Categories
Biochemistry
View all technologies
Engineered anti-
Cre
antibody
for detection of
Cre
CU23045
Engineered monoclonal anti-Cre antibody enables precise, tissue-specific Cre detection, improving reliability over current reagents.
Tags
Antibody
Cre recombinase
DNA sequencing
Inventors
David Ng
Susan Brenner-Morton
Manager
Jerry Kokoshka
Departments
Biochemistry
Mortimer B. Zuckerman Mind Brain Behavior Institute
Release Date
2022-10-31
Sensitive SARS-CoV-2
antigen
test
CU21002
Ultra-sensitive SARS-CoV-2 antigen sandwich ELISA using dual nucleocapsid antibodies for rapid, low-viral-load detection.
Tags
Antibody
Antigen
Assay
Inventors
David Da-i Ho M.D.
Lihong Liu
Manager
Kristin Neuman
Departments
Medicine
Physicians & Surgeons
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-04-25
CMOS imaging arrays for high-speed
fluorescence
lifetime imaging
CU12003
CMOS-SPAD FLIM array enables 200 fps wide-field imaging with on-chip timing, compact, cost-effective for live-cell and high-throughput assays.
Tags
CMOS
DNA sequencing
Data acquisition
Inventors
Kenneth Shepard
Ryan M. Field
Manager
Greg Maskel
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-10-09
Peptide nucleic acid conjugates for altering
gene
expression
in cancer
CU16241
Selective peptide nucleic acid polymers block cancer gene expression, targeting mutations like BRAFV600E with improved delivery and specificity.
Tags
Bioavailability
Biosensor
Cell culture
Inventors
Gary Schwartz M.D.
Jeffrey Rothman M.D.
Manager
Joan Martinez
Departments
Medicine
Oncology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-11-03
Collections
Gene Therapy
Oncology
Non-invasive laser therapy for
cytokine
modulation and corneal inflammation management
CU18315
Femtosecond laser therapy non-invasively modulates corneal cytokines to reduce inflammation and keratocyte apoptosis, preserving tissue.
Tags
Analgesic
Antibiotic
Apoptosis
Inventors
Sinisa Vukelic
Manager
Dovina Qu
Departments
Mechanical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2024-08-17
Collections
Ophthalmology
NAPA-ID: a proximity-based system to decode
protein
-
protein
interactions
CU26166
NAPA-ID enables antibody-guided, proximity labeling of protein interactions without genetic editing, compatible with standard proteomics workflows.
Tags
Antibody
Biological engineering
Biomarker
Inventors
Jeremy Cartalas
Sara Zaccara
Manager
Jerry Kokoshka
Departments
Systems Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2026-02-17
Mechanobiological
assay
for glaucoma drug screening
CU23377
In vitro mechanobiological assay using patient Schlemm’s canal cells; high-throughput pore formation tests to screen glaucoma drugs.
Tags
Aqueous humour
Assay
Biomechanics
Inventors
Darryl Overby
Joseph van Batenburg-Sherwood
Krishnakumar Kizhatil
Manager
Kristin Neuman
Departments
Biomedical Engineering
Ophthalmology
Divisions
College of Engineering
Columbia University Medical Center (CUMC)
Release Date
2025-01-13
Engineered cell line for inducible
protein
expression
for single-molecule imaging
CU24352
Inducible CHO cell line enables single-molecule GPCR interaction tracking in live cells with high-resolution smFRET.
Tags
Cell membrane
Cell signaling
Cell surface receptor
Inventors
Jonathan Javitch
Wesley Asher
Manager
Jerry Kokoshka
Departments
Psychiatry
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-05
Sensitive, non-invasive diagnostic
assay
for detecting prostate cancer
CU22152
Noninvasive urine RAD9 methylation test detects aggressive prostate cancer, boosting accuracy and enabling point-of-care prognosis.
Tags
Assay
Bladder cancer
Blood test
Inventors
Catherine Spina MD, PhD
Howard Brett Lieberman Ph.D.
Kevin Hopkins
Manager
Kristin Neuman
Departments
Center for Radiological Research
Radiation Oncology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-08-23
Serum Amyloid A1
antibody
to treat leukemias
CU22360
SAA1-targeting antibody blocks bone marrow–driven leukemia progression, aiming to prevent AML/MDS relapse and broaden hematologic cancer treatment.
Tags
Acute lymphoblastic leukemia
Acute myeloid leukemia
Breast cancer
Inventors
Marta Galan-Diez
Stavroula Kousteni
Manager
Jerry Kokoshka
Departments
Herbert and Florence Irving Center for Clinical Research
Physiology and Cellular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-04-10
Assay
for neurotransmitter leakage detection using fluorescent analogues
CU22294
Real-time, non-radioactive fluorescent assay tracks vesicular neurotransmitter leakage in cells for high-throughput neurological research.
