sweep captures space-time depth, enabling interactive refocusing and all-in-focus images from a single sweep.

Tags: Camera lens
Closed-circuit television
Computer science
Inventors: Changyin Zhou
Daniel Miau
Shree Kumar Nayar
Manager: Greg Maskel
Departments: Computer Science
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2014-11-19

DNA and RNA sequencing using ion sensing and nucleotide reversible terminators

2864

Ion-sensing sequencing with reversible terminators enables cheaper, high-throughput DNA/RNA sequencing without fluorescent labels.

Tags: Functional group
Ion
Medication
Inventors: James J. Russo
Jingyue Ju
Lin Yu
Manager: Cynthia Lang
Departments: Chemical Engineering/Applied Chemistry
Genome Center
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2015-04-13

Polymeric nanofiber scaffold for cartilage tissue engineering

CU19168

Electroactive polymeric nanofiber scaffold with graphite enhances chondrocyte growth, matrix deposition, and cartilage graft integration.

Tags: 3D printing
Autotransplantation
Biomedical engineering
Inventors: Christopher Zachary Mosher
Helen Lu
James Hone
Manager: Joan Martinez
Departments: Biomedical Engineering
Mechanical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2020-09-17

DNA sequencing by synthesis with nucleotide analogues and Raman detection

CU16261

Fluorophore-free DNA sequencing by synthesis using nucleotide analogues and Raman detection for cost-effective, high-throughput reads.

Tags: Biology
DNA sequencing
Fluorophore
Inventors: Irina Morozova
James J. Russo
Jingyue Ju
Manager: Cynthia Lang
Departments: Biomedical Informatics
Chemical Engineering/Applied Chemistry
Chemistry
Divisions: Fu Foundation School of Engineering and
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2016-03-28

Optical Packet Buffer System is Modular, Scalable and Extensible

M07-011

Modular, scalable optical buffer for packet switching enables independent read/write, FIFO/LIFO prioritization, with extensible, loss-minimizing design.

Tags: FIFO (computing and electronics)
Internet
Network packet
Inventors: Assaf Shacham
Benjamin A. Small
Keren Bergman
Manager: Greg Maskel
Departments: Electrical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2006-08-25

DNA-based high spatial resolution thermometer based on temperature dependent fluorescence

M11-123

DNA-based high-resolution thermometer uses fluorescence in DNA strands for real-time, spatial temperature mapping with 0.1°C precision.

Tags: DNA sequencing
Fluorescence
Integrated circuit
Inventors: Haig Norian
John Ioannis Kymissis
Kenneth Shepard
Manager: Greg Maskel
Departments: Electrical Engineering
Divisions: Fu Foundation School of Engineering and
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2014-10-14