Columbia Technology Ventures
Tags
Neoplasm
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Scalable, reproducible, immune-intact tumor organoid co-culture platform
CU24328
Patient-derived immune-intact tumor organoids enable scalable, reproducible co-culture for personalized immunotherapy and drug screening.
Tags
Neoplasm
Biomarker
Biotechnology
Inventors
David Cohen
Joel T. Gabre MD
Manager
Joan Martinez
Departments
Herbert Irving Comprehensive Cancer Center
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2026-01-08
Selective COX-2 radioligands for PET imaging of neuroinflammation
CU19254
Fluorine-18 COX-2 PET radioligands enable noninvasive imaging of neuroinflammation with higher affinity and broad clinical reach.
Tags
Neoplasm
Agonist
COX-2 inhibitor
Inventors
Akiva Mintz
J. John Mann
J.S. Dileep Kumar
Manager
Jerry Kokoshka
Departments
Psychiatry
Radiology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2025-12-17
VRK2 kinase inhibitors for enhanced cancer immunotherapy
CU21245
VRK2 inhibitors boost PD-1 therapy by targeting downstream signaling, enhancing T cell activation and tumor clearance.
Tags
Neoplasm
Adenocarcinoma
Bladder cancer
Inventors
Adam Mor
Manager
Cynthia Lang
Departments
Rheumatology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-12-17
Cross-platform radiomics toolkit for predictive cancer imaging
Proxy116
Cross-platform radiomics toolkit automates standardized 2D/3D cancer imaging analysis for reproducible, scalable biomarker discovery.
Tags
Neoplasm
Batch processing
Cross-platform software
Inventors
Christos Davatzikos
Despina Kontos
Manager
Joan Martinez
Departments
Radiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-12-04
Dynein inhibition for enhanced anti-tumor cytotoxicity in solid tumors
CU24341
Dynein inhibition boosts natural killer cell cytotoxicity against solid tumors, enhancing immunotherapy efficacy across diverse microenvironments.
Tags
Neoplasm
Adjuvant
Cytotoxic T cell
Inventors
Jordan S. Orange MD, PhD
Manager
Jerry Kokoshka
Departments
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-11-20
In vivo internalizing RGD peptide production for enhanced treatment of solid tumors
CU25033
In vivo iRGD plasmid drives tumor penetration, reducing immunosuppression; co-administers with CAR-T/ therapies for enhanced efficacy.
Tags
Neoplasm
Angiogenesis
Cancer immunotherapy
Inventors
Kazuki N. Sugahara
Norio Miyamura
Manager
Jerry Kokoshka
Departments
Surgery
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-11-20
Coherent factor-based passive cavitation mapping for monitoring of focused ultrasound treatment
CU22079
Coherent factor-based passive acoustic mapping enables real-time, high-resolution, low-cost monitoring of transcranial focused ultrasound treatment.
Tags
Neoplasm
Ablation
Acoustics
Inventors
Elisa Konofagou
Sua Bae
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-11-07
Targeting senescent cells for the treatment of photoaging and melanoma
CU25349
Senescent-cell–targeting therapy reverses photoaging and slows melanoma, offering dual cosmetic and oncologic benefits.
Tags
Neoplasm
Cellular senescence
Chemotherapy
Inventors
Danial Khayatan
Rolando Perez-Lorenzo
Manager
Jerry Kokoshka
Departments
Dermatology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-10-09
Dual targeting of epigenetically amplified lymphomas via epigenetic modifiers and immune checkpoint inhibition
CU24177
Dual-targeted PMBCL therapy: epigenetic reprogramming plus anti-PD-1 immune blockade enhances immunogenicity and overcomes resistance.
Tags
Neoplasm
Cancer
Cancer immunotherapy
Inventors
Jennifer Amengual
Seda Serra Tolu
Manager
Kristin Neuman
Departments
Medicine
Medicine - Hematology/Oncology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-07-17
Collections
Oncology
GPX4 inhibitors for cancer therapy
CU20261
Potent, selective GPX4 inhibitors induce ferroptosis to target EMT-driven, drug-resistant cancers and enable GPX4 research.
Tags
Neoplasm
Active site
Allosteric regulation
Inventors
Brent Stockwell
Hengrui Liu
Manager
Joan Martinez
Departments
Biological Sciences
Chemistry
Divisions
Faculty of the Arts & Sciences
Release Date
2025-05-01
Programmable bacteria for targeted delivery of cancer therapeutics
CU18339
Engineered tumor-targeting bacteria deliver immunotherapies locally, boosting efficacy and reducing systemic toxicity in cancer treatment.