Tags
Assay
High-throughput screening
Isotopic labeling
Inventors
Gary Miller
Meghan L. Bucher
Manager
Joan Martinez
Departments
Environmental Health Science
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2023-09-08
Collections
CNS/Neurology
Platform/Research Tool
Protein
fragment to promote neurogenesis
CU13345
Dominant-negative ATF5 fragment drives differentiation of neuroprogenitors into mature neurons and glial cells, enabling brain regeneration research.
Tags
Astrocyte
Cellular differentiation
Central nervous system
Inventors
James M. Angelastro
Lloyd Greene PhD
Manager
Jerry Kokoshka
Departments
Molecular Biosciences
Pathology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-01-13
Broadly neutralizing
antibody
against SARS-CoV-2 variants and related sarbecoviruses
CU24218
Broadly neutralizing antibody targets SARS-CoV-2 variants and related sarbecoviruses, enabling versatile, durable treatment and prophylaxis.
Tags
Antibody
Antiviral drug
Clade
Inventors
David Da-i Ho M.D.
Jian Yu
Lawrence S. Shapiro Ph.D.
Manager
Kristin Neuman
Departments
Aaron Diamond AIDS Research Center (ADARC)
Biochemistry and Molecular Biophysics / Ophthalmology
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-09-16
Monoclonal
antibody
for isolation of LRP1 for treatment of neurodegenerative diseases
CU25221
Monoclonal antibody enables native LRP1 purification across species, boosting neurodegenerative therapy research and production.
Tags
Affinity chromatography
Chromatography
Epitope
Inventors
Gabriele Cerutti
Lawrence S. Shapiro Ph.D.
Susan Brenner-Morton
Manager
Kristin Neuman
Departments
Biochemistry
Biochemistry and Molecular Biophysics / Ophthalmology
Mortimer B. Zuckerman Mind Brain Behavior Institute
Release Date
2025-04-24
Combination therapy to increase the efficacy of
antibody
-drug conjugates in bladder cancer
CU24095
Small molecule reprograms bladder cancer cells to upregulate antigens, boosting antibody-drug conjugate efficacy. 14 words.
Tags
Antibody-drug conjugate
Antigen
Biopharmaceutical
Inventors
John Robert Christin
Michael Shen Ph.D.
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-09
BulkArg: computational pipeline for improving
protein
crystallization propensity
CU23101
A computational pipeline suggesting lysine-to-arginine substitutions to boost crystallization propensity and speed structure determination.
Tags
Arginine
Biological target
Crystallization
Inventors
Blaine L. Loughlin
John F. Hunt
Nooriel E. Banayan
Manager
Ofra Weinberger
Departments
Biological Sciences
Divisions
Faculty of the Arts & Sciences
Release Date
2023-09-13
Clinical management of Interstitial Lung Disease using a multiplex real-time PCR assay to quantify leukocyte telomere length
CU24245
Multiplex real-time PCR quantifies average leukocyte telomere length to guide ILD treatment decisions and outcomes.
Tags
Assay
Biomarker
Immunosuppression
Inventors
Chad Newton
Christine K. Garcia
David Zhang
Manager
Kristin Neuman
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-01-13
Antibody
therapeutic targeting Funsobacterium nucleatum-mediated diseases
CU21261
Monoclonal antibody against Annexin A1 blocks Fusobacterium nucleatum invasion, offering targeted prevention and treatment of Fn-related cancers.
Tags
Antibiotic
Antibody
Bacteria
Inventors
Yiping Han
Manager
Jerry Kokoshka
Departments
Periodontics
Divisions
Columbia University Medical Campus (CUMC)
Release Date
2024-02-09
Collections
Rare Disease
Oncology
Antibody
-like molecule for specific and potent HIV latency reversal
CU23253
Bispecific antibody targets CD4+ T cells and IL-15 receptor to deliver potent latency reversal agents, reactivating HIV reservoirs.
Tags
Antiviral drug
CD4
Combination therapy
Inventors
David Da-i Ho M.D.
Hiroshi Mohri
Jian Yu
Manager
Kristin Neuman
Departments
Aaron Diamond AIDS Research Center (ADARC)
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-10-25
Collections
Immunology & Inflammation
A spinal motor neuron-specific enhancer for cell-type specific gene expression control in the developing and adult central nervous system
CU22281
Spinal motor neuron–specific enhancer enables AAV-deliverable, cell-type–restricted gene overexpression/knockdown in adults and development.
