Tags
Gene expression
View all technologies
Peptide nucleic acid conjugates for altering
gene
expression
in cancer
CU16241
Selective peptide nucleic acid polymers block cancer gene expression, targeting mutations like BRAFV600E with improved delivery and specificity.
Tags
Gene expression
Bioavailability
Biosensor
Inventors
Gary Schwartz M.D.
Jeffrey Rothman M.D.
Manager
Joan Martinez
Departments
Medicine
Oncology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-11-03
Collections
Gene Therapy
Oncology
A spinal motor neuron-specific enhancer for cell-type specific gene expression control in the developing and adult central nervous system
CU22281
Spinal motor neuron–specific enhancer enables AAV-deliverable, cell-type–restricted gene overexpression/knockdown in adults and development.
Tags
Gene expression
Central nervous system
Cholinergic
Inventors
Hynek Wichterle
Tulsi Patel
Manager
Jerry Kokoshka
Departments
Center for Neurobiology & Behavior
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-02
Collections
Gene Therapy
CNS/Neurology
Humanoid-robot capable of facial co-
expression
CU24301
A soft-skinned humanoid robot predicts and synchronizes facial expressions in real time, enhancing natural human-robot interaction.
Tags
Gene expression
Animatronics
Anthropomorphism
Inventors
Hod Lipson
Yuhang Hu
Manager
Dovina Qu
Departments
Mechanical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-02-03
Engineered cell line for inducible protein
expression
for single-molecule imaging
CU24352
Inducible CHO cell line enables single-molecule GPCR interaction tracking in live cells with high-resolution smFRET.
Tags
Gene expression
Cell membrane
Cell signaling
Inventors
Jonathan Javitch
Wesley Asher
Manager
Jerry Kokoshka
Departments
Psychiatry
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-05
Targeted
gene
therapy for retinopathies
CU21122
CRB1-targeted gene therapy delivers isoform-specific CRB1 to Müller glia and photoreceptors, treating CRB1-retinopathies.
Tags
Gene expression
Gene therapy
Genetic disorder
Inventors
Peter M.J. Quinn
Stephen H. Tsang M.D., Ph.D.
Manager
Kristin Neuman
Departments
Ophthalmology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Release Date
2023-07-06
Collections
Ophthalmology
Gene Therapy
ARP-154 (HeLa T4+) human cancer cell line generated by
gene
transfer for AIDS research
CU24290
CD4-expressing HeLa-derived cell line enables AIDS research; facilitates HIV binding studies, drug screening, and therapeutic development.
Tags
Gene expression
AIDS
Antigen
Inventors
Paul J. Maddon
Richard Axel M.D.
Manager
Joan Martinez
Departments
Biochemistry & Molecular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-05-29
Novel prognostic marker for survival in myeloid malignancies
CU18296
Multi-gene transcriptomic classifier using TED markers to predict MDS progression to AML, enabling earlier, accurate prognosis.
Tags
Gene expression
Acute myeloid leukemia
Assay
Inventors
Abdullah Ali Ph.D.
Azra Raza M.D.
Etienne De Clara
Manager
Joan Martinez
Departments
Herbert Irving Comprehensive Cancer Center
Medical Oncology
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-05-28
Computational tool to predict RNA binding protein targets for
gene
therapy and agricultural bioengineering
CU23342
PPRDecoder: a genome-wide, unbiased algorithm predicting RNA targets of PPR proteins, accelerating gene regulation research.
Tags
Gene expression
Algorithm
Biological engineering
Inventors
Chaolin Zhang PhD
Manager
Joan Martinez
Departments
Biochemistry & Molecular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-08-04
Collections
Gene Therapy
Gene
editing to treat retinal dystrophies
CU22019
Prime editing corrects CRB1 mutations in retinal dystrophy, offering isoform-independent gene therapy and research tool potential.
Tags
Gene expression
Cell therapy
Gene therapy
Inventors
Bruna Lopes da Costa
Peter M.J. Quinn
Stephen H. Tsang M.D., Ph.D.
Manager
Kristin Neuman
Departments
Biomedical Engineering
Ophthalmology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2022-10-31
Collections
Ophthalmology
Gene Therapy
Transcriptional reprogramming platform for neuroprotection, rejuvenation, and treatment of motor neuron diseases
CU23208
AAV-delivered Islet1/Lhx3 re-expression reprograms motor neurons, restoring youthful resilience to prevent motor neuron degeneration.