Tags
Neoplasm
Antigen
Cancer immunotherapy
Inventors
Candice Gurbatri
Nicholas Arpaia
Sreyan Chowdhury
Manager
Cynthia Lang
Departments
Biomedical Engineering
Microbiology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-04-07
Targeting PAG for cancer immunotherapy
CU23123
PAG-targeting antibodies boost T cell activation, inhibit PD-1 signaling, and reduce tumor growth, enabling monotherapy or combo immunotherapy.
Tags
Neoplasm
Animal disease model
Cancer immunotherapy
Inventors
Adam Mor
Manager
Cynthia Lang
Departments
Rheumatology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-04-07
cGAS inhibitor for robust anti-tumor immunity activation
CU23316
Bioavailable, chemically modified cGAS inhibitors enhance oral bioavailability to boost anti-tumor immunity via the cGAS–STING pathway.
Tags
Neoplasm
Aminopeptidase
Autoimmune disease
Inventors
Benjamin Izar MD, PhD
Donald William Landry MD, Ph.D.
Lindsay Caprio
Manager
Joan Martinez
Departments
Medicine
Program in Cellular, Molecular, Structural and Genetic Studies
Divisions
Columbia University Medical Center (CUMC)
Faculty of the Arts & Sciences
Release Date
2024-09-26
Generation of self-renewed CD4+ T cells for cancer and viral disease immunotherapy
CU24385
Ex vivo culture method yields durable, polyfunctional cytotoxic CD4+ T cells for enhanced cancer and viral immunotherapies.
Tags
Neoplasm
Antigen
Cell culture
Inventors
Mithil Soni
Pawel Muranski
Prabesh Khatiwada
Manager
Jerry Kokoshka
Departments
Columbia Center for Translational Immunology
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-09-16
Combination therapy to increase the efficacy of antibody-drug conjugates in bladder cancer
CU24095
Small molecule reprograms bladder cancer cells to upregulate antigens, boosting antibody-drug conjugate efficacy. 14 words.
Tags
Neoplasm
Antibody-drug conjugate
Antigen
Inventors
John Robert Christin
Michael Shen Ph.D.
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-09
Combinatorial treatment LZTR1 mutant tumors by inhibiting oncogenic substrates
CU23141
Combinatorial inhibitors target LZTR1-mutant cancers by suppressing EGFR, AXL, and RIT1 to reduce tumor growth.
Tags
Neoplasm
Breast cancer
Colorectal cancer
Inventors
Anna Lasorella
Antonio Iavarone
Aram Ko
Manager
Kristin Neuman
Departments
Neurology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-06-06
Combination therapy for the treatment of melanoma
CU16039
Selective NF-kB c-Rel inhibitor plus immune checkpoint blockade boosts therapy for drug-resistant metastatic melanoma.
Tags
Neoplasm
Cancer immunotherapy
Chemotherapy
Inventors
Sankar Ghosh
Yenkel Grinberg-Bleyer
Manager
Cynthia Lang
Departments
Microbiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-05-24
Engineered model of human bone marrow for diagnosis and prediction of cancer metastasis
CU23273
Engineered patient-specific bone marrow model predicts cancer metastasis, metastasis progression, and treatment response non-invasively.
Tags
Neoplasm
Assay
Autoimmune disease
Inventors
Daniel Naveed Tavakol
Gordana Vunjak-Novakovic
Pamela Graney
Manager
Cynthia Lang
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2024-04-08
Collections
Oncology
Platform/Research Tool
Medical Device
Patient-specific organoid system for pancreatic ductal adenocarcinoma (PDAC) drug screening
CU24025
Patient-specific pancreatic cancer organoids with patient immune cells enable high-throughput drug screening and personalized therapy insights.
Tags
Neoplasm
Cell therapy
High-throughput screening
Inventors
Gulam Manji
Ilenia Pellicciotta
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-11-30
Collections
Oncology
Modular, multi-tissue system for in vitro modeling of systemic disease
CU19102
Multi-tissue organ-on-a-chip platform enables vascular-coupled, patient-specific modeling of systemic disease and cancer metastasis.
Tags
Neoplasm
Circulatory system
Crosstalk
Inventors
Alan Chramiec
Andrea Califano Ph.D.
Ece Ozturk
Manager
Cynthia Lang
Departments
Biochemistry & Molecular Biophysics
Biomedical Engineering
Biomedical Informatics
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-10-31
Collections
Oncology
Platform/Research Tool
T cell co-receptor clustering for cancer treatment
CU22398
Bispecific SLAMF6 antibodies compartmentalize T cells to enhance activation, enabling targeted cancer immunotherapy with fewer off-target effects.