Tags
Central nervous system
Cholinergic
Gene expression
Inventors
Hynek Wichterle
Tulsi Patel
Manager
Jerry Kokoshka
Departments
Center for Neurobiology & Behavior
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-02
Collections
Gene Therapy
CNS/Neurology
Extracellular vesicle-based
assay
for detecting head and neck cancer
CU21332
Noninvasive chip assay detects tumor-enriched proteins on patient extracellular vesicles to screen and monitor head-and-neck cancer.
Tags
Assay
Body fluid
Cancer staging
Inventors
Akiva Mintz
Fatemeh Momen-Heravi
Gordana Vunjak-Novakovic
Manager
Joan Martinez
Departments
Biomedical Engineering
College of Dental Medicine
Radiology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-06-28
Collections
Oncology
Inhibitory peptides targeting SARS-CoV-2 envelope
protein
CU21015
Inhibitory peptides block SARS-CoV-2 envelope protein, aiming for broad coronavirus protection by disrupting viral assembly and replication.
Tags
Combination therapy
Gene therapy
Protein
Inventors
Kazushige Yoshida
Masayuki Yazawa Ph.D.
Ramsey Bekdash
Manager
Kristin Neuman
Departments
Rehabilitation & Regenerative Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-10-03
Chaperone-enhanced platform for rescuing
protein
misfolding in neurodegenerative diseases
CU22082
Chaperone-based gene therapy stabilizes RNA-binding proteins, reducing misfolding and aggregation in ALS/FTD. 120-150 chars.
Tags
Amyotrophic lateral sclerosis
Biomarker
Chaperone (protein)
Inventors
Alejandro Chavez
Samuel J. Resnick
Manager
Cynthia Lang
Departments
Pathology & Cell Biology
Program in Cellular, Molecular, Structural and Genetic Studies
Divisions
Columbia University Medical Center (CUMC)
Faculty of the Arts & Sciences
Release Date
2025-07-17
Plasma-based, biopsy-free cancer detection
assay
CU23111
Plasma-based, blood biopsy-free cancer detection using deep learning on cfDNA methylation to diagnose multiple cancers non-invasively.
Tags
Assay
Cancer
DNA methylation
Inventors
Xu Hua
Zhiguo Zhang Ph.D.
Manager
Joan Martinez
Departments
Genetics & Development
Institute for Cancer Genetics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-03-03
Collections
Oncology
Bacterial strain for improved
protein
production
CU15280
Engineered BL21(DE3) E. coli strain boosts protein yield, enabling reliable production of unstable proteins for faster biotech development.
Tags
Cell culture
Escherichia coli
Gene expression
Inventors
Maxwell E. Gottesman
Manager
Joan Martinez
Departments
Biochemistry & Molecular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-11-17
Computational tool to predict RNA binding
protein
targets for
gene
therapy and agricultural bioengineering
CU23342
PPRDecoder: a genome-wide, unbiased algorithm predicting RNA targets of PPR proteins, accelerating gene regulation research.
Tags
Algorithm
Biological engineering
Biotechnology
Inventors
Chaolin Zhang PhD
Manager
Joan Martinez
Departments
Biochemistry & Molecular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-08-04
Collections
Gene Therapy
Recombinant ILT3
protein
-produced antibodies for immunotherapy treatment of cancer
CU15207
Engineered anti-ILT3 antibodies enable targeted cancer immunotherapy, modulating myeloid signals and enhancing immune blockade.
Tags
Acute myeloid leukemia
Allotransplantation
Antibody
Inventors
George Vlad Ph.D.
Nicole Suciu-Foca
Zheng Xu
Manager
Sara Gusik
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2023-03-08
Collections
Oncology
D1-
Cre
knock-in mouse for genetic targeting of basal ganglia circuits
CU26035
CRISPR knock-in D1-Cre mouse ensures precise, endogenous D1 neuron targeting in basal ganglia for targeted circuit studies.
Tags
Basal ganglia
Cre recombinase
Dopamine
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-13
Chimeric
protein
for directly modulating calcium ion channel activity
CU23388
Genetically encoded enhancer boosts L-type Ca2+ currents with tissue targeting, rescuing dysfunctional calcium channels.
Tags
Actuator
Antiarrhythmic agent
Arrhythmia
Inventors
Manu Ben-Johny
Pedro Javier del Rivero Morfin
Manager
Kristin Neuman
Departments
Physiology and Cellular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-05
Collections
Cardiovascular
Recombinant
protein
to treat inflammation
CU23248
Recombinant FSTL-1 protein targets and reduces cardiac inflammation, aiding Kawasaki disease research and myocarditis treatment.
