Surgical imaging device for minimally invasive surgery2381An insertable, stereoscopic surgical imaging device enabling single-port, fully internal visualization with pan-tilt-zoom and lighting.TagsDepth perceptionLaparoscopyLensInventorsDennis FowlerPeter AllenManagerKristin NeumanDepartmentsSurgeryComputer ScienceDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-03-06
Colorectal cancer organoid model for therapeutic testingCU26010Patient-derived 3D colorectal cancer organoids enable precise drug screening, personalized therapy, and biomarker discovery.TagsColorectal cancerExtracellular matrixHigh-throughput screeningInventorsCasidhe-Nicole BethancourtDavid CohenJoel T. Gabre MDManagerJoan MartinezDepartmentsSurgeryHerbert Irving Comprehensive Cancer CenterMedicineDivisionsColumbia University Medical Center (CUMC)Release Date2025-10-09
Alcohol-free botanical oral care productsCU18267Alcohol-free, plant-based oral care formulations deliver rapid antimicrobial action, reducing side effects and environmental impact.TagsAnti-inflammatoryDental flossMedical