Tags
Neoplasm
Cancer immunotherapy
Co-receptor
Inventors
Adam Mor
Manager
Cynthia Lang
Departments
Rheumatology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-09-05
Collections
Oncology
Non-invasive method for detection of cancer methylomes
CU21185
Non-invasive methylation profiling of tumor cfDNA enables early cancer detection, tumor origin, and targeted treatment insights.
Tags
Neoplasm
5-Methylcytosine
Antibody
Inventors
Hui Zhou
Regina Santella Ph.D.
Zhiguo Zhang
Manager
Joan Martinez
Departments
Environmental Health Science
Genetics & Development
Institute for Cancer Genetics
Divisions
Columbia University Medical Center (CUMC)
Mailman School Of Public Health (MSPH)
Release Date
2023-08-04
Collections
Oncology
Targeting the CD58:CD2 axis for cancer immunotherapy
CU21140
Activates CD28-CD8+ T-cells via CD58:CD2 axis, offering an immunotherapy option for PD-1–unresponsive cancers.
Tags
Neoplasm
Antibody
Antigen-presenting cell
Inventors
Benjamin Izar MD, PhD
Johannes Melms
Patricia Ho
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-06-23
Collections
Oncology
Tumor irradiation role in adenosine signaling
CU22323
Examines how tumor irradiation modulates adenosine signaling to enhance immunotherapy and tumor microenvironment targeting.
Tags
Neoplasm
Adenosine
Cancer immunotherapy
Inventors
Catherine Spina MD, PhD
Shruti Bansal
Manager
Joan Martinez
Departments
Radiation Oncology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-06-02
Collections
Oncology
Targeting ID2 to impair hypoxic cancer stem cell proliferation
CU16166
Targeting ID2–DYRK1A/B axis degrades HIF2a in hypoxic cancer stem cells, offering glioblastoma–focused, broad oncologic potential.
Tags
Neoplasm
Angiogenesis
Cancer stem cell
Inventors
Anna Lasorella
Antonio Iavarone
Manager
Kristin Neuman
Departments
Neurology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-19
Collections
Oncology
Small molecule inhibitors of the ID2/VHL interaction
CU17182
Four small molecules block ID2/VHL, promote HIF degradation, potentially slowing tumor growth and angiogenesis in cancers.
Tags
Neoplasm
Angiogenesis
Cell growth
Inventors
Anna Lasorella
Antonio Iavarone
Dan Sherman
Manager
Kristin Neuman
Departments
Institute for Cancer Genetics
Neurology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-19
Collections
Small Molecule
Oncology
Co-delivery platform for enhanced nucleic acid therapeutics
CU21087
Co-delivery platform stabilizes nucleic acid therapeutics with exosome carriers and RISC associations, boosting efficacy while reducing off-targets.
Tags
Neoplasm
Gene expression
Head and neck cancer
Inventors
Akiva Mintz
Fatemeh Momen-Heravi
Manager
Joan Martinez
Departments
College of Dental Medicine
Radiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-19
Collections
Gene Therapy
Oncology
Platform/Research Tool
Computational method for brain tumor classification and improved prognosis
CU21156
Integrates multi-omics to subtype glioblastoma, revealing four functional states and subtype-specific treatment targets.
Tags
Neoplasm
Breast cancer
Glioblastoma
Inventors
Anna Lasorella
Antonio Iavarone
Manager
Kristin Neuman
Departments
Neurology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-01
Collections
Oncology
Recombinant ILT3 protein-produced antibodies for immunotherapy treatment of cancer
CU15207
Engineered anti-ILT3 antibodies enable targeted cancer immunotherapy, modulating myeloid signals and enhancing immune blockade.
Tags
Neoplasm
Acute myeloid leukemia
Allotransplantation
Inventors
George Vlad Ph.D.
Nicole Suciu-Foca
Zheng Xu
Manager
Sara Gusik
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2023-03-08
Collections
Oncology
Programmable nanoencapsulation for probiotic delivery
CU21284
Programmable nanoencapsulated probiotics boost cancer therapy safety and efficacy by tunable, immune-evasive bacterial delivery.
Tags
Neoplasm
Bacteria
Bacterial capsule
Inventors
Jaeseung Hahn
Kam Leong
Tal Danino
Manager
Cynthia Lang
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-01-30
Collections
Oncology
Inhibition of osteoblast activity to treat acute myeloid leukemia (AML) and myelodysplasia (MD)
CU21283
Inhibits osteoblast–AML crosstalk via kynurenine/SAA axis, reducing leukemia progression; therapeutic and biomarker potential.