Tags
Gene expression
Amyotrophic lateral sclerosis
Gene therapy
Inventors
Emily Rhodes Lowry
Hynek Wichterle
Tulsi Patel
Manager
Jerry Kokoshka
Departments
Center for Neurobiology & Behavior
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-01-18
Collections
Gene Therapy
Conditional mouse model for the BARD1
gene
CU23026
A conditional Bard1 mouse model enables tissue-specific gene knockout to study BRCA1/BARD1 cancer risk and therapy.
Tags
Gene expression
Allele
BRCA1
Inventors
Foon Wu-baer
Richard Baer Ph.D.
Manager
Joan Martinez
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Release Date
2022-10-10
Collections
Oncology
Women's Health
Truncated ATF5, CEBPB, and CEBPD inhibitors for effective cancer treatment
CU21274
Short cell-penetrating truncated inhibitors target ATF5/CEBPB/CEBPD, suppressing cancer survival across tumor types.
Tags
Gene expression
Breast cancer
Cancer
Inventors
James M. Angelastro
Lloyd Greene PhD
Qing Zhou
Manager
Jerry Kokoshka
Departments
Molecular Biosciences
Pathology
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-10-31
Collections
Oncology
Lung organoid cells for therapeutic intervention
CU23361
Therapeutic lung regeneration via patient-specific stem cell–derived distal lung organoids with graftable basal and secretory cells.
Tags
Gene expression
Cell therapy
Chronic obstructive pulmonary disease
Inventors
Hans-Willem Snoeck
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-09-08
Genomic stabilization therapy for enhanced in vitro human embryo fertilization and survival
CU18389
Synthetic mRNA–based genome stabilization enhances human embryo viability in IVF, aiming higher success, reduced mosaicism, and lower costs.
Tags
Gene expression
Aneuploidy
Assay
Inventors
Dietrich Egli
Manager
Kristin Neuman
Departments
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-08-24
Collections
Women's Health
CRISPR-based system for detecting DNA transfer and recording biological signals
CU20160
CRISPR-based platform detects exogenous DNA transfer and records temporal biological signals in engineered cells for rapid screening.
Tags
Gene expression
Bioinformatics
CRISPR
Inventors
Harris Wang
Sung Sun Yim
Manager
Cynthia Lang
Departments
Systems Biology
Release Date
2023-12-06
Collections
Platform/Research Tool
Host proteases necessary for human parainfluenza virus spread in human lung
CU22326
Identifies HPIV spread proteases; shows serine protease inhibitors (nafamostat) hinder lung infection, offering targeted antiviral strategy.
Tags
Gene expression
Antiviral drug
Enzyme inhibitor
Inventors
Anne Moscona
Kyle Stearns
Matteo Porotto
Manager
Kristin Neuman
Departments
Anesthesiology
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-02-15
Bacterial strain for improved protein production
CU15280
Engineered BL21(DE3) E. coli strain boosts protein yield, enabling reliable production of unstable proteins for faster biotech development.
Tags
Gene expression
Cell culture
Escherichia coli
Inventors
Maxwell E. Gottesman
Manager
Joan Martinez
Departments
Biochemistry & Molecular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-11-17
Targeted delivery of anti-microRNA for the treatment of liver fibrosis
CU21066
Liver-targeted exosomes deliver anti-miR-132 to curb fibrosis, reducing collagen and pro-fibrotic signals with tissue specificity.
Tags
Gene expression
Cell membrane
Collagen
Inventors
Akiva Mintz
Fatemeh Momen-Heravi
Manager
Joan Martinez
Departments
College of Dental Medicine
Radiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-02
ATP7B knockout mouse model for Wilson disease
CU18413
ATP7B knockout mouse models Wilson disease, enabling in vivo study of copper accumulation, liver cirrhosis-like pathology, and therapy screening.
Tags
Gene expression
Copper
Drug development
Inventors
Dominik Huster
Olesia Buiakova
Svetlana Lutsenko
Manager
Sara Gusik
Departments
Department of Human Genetics
Divisions
Molecular and Medical Genetics
Release Date
2023-06-28
Collections
Rare Disease
Selective serotonin reuptake inhibitors (SSRIs) for treatment of COPD
CU21249
SSRI-based MMP-1 inhibition slows COPD progression; oral/inhaled delivery reduces cigarette-smoke–driven lung damage and inflammation.
Tags
Gene expression
Bronchodilator
Chronic obstructive pulmonary disease
Inventors
Jeanine D'Armiento
Manager
Jerry Kokoshka
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-07-14
Collections
Small Molecule
Preclinical models of angioimmunoblastic T-cell lymphoma for therapeutic investigation
CU23322
RhoA G17V-driven mouse model of angioimmunoblastic T-cell lymphoma enables translational drug screening and pathogenesis study.
