Divisions
Zuckerman Mind Brain Behavior Inst
View all technologies
Knock-in mouse lines to target striatal projection neurons and dopaminergic neurons
CU26031
Knock-in Cre/FlpO mice precisely target striatal projection and dopaminergic neurons for cell-type specific neuroscience research.
Tags
Adenosine
Adenosine A2A receptor
Basal ganglia
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-07
A2a-FlpO mouse model for neuroscience studies
CU26036
Precise, cell-type specific A2a-FlpO knock-in mice enable orthogonal D1/D2 dopaminergic studies in basal ganglia circuits.
Tags
Basal ganglia
Behavioral neuroscience
Combinatorics
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-13
D1-Cre knock-in mouse for genetic targeting of basal ganglia circuits
CU26035
CRISPR knock-in D1-Cre mouse ensures precise, endogenous D1 neuron targeting in basal ganglia for targeted circuit studies.
Tags
Basal ganglia
Cre recombinase
Dopamine
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-13
Efficient, generalizable brain-computer interface for neural feedback control
CU23225
Generalizable, unsupervised brain-computer interface: invariant neural dynamics enable context-free motor control without per-task calibration.
Tags
Brain–computer interface
Cyborg
Motor control
Inventors
Jose Carmena
Rui Costa
Vivek Athalye
Manager
Kristin Neuman
Departments
Mortimer B. Zuckerman Mind Brain Behavior Institute
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-07-06
Targeted knock-in mouse line for studying neuropsychiatric disease
CU26034
A knock-in mouse line enabling precise A2a-expressing neuron targeting in basal ganglia for neuropsychiatric research and drug validation.
Tags
Adenosine A2A receptor
Basal ganglia
Cre recombinase
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-13
Hip implant for securement to the femur of a subject with applications to other joints
CU23044
Patient-specific, minimally invasive reversible hip implant that anchors without bone penetration; applicable to other joints.
Tags
Bone
Bone remodeling
Femur
Inventors
Alexander Kell
Elias Issa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2024-01-02
Collections
Medical Device
A mouse model expressing recombinase in dopamine transporter-positive neurons
CU26033
Precise FlpO recombination in dopamine transporter neurons via CRISPR knock-in, enabling targeted dopaminergic research.
Tags
Basal ganglia
Dopamine
Dopamine transporter
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-07
Screwless, patient-specific cranial implant for neural access
CU22306
Screwless, patient-specific 3D-printed titanium cranial implants provide broad neural access, improve stability, and reduce invasiveness.
Tags
3D printing
Biomechanics
Bone
Inventors
Alexander Kell
Elias Issa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2024-12-30
IL-6 Inhibitor for acute inflammatory disorders
CU24063
Synthetic peptide suppressing IL-6 production to treat acute inflammatory conditions like sepsis, endotoxin shock, and cytokine storms.
Tags
Antibiotic
Biopharmaceutical
Cytokine
Inventors
Kazuya Masuda
Moriya Tsuji
Zizhang Sheng
Manager
Kristin Neuman
Departments
Aaron Diamond AIDS Research Center (ADARC)
Medicine
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Columbia University Medical Center (CUMC)
Release Date
2025-08-21
Anxa1-Cre mouse for selective modeling of dopaminergic neurons in Parkinson's disease
CU26032
Anxa1-Cre mouse enables precise manipulation of a vulnerable dopaminergic neuron subtype to study early Parkinson’s motor deficits.
Tags
Biomarker
Causality
Cre recombinase
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-07
Functional tagging of neurons for further integrative analysis
CU24343
In vivo activity-tagging of activated neurons enables high-throughput collection for downstream transcriptomic analysis and function-genome mapping.
Tags
Transcriptome
Inventors
Attila Losonczy
Boaz Nutkovich
Dahlia Kushinsky
Manager
Kristin Neuman
Departments
Brain Sciences
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Columbia University Medical Center (CUMC)
Release Date
2025-12-01
Cup holder for studying head-fixed mice
CU21353
Cup-height perch improves forelimb mobility in head-fixed mice, enabling complex motor learning studies with existing tools.
Tags
Electrophysiology
Motor control
Motor learning
Inventors
Alice C. Mosberger
Helio Rodrigues
Ines Rodrigues-Vaz
Manager
Kristin Neuman
Departments
Mortimer B. Zuckerman Mind Brain Behavior Institute
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2021-06-11