Tags
Anti-inflammatory
Atherosclerosis
Biomarker
Inventors
Mark Gorelik
Manager
Sara Gusik
Departments
Pediatrics/Rheumatology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-10
Collections
Cardiovascular
Protein
sequencing with a cavity-separated multi-nanopore device
CU22073
Cavity-separated multi-nanopore sequencing enables high-throughput, library-free, single-molecule protein sequencing with improved accuracy.
Tags
Drug development
Gene expression
Ion
Inventors
Jakob Buchheim
Kenneth Shepard
Manager
Greg Maskel
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-01-31
Anxa1-
Cre
mouse for selective modeling of dopaminergic neurons in Parkinson's disease
CU26032
Anxa1-Cre mouse enables precise manipulation of a vulnerable dopaminergic neuron subtype to study early Parkinson’s motor deficits.
Tags
Biomarker
Causality
Cre recombinase
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-07
A mouse model expressing
recombinase
in dopamine transporter-positive neurons
CU26033
Precise FlpO recombination in dopamine transporter neurons via CRISPR knock-in, enabling targeted dopaminergic research.
Tags
Basal ganglia
Dopamine
Dopamine transporter
Inventors
Rui Costa
Manager
Kristin Neuman
Departments
Neuroscience
Divisions
Zuckerman Mind Brain Behavior Inst
Release Date
2025-11-07
High-throughput single-cell multi-omics platform for integrated RNA, DNA, and
protein
analysis
CU21072
Integrated single-cell platform enabling high-throughput RNA, DNA, and protein profiling for holistic cellular insights and scalable studies.
Tags
Biomarker
Cell nucleus
Drug discovery
Inventors
Peter A. Sims
Timothy R. Olsen
Manager
Cynthia Lang
Departments
Biochemistry & Molecular Biophysics
Systems Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-01-02
Collections
Genomics & Multi-Omics
Fusion
protein
as target for brain cancer therapy
CU12240
Targeting FGFR-TACC gene fusions in glioblastoma with kinase inhibitors; precision therapy and diagnostic tools.
Tags
Assay
Chemotherapy
Glioblastoma
Inventors
Anna Lasorella
Antonio Iavarone
Raul Rabadan
Manager
Kristin Neuman
Departments
Biomedical Informatics
Neurology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-09-15
Collections
Small Molecule
Oncology
Conditional 5-HT1A receptor knockout mouse model for studying antidepressant response
CU25138
Inducible, cell-type specific 5HT1AR knockout mouse model reveals dentate gyrus roles in antidepressant response and mood regulation.
Tags
5-HT receptor
5-HT1A receptor
Antidepressant
Inventors
Rene Hen
Manager
Kristin Neuman
Departments
Pharmacology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-02-28
Human ALFY knock-in mice for studying neurodegenerative disease
CU26143
Human ALFY knock-in mice enable tissue-specific, controllable hALFY expression to study neurodegenerative protein aggregation.
Tags
Autophagy
Copy number variation
Cre recombinase
Inventors
Ai Yamamoto
Manager
Kristin Neuman
Departments
Physiology and Cellular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2026-01-08
Collections
CNS/Neurology
Gene
therapy for metabolic dysfunction-associated steatohepatitis (MASH)
CU25230
Gene therapy restoring retromer activity to treat MASH by normalizing lipid metabolism and reducing fibrosis risk.
Tags
Cirrhosis
Drug discovery
Fibrosis
Inventors
Gregory A. Petsko
Scott A. Small M.D.
Manager
Jerry Kokoshka
Departments
Ann Romney Center for Neurologic Diseases
Neurology
Divisions
Columbia University Medical Center (CUMC)
Harvard Medical School and Brigham & Women’s Hospital
Release Date
2025-07-31
Adeno-associated virus Glut1
gene
therapy for rescuing glucose transport in Glut1 deficiency syndrome
CU15054
AAV-based Glut1 gene therapy restores brain glucose transport in Glut1 deficiency, offering a one-time, long-term treatment.
Tags
Adeno-associated virus
Blood–brain barrier
Cognitive deficit
Inventors
Darryl C. De Vivo
Guangping Gao
Kristin Engelstad
Manager
Kristin Neuman
Departments
Neurology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Office of Technology Management
Release Date
2025-08-19
Aldh3a1-Creert mouse line
CU25020
Inducible Aldh3a1-CreERT mouse enables tamoxifen-controlled lineage tracing of Aldh3a1-positive pancreatic β-cells for diabetes research.
Tags
Aldehyde
Aldehyde dehydrogenase
Beta cell
Inventors
Domenico Accili M.D.
