Unmet Need: Accurate in vivo model for Alzheimer’sdisease that mimics human pathologies. These animal models display basic biochemical alterations similar to those in human Alzheimer’sdisease patients, thus presenting a tool for Alzheimer’sdisease research with more accurate pathologies. These zebrafish lines have been validated in vivo and compared to human Alzheimer’sdisease cohort datasets.
Early detection of cognitive decline in aging and neurodegenerative diseases. This technology is a self-reportable measure of perceived cognitive change that can be used to track cognitive outcomes for treatment trials in neurologic populations. The Technology: A validated and sensitive self-reported scale of subtle cognitive changes.
This technology is an artificial intelligence system for eye disease detection that is trained using eye movements of clinical and medical experts as they view ophthalmic images. Unmet Need: Interpretable clinical AI system for eye disease detection. The Technology: Expert eye-movement-informed artificial intelligence for eye disease detection.