Tags
Gene expression
Cancer cell
Chemotherapy
Inventors
Adolfo A. Ferrando M.D., Ph.D.
Teresa Palomero Vasquez
Manager
Joan Martinez
Departments
Institute for Cancer Genetics
Pathology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2023-06-15
Collections
Oncology
Co-delivery platform for enhanced nucleic acid therapeutics
CU21087
Co-delivery platform stabilizes nucleic acid therapeutics with exosome carriers and RISC associations, boosting efficacy while reducing off-targets.
Tags
Gene expression
Head and neck cancer
Liver
Inventors
Akiva Mintz
Fatemeh Momen-Heravi
Manager
Joan Martinez
Departments
College of Dental Medicine
Radiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-19
Collections
Gene Therapy
Oncology
Platform/Research Tool
Mouse model for ion channel disruption via TRIP8b disruption
CU23232
Inducible mouse model to disrupt TRIP8b, altering HCN ion channel localization in heart/brain cells for in vivo study and drug screening.
Tags
Gene expression
Dendrite
Exon
Inventors
Bina Santoro
Steven A. Siegelbaum PhD
Manager
Jerry Kokoshka
Departments
CENTER OF NEUROBIOLOGY AND BEHAVIOR
Pharmacology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-05-02
Collections
CNS/Neurology
Platform/Research Tool
Cardiovascular
Engineered anti-Cre antibody for detection of Cre
CU23045
Engineered monoclonal anti-Cre antibody enables precise, tissue-specific Cre detection, improving reliability over current reagents.
Tags
Gene expression
Antibody
Cre recombinase
Inventors
David Ng
Susan Brenner-Morton
Manager
Jerry Kokoshka
Departments
Biochemistry
Mortimer B. Zuckerman Mind Brain Behavior Institute
Release Date
2022-10-31
Mouse model for studying immune system lineages
CU23013
T-bet (Tbx21) floxed mouse model enables tissue-specific T cell knockout to study immune lineages and diseases.
Tags
Gene expression
Allele
Arthritis
Inventors
Nezih Cereb
Soo Young Yang
Steven Reiner
Manager
Kristin Neuman
Departments
Microbiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-10-14
Recombinant ILT3 protein-produced antibodies for immunotherapy treatment of cancer
CU15207
Engineered anti-ILT3 antibodies enable targeted cancer immunotherapy, modulating myeloid signals and enhancing immune blockade.
Tags
Gene expression
Acute myeloid leukemia
Allotransplantation
Inventors
George Vlad Ph.D.
Nicole Suciu-Foca
Zheng Xu
Manager
Sara Gusik
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2023-03-08
Collections
Oncology
Peptide targeting CD33 to treat cognitive decline in Alzheimer's Disease patients
CU21001
A cost-effective peptide disrupts CD33-CD45, activates microglia, reduces amyloid, potentially slowing cognitive decline in Alzheimer's.
Tags
Gene expression
Acetylcholinesterase
Acute myeloid leukemia
Inventors
Elizabeth M. Bradshaw
Wassim Elyaman
Manager
Joan Martinez
Departments
Neurology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-02-02
Collections
CNS/Neurology
Protein sequencing with a cavity-separated multi-nanopore device
CU22073
Cavity-separated multi-nanopore sequencing enables high-throughput, library-free, single-molecule protein sequencing with improved accuracy.
Tags
Gene expression
Drug development
Ion
Inventors
Jakob Buchheim
Kenneth Shepard
Manager
Greg Maskel
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-01-31
Conditional knockout mouse model to study genomic instability of BRCA1 mutations
CU23027
Inducible BRCA1 exon 2 knockout mouse model to study BRCA1-related genomic instability, tumorigenesis, and therapy screening.
Tags
Gene expression
Ablation
Allele
Inventors
Foon Wu-baer
Richard Baer Ph.D.
Manager
Joan Martinez
Departments
Pathology
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Release Date
2022-10-10
Collections
Oncology
Women's Health
Method for disease phenotype prediction from genetic mutation
CU21310
Phenotype dosage sensitivity: predicts disease phenotypes from LGD mutations via NMD, enabling personalized ASD outcomes and targeted therapeutics.
Tags
Gene expression
Autism spectrum
Exon
Inventors
Andrew Chiang
Dennis Vitkup
Jiayao Wang
Manager
Joan Martinez
Departments
Biomedical Informatics
Systems Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-09-11
Collections
CNS/Neurology
Platform/Research Tool
High Resolution 3D Imaging of Purkinje Neurons
CU22200
High-resolution 3D Purkinje neuron reconstruction across cerebellar layers using dual immunofluorescence, enabling single-cell visualization.