Jinsook Son PhD
Manager
Cynthia Lang
Departments
Endocrinology
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-09-26
Serochip for the diagnosis of tick-borne diseases
CU19325
A programmable peptide microarray enables rapid, high-throughput, single-step serologic diagnosis of multiple tick-borne diseases.
Tags
Antibody
Assay
Epidemiology
Inventors
Adrian Caciula
Nischay Mishra
Rafal Tokarz
Manager
Kristin Neuman
Departments
Center for Infection and Immunity
Epidemiology
Divisions
Mailman School Of Public Health (MSPH)
Release Date
2025-09-04
Chemical painting for high-throughput single-cell drug response analysis
CU23332
Multiplexed infrared imaging enables high-throughput, single-cell drug profiling with ML-enabled mechanism-of-action predictions.
Tags
Combination therapy
DNA sequencing
Drug discovery
Inventors
Wei Min
Xinwen Liu
Manager
Dovina Qu
Departments
Chemistry
Divisions
Faculty of the Arts & Sciences
Release Date
2025-10-16
Gene
silencing for the treatment of metabolic dysfunction-associated steatohepatitis (MASH)
CU23021
Silencing CASP8-METRN halts progression from steatosis to MASH, offering non-invasive therapy and diagnostic biomarkers.
Tags
Biomarker
Blood plasma
Caspase 8
Inventors
Danish Saleheen
Ira Tabas MD, PhD
Shareef Khalid
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-11-08
Gene
editing for treatment of retinitis pigmentosa
CU23293
CRISPR-based retinal metabolism reprogramming targets PHD2 to slow retinitis pigmentosa progression, offering broad RP treatment potential.
Tags
Adeno-associated virus
CRISPR
CRISPR gene editing
Inventors
Stephen H. Tsang M.D., Ph.D.
Manager
Kristin Neuman
Departments
Ophthalmology
Divisions
College of Physicians and Surgeons (CUMC
Release Date
2024-11-26
Collections
Ophthalmology
Functional tagging of neurons for further integrative analysis
CU24343
In vivo activity-tagging of activated neurons enables high-throughput collection for downstream transcriptomic analysis and function-genome mapping.
Tags
Transcriptome
Inventors
Attila Losonczy
Boaz Nutkovich
Dahlia Kushinsky
Manager
Kristin Neuman
Departments
Brain Sciences
Neuroscience
Divisions
Columbia University Medical Center (CUMC)
Zuckerman Mind Brain Behavior Inst
Release Date
2025-12-01
Conditional knockout mouse model for studying autosomal-dominant optic atrophy
CU26140
A mammalian, cell-type–specific conditional Ssbp1 R107Q mouse model to dissect autosomal-dominant optic atrophy mechanisms.
Tags
Allele
Arginine
Cre recombinase
Inventors
Chyuan-Sheng (Victor) Lin
Nan-Kai Wang
Yunju Tseng
Manager
Kristin Neuman
Departments
Ophthalmology
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2026-01-08
ARP-154 (HeLa T4+) human cancer cell line generated by
gene
transfer for AIDS research
CU24290
CD4-expressing HeLa-derived cell line enables AIDS research; facilitates HIV binding studies, drug screening, and therapeutic development.
Tags
AIDS
Antigen
Autoimmune disease
Inventors
Paul J. Maddon
Richard Axel M.D.
Manager
Joan Martinez
Departments
Biochemistry & Molecular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-05-29
Conditional mouse model for the BARD1
gene
CU23026
A conditional Bard1 mouse model enables tissue-specific gene knockout to study BRCA1/BARD1 cancer risk and therapy.
Tags
Allele
BRCA1
Breast cancer
Inventors
Foon Wu-baer
Richard Baer Ph.D.
Manager
Joan Martinez
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Release Date
2022-10-10
Collections
Oncology
Women's Health
VPS35 floxed mouse model for Alzheimer's drug discovery
CU25395
Inducible, tissue-specific VPS35 knockout mouse enabling controlled adult-onset retromer disruption for Alzheimer’s research.
Tags
Biomarker
Cerebrospinal fluid
Drug discovery
Inventors
Scott A. Small M.D.
Manager
Jerry Kokoshka
Departments
Neurology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-07-31
Live yeast biosensors for pathogen detection
CU21127
Engineered live yeast biosensors emit color/fluorescent signals for rapid, sensitive pathogen detection, including fungi, viruses, and variants.
Tags
Antifungal
Antiviral drug
Assay
Inventors
Virginia W. Cornish
Manager
Joan Martinez
Departments
Chemistry
Divisions
Faculty of the Arts & Sciences
Release Date
2025-03-07