Tags
Neoplasm
5-HT receptor
Acute myeloid leukemia
Inventors
Marta Galan-Diez
Stavroula Kousteni
Manager
Jerry Kokoshka
Departments
Herbert and Florence Irving Center for Clinical Research
Physiology and Cellular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-01-24
Collections
Oncology
Conditional knockout mouse model for the Phf6 gene
CU22370
A tissue-specific Phf6 conditional knockout mouse model for studying Börjeson-Forssman-Lehmann syndrome and hematologic cancers.
Tags
Neoplasm
Acute myeloid leukemia
Gene
Inventors
Adolfo A. Ferrando M.D., Ph.D.
Teresa Palomero Vasquez
Manager
Joan Martinez
Departments
Institute for Cancer Genetics
Pathology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2022-08-20
Conditional knockout mouse model to study genomic instability of BRCA1 mutations
CU23027
Inducible BRCA1 exon 2 knockout mouse model to study BRCA1-related genomic instability, tumorigenesis, and therapy screening.
Tags
Neoplasm
Ablation
Allele
Inventors
Foon Wu-baer
Richard Baer Ph.D.
Manager
Joan Martinez
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Release Date
2022-10-10
Collections
Oncology
Women's Health
Fusion protein as target for brain cancer therapy
CU12240
Targeting FGFR-TACC gene fusions in glioblastoma with kinase inhibitors; precision therapy and diagnostic tools.
Tags
Neoplasm
Assay
Chemotherapy
Inventors
Anna Lasorella
Antonio Iavarone
Raul Rabadan
Manager
Kristin Neuman
Departments
Biomedical Informatics
Neurology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-09-15
Collections
Small Molecule
Oncology
Tumor-infiltrating lymphocyte and organoid co-culture for patient-specific immunotherapy
CU22128
Ex vivo tumor-lymphocyte co-culture screens patient TILs for tumor killing, guiding pre-treatment immunotherapy choices and cost savings.
Tags
Neoplasm
Cell culture
Cytotoxicity
Inventors
Alana Nguyen
Michael Shen Ph.D.
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-08-22
Collections
Oncology
Platform/Research Tool
Probiotic-guided CAR-T cell system for targeted cancer immunotherapy
CU22211
Engineered probiotic-guided CAR-T therapy targets solid tumors, recruiting immune cells and enhancing immunotherapy with tumor-colonizing bacteria.
Tags
Neoplasm
Autoimmune disease
Cancer immunotherapy
Inventors
Candice Gurbatri
Jongwon Im
Nicholas Arpaia
Manager
Cynthia Lang
Departments
Biomedical Engineering
Microbiology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2022-02-04
Collections
Oncology
Master regulators of regulatory T cell tumor infiltration
CU21189
Target 17 tumor-regulatory T cell master regulators to selectively modulate infiltration, boosting anti-tumor immunity with CRISPR-validated precision.
Tags
Neoplasm
CRISPR
Cancer immunotherapy
Inventors
Aleksandar Obradovic
Andrea Califano
Casey Roy Ager
Manager
Joan Martinez
Departments
Biomedical Informatics
Medicine
Systems Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2021-02-03
Collections
Oncology
Automated 3D modeling of diseased livers using artificial intelligence
CU19417
Automated, AI-guided 3D liver modeling from CT: segmenting heterogeneous diseased tissue for safer interventions.
Tags
Neoplasm
3D modeling
Arthroscopy
Inventors
Binsheng Zhao
Larry Schwartz
Xiaotao Guo
Manager
Joan Martinez
Departments
Radiology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2020-06-12
Collections
Oncology
Digital Health (Software, AI, bioinformatics, etc)
Catheter-based optical method for improving treatment of cardiac arrhythmias
CU17035
A catheter-based optical method ensures accurate heart tissue contact before radiofrequency ablation, improving arrhythmia treatment outcomes.
Tags
Neoplasm
Atrial fibrillation
Cardiac muscle
Inventors
Christine P. Hendon
Mohammad Zaryab
Rajinder Singh-Moon
Manager
Dovina Qu
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2020-02-14
Collections
Cardiovascular
Sorting of extracellular vesicles for precise, cell-specific diagnostics
CU19242
Sorting extracellular vesicles by parent cell type enables precise, non-invasive, multi-organ diagnostics from a single blood sample.
