Knock-in mouse lines to target striatal projection neurons and dopaminergic neuronsCU26031Knock-in Cre/FlpO mice precisely target striatal projection and dopaminergic neurons for cell-type specific neuroscience research.TagsAdenosineAdenosine A2A receptorBasal gangliaInventorsRui CostaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-11-07
A2a-FlpO mouse model for neuroscience studiesCU26036Precise, cell-type specific A2a-FlpO knock-in mice enable orthogonal D1/D2 dopaminergic studies in basal ganglia circuits.TagsBasal gangliaBehavioral neuroscienceCombinatoricsInventorsRui CostaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-11-13
D1-Cre knock-in mouse for genetic targeting of basal ganglia circuitsCU26035CRISPR knock-in D1-Cre mouse ensures precise, endogenous D1 neuron targeting in basal ganglia for targeted circuit studies.TagsBasal gangliaCre recombinaseDopamineInventorsRui CostaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-11-13
Efficient, generalizable brain-computer interface for neural feedback controlCU23225Generalizable, unsupervised brain-computer interface: invariant neural dynamics enable context-free motor control without per-task calibration.TagsBrain–computer interfaceCyborgMotor controlInventorsJose CarmenaRui CostaVivek AthalyeManagerKristin NeumanDepartmentsMortimer B. Zuckerman Mind Brain Behavior InstituteNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-07-06
Targeted knock-in mouse line for studying neuropsychiatric diseaseCU26034A knock-in mouse line enabling precise A2a-expressing neuron targeting in basal ganglia for neuropsychiatric research and drug validation.TagsAdenosine A2A receptorBasal gangliaCre recombinaseInventorsRui CostaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-11-13
Hip implant for securement to the femur of a subject with applications to other jointsCU23044Patient-specific, minimally invasive reversible hip implant that anchors without bone penetration; applicable to other joints.TagsBoneBone remodelingFemurInventorsAlexander KellElias IssaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2024-01-02CollectionsMedical Device
A mouse model expressing recombinase in dopamine transporter-positive neuronsCU26033Precise FlpO recombination in dopamine transporter neurons via CRISPR knock-in, enabling targeted dopaminergic research.TagsBasal gangliaDopamineDopamine transporterInventorsRui CostaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-11-07
Screwless, patient-specific cranial implant for neural accessCU22306Screwless, patient-specific 3D-printed titanium cranial implants provide broad neural access, improve stability, and reduce invasiveness.Tags3D printingBiomechanicsBoneInventorsAlexander KellElias IssaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2024-12-30
IL-6 Inhibitor for acute inflammatory disordersCU24063Synthetic peptide suppressing IL-6 production to treat acute inflammatory conditions like sepsis, endotoxin shock, and cytokine storms.TagsAntibioticBiopharmaceuticalCytokineInventorsKazuya MasudaMoriya TsujiZizhang ShengManagerKristin NeumanDepartmentsAaron Diamond AIDS Research Center (ADARC)MedicineNeuroscienceDivisionsZuckerman Mind Brain Behavior InstColumbia University Medical Center (CUMC)Release Date2025-08-21
Anxa1-Cre mouse for selective modeling of dopaminergic neurons in Parkinson's diseaseCU26032Anxa1-Cre mouse enables precise manipulation of a vulnerable dopaminergic neuron subtype to study early Parkinson’s motor deficits.TagsBiomarkerCausalityCre recombinaseInventorsRui CostaManagerKristin NeumanDepartmentsNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2025-11-07
Functional tagging of neurons for further integrative analysisCU24343In vivo activity-tagging of activated neurons enables high-throughput collection for downstream transcriptomic analysis and function-genome mapping.TagsTranscriptomeInventorsAttila LosonczyBoaz NutkovichDahlia KushinskyManagerKristin NeumanDepartmentsBrain SciencesNeuroscienceDivisionsZuckerman Mind Brain Behavior InstColumbia University Medical Center (CUMC)Release Date2025-12-01
Cup holder for studying head-fixed miceCU21353Cup-height perch improves forelimb mobility in head-fixed mice, enabling complex motor learning studies with existing tools.TagsElectrophysiologyMotor controlMotor learningInventorsAlice C. MosbergerHelio RodriguesInes Rodrigues-VazManagerKristin NeumanDepartmentsMortimer B. Zuckerman Mind Brain Behavior InstituteNeuroscienceDivisionsZuckerman Mind Brain Behavior InstRelease Date2021-06-11