Tags
Gene expression
3D reconstruction
Antibody
Inventors
Alexei Chemiakine
Salvatore Botta
Vincenzo Alessandro Gennarino
Manager
Jerry Kokoshka
Departments
Genetics & Development
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-08-05
Collections
CNS/Neurology
Inducible mouse line for cardiac NOX2 inhibition
CU22219
Inducible cardiac NRROS-based NOX2 inhibition in mice; tissue-specific ROS control to protect against diet-induced arrhythmias.
Tags
Gene expression
Antioxidant
Atherosclerosis
Inventors
John Morrow
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-02-16
Collections
Cardiovascular
Regulation of cholesterol efflux for treating macular degeneration
CU21299
Promotes retinal cholesterol efflux via CES1 upregulation or EGFR signaling modulation to slow or prevent macular degeneration.
Tags
Gene expression
Cholesterol
Enzyme
Inventors
Stephen H. Tsang M.D., Ph.D.
Yi-Ting Tsai
Manager
Kristin Neuman
Departments
Biomedical Engineering
Ophthalmology
Divisions
College of Physicians and Surgeons (CUMC
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2021-04-27
Collections
Ophthalmology
Gene Therapy
Cross-bred mouse lines for biomedical research
CU21129
Cross-bred, Cre-driver mouse cancer models enable conditional gene activation for efficient, cost-saving tumor research and drug testing.
Tags
Gene expression
BRCA1
Carcinogenesis
Inventors
Cory Abate-Shen Ph.D.
Manager
Joan Martinez
Departments
Urology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2021-01-29
Collections
Oncology
High-throughput in vivo mRNA-based proteomics via next-generation sequencing
CU20206
In vivo mRNA display enables high-throughput, sequencing-based proteomics in cells, linking proteins to mRNA with UMIs.
Tags
Gene expression
Antigen
Assay
Inventors
Panagiotis Oikonomou
Saeed Tavazoie
Manager
Joan Martinez
Departments
Biochemistry
Systems Biology
Divisions
Columbia University Medical Center
Columbia University Medical Center (CUMC)
Release Date
2021-01-29
Collections
Platform/Research Tool
Noninvasive near-infrared brain imaging system
CU19286
ToFF-DOT: wearable, noninvasive near-infrared brain imaging achieving single-cell resolution of neural activity for mapping and research.
Tags
Gene expression
Action potential
Brain mapping
Inventors
Kenneth Shepard
Kevin Renehan
Sajjad Moazeni
Manager
Greg Maskel
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2021-01-15
Collections
CNS/Neurology
Medical Device
Patient-derived organoids to study and treat oral cancer
CU20232
Patient-derived 3D oral cancer organoids enable personalized disease modeling, drug screening, and in vivo xenograft validation.
Tags
Gene expression
Biopsy
Carcinoma
Inventors
Anil K. Rustgi M.D.
Hiroshi Nakagawa
Manager
Joan Martinez
Departments
Herbert Irving Comprehensive Cancer Center
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2020-10-15
Collections
Oncology
Whole methylome sequencing at the single molecule level
CU16353
Single-molecule, targeted methylome sequencing detects methylation types with high sensitivity, enabling precise epigenetic profiling and diagnostics.
Tags
Gene expression
Chemistry
DNA methylation
Inventors
James J. Russo
Jingyue Ju
Steffen Jockusch
Manager
Cynthia Lang
Departments
Chemical Engineering/Applied Chemistry
Chemistry
Genetics & Development
Divisions
Columbia University Medical Center (CUMC)
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and
Release Date
2020-12-24
Mouse line for inducible tissue specific
expression
of peroxisome proliferator-activated receptor gamma
CU20098
Inducible, tissue-specific PPARG expression mouse model with Cre; cross-compatible with any Cre line for diverse disease studies.
Tags
Gene expression
Fluorescence microscope
Gamma ray
Inventors
Cathy L. Mendelsohn
Chyuan-Sheng (Victor) Lin
Tiffany Tate
Manager
Joan Martinez
Departments
Opthamology
Urology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2020-02-14
Collections
CNS/Neurology
Inhibiting chemokine interactions to improve treatment outcomes for prostate cancer
CU19210
Blocking IL-8 and receptors to reduce immunosuppressive tumor infiltration, boosting prostate cancer treatment efficacy.
Tags
Gene expression
Chemokine
Chemotherapy
Inventors
Charles G. Drake
Zoila Areli Lopez-Bujanda
Manager
Joan Martinez
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2020-10-02
Collections
Oncology
RNA regulation of the SLC2A1
gene
for treatment of Glut1 deficiency
CU17177
RNA-based therapy using antisense long non-coding RNA to modulate SLC2A1/Glut1 expression for Glut1 deficiency treatment.