Tags
Neoplasm
Assay
Cardiac muscle
Inventors
Bohao Liu
Bryan Wang
Gordana Vunjak-Novakovic
Manager
Cynthia Lang
Departments
Biomedical Engineering
Program in Cellular, Molecular, Structural and Genetic Studies
Divisions
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2020-01-13
Collections
Platform/Research Tool
Medical Device
Harmonic motion elastography for noninvasive tumor imaging in vivo
CU19055
Noninvasive harmonic motion elastography images tumor stiffness in real time, improving margins, monitoring therapy, and guiding surgery.
Tags
Neoplasm
Breast
Breast cancer
Inventors
Alireza Nabavizadehrafsanjani
Elisa Konofagou
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2019-12-16
Collections
Oncology
Women's Health
Vibrational probes for metabolic imaging in live cells and organisms
CU19023
Vibrational IR probes enable non-destructive, real-time metabolic imaging in live cells and whole organisms at subcellular resolution.
Tags
Neoplasm
Amino acid
Brain
Inventors
Lingyan Shi
Wei Min
Manager
Dovina Qu
Departments
Chemistry
Divisions
Faculty of the Arts & Sciences
Release Date
2019-11-15
Collections
Oncology
Platform/Research Tool
Cardiovascular
Automated medical imaging method for optimized portal venous phase acquisition
CU18342
Automated CNN-based portal venous phase tuning improves tumor vascular density and volume assessment, enabling unbiased treatment response monitoring.
Tags
Neoplasm
Algorithm
Angiogenesis
Inventors
Binsheng Zhao
Jingchen Ma
Larry Schwartz
Manager
Joan Martinez
Departments
Radiology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2019-10-17
Collections
Oncology
Intra-arterial administration of peptide-drug conjugates for tumor-selective drug delivery
CU17144
Intra-arterial, flow-arrest delivery preserves cationic peptide-drug charge, enhancing tumor and brain tumor targeting.
Tags
Neoplasm
Apoptosis
Blood–brain barrier
Inventors
Shailendra Joshi
Manager
Sara Gusik
Departments
Anesthesiology
Release Date
2019-08-21
Characterizing and enhancing the efficacy of therapeutic CD8+ T cells
2856
Assay-driven enhancement and characterization of ex vivo CD8+ T cells to predict and boost therapeutic efficacy across cancers and infections.
Tags
Neoplasm
Assay
Autoimmune disease
Inventors
John Loike
Peter Lee
Ralph Steinman
Manager
Sara Gusik
Departments
Biomedical Informatics
Medicine
Physiology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Hematology
Release Date
2018-08-29
Method for determining antigen-specific CD8+ T cell efficacy
2830
Assay-based method quantifies active CD8+ T cells to predict immunotherapy efficacy across cancers, infections, and autoimmune contexts.
Tags
Neoplasm
Antigen
Assay
Inventors
Arthur Karlin
John Loike
Peter Lee
Manager
Sara Gusik
Departments
Biochemistry & Molecular Biophysics
Biomedical Informatics
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2018-08-27
Cell-penetrating TAT oligomers for drug delivery
CU17314
Cell-penetrating TAT oligomers enable targeted drug delivery across membranes, including blood-brain barriers, for tumors and CNS.
Tags
Neoplasm
Apoptosis
Biopharmaceutical
Inventors
Shailendra Joshi
Manager
Sara Gusik
Departments
Anesthesiology
Release Date
2018-07-16
Collections
Oncology
Cholinergic agonists for treating pancreatic cancer
CU17111
Cholinergic agonists (bethanechol) suppress pancreatic cancer growth and stemness via M3 receptor, improving outcomes in models.
Tags
Neoplasm
Adjuvant
Agonist
Inventors
Chandan Guha
Timothy Wang M.D.
Manager
Jerry Kokoshka
Departments
Medicine
Radiation Oncology
Release Date
2018-02-15
Human hybridoma cell lines that produce functional human monoclonal antibodies
1820
Karyochi-based human hybridomas enable fast, scalable production of fully human monoclonal antibodies for cancer therapy and diagnostics.
Tags
Neoplasm
Antibody
Antigen
Inventors
Gavreel Kalantarov
Ilya Trakht
Manager
Jerry Kokoshka
Departments
Anesthesiology
Herbert and Florence Irving Center for Clinical Research
Divisions
Columbia University Medical Center (CUMC)
Release Date
2017-08-23
Optically-integrated catheter for real-time monitoring of lesion formation during radiofrequency ablation
CU16008
Optically integrated catheter enables real-time, high-resolution monitoring of lesion formation during cardiac radiofrequency ablation.
Tags
Neoplasm
Atrial fibrillation
Cardiac muscle
Inventors
Christine P. Hendon
Rajinder Singh-Moon
Manager
Dovina Qu
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2016-08-26