Tags
Gene expression
Anticonvulsant
Biomarker
Inventors
Maoxue Tang
Umrao R. Monani Ph.D.
Manager
Kristin Neuman
Departments
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2019-05-20
Collections
Rare Disease
Ophthalmology
Gene Therapy
Peptide therapy for alcohol abuse disorder
CU16253
Spexin peptide treats alcohol use disorder by reducing craving, offering a novel pathway alongside existing therapies.
Tags
Gene expression
Adipocyte
Disulfiram
Inventors
Jose Leonardo Walewski
Paul Berk M.D.
Manager
Cynthia Lang
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2019-07-22
Modified cell-penetrating ATF5 protein to inhibit cancer cell growth
CU18385
Modified ATF5 peptide blocks cancer survival proteins (CEBPB/CEBPD/CCDC6), inducing cancer cell death; potential targeted therapy.
Tags
Gene expression
Breast cancer
Cancer
Inventors
James M. Angelastro
Lloyd Greene PhD
Xiaotian Sun
Manager
Jerry Kokoshka
Departments
Molecular Biosciences
Pathology
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2019-08-02
Collections
Oncology
Prevention and modulation of chemotherapy resistance in glioblastomas
CU18203
MGMT enhancer targeting with BETi/HATi restores temozolomide sensitivity in glioblastoma, delaying resistance and improving GBM treatment.
Tags
Gene expression
CRISPR
Cell growth
Inventors
Haiyun Gan
Jann Sarkaria
Xiaoyue Chen
Manager
Joan Martinez
Departments
Genetics & Development
Institute for Cancer Genetics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2019-08-01
Collections
Oncology
Imaging tool for early detection of chronic obstructive pulmonary diseases
CU17292
Radiolabeled MMP-targeting probe enables CT-based, early COPD detection and monitoring, leveraging existing imaging and noninvasive strategy.
Tags
Gene expression
Biomarker
CT scan
Inventors
Jeanine D'Armiento
Lynne Johnson
Monica Goldklang
Manager
Jerry Kokoshka
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2019-08-01
Method for improving genomic stability and cell line reprogramming
CU20029
Promotes homologous recombination during reprogramming to boost iPSC genomic stability and reprogramming efficiency.
Tags
Gene expression
DNA replication
Genome
Inventors
Daniela Georgieva
Dietrich (Dieter) Egli
Manager
Kristin Neuman
Departments
Medicine
Pediatrics
Divisions
Columbia University Medical Center (CUMC)
Naomi Berrie Diabetes Center
Release Date
2019-07-22
Delta-2 tubulin for detection and treatment of peripheral neuropathy
CU18162
Delta-2 tubulin biomarker enables CIPN diagnosis and targeted prevention/treatment, plus drug screening for prophylactic therapies.
Tags
Gene expression
Anticonvulsant
Biomarker
Inventors
Francesca Bartolini Ph.D.
Guido Cavaletti
Maria Elena Pero
Manager
Kristin Neuman
Departments
Pathology & Cell Biology
Divisions
College of Physicians and Surgeons (CUMC)
Columbia University Medical Center (CUMC)
Release Date
2019-07-15
Restoring synaptic function to prevent and treat neurodegenerative diseases
CU18018
Tech targets UBE3A to restore synaptic function, offering disease-modifying treatment for AD and other neurodegenerative disorders.
Tags
Gene expression
Amyloid beta
Enzyme
Inventors
Roger Lefort PhD
Manager
Kristin Neuman
Departments
Pathology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2019-01-25
Collections
CNS/Neurology
High-affinity RAGE fusion proteins for treating RAGE-mediated pathologies
Proxy35
RAGE fusion proteins selectively block RAGE-ligand interactions, potentially reducing oxidative stress and inflammation in multiple diseases.
Tags
Gene expression
Arteriosclerosis
Biological half-life
Inventors
Adnan Mjalli
Ann Marie Schmidt M.D.
David Mark Stern M.D.
Manager
Jerry Kokoshka
Departments
Dean's Office
Pathology
Surgery
Divisions
Columbia University Medical Center (CUMC)
Release Date
2018-10-20
Methods for diagnosis and treatment of neuropsychiatric disorders
2789
Genetic GCH1 assay guides diagnosis and personalized treatment for schizophrenia and related neuropsychiatric disorders.
Tags
Gene expression
Allele
Assay
Inventors
Catherine Clelland
Manager
Kristin Neuman
Departments
Pathology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2018-09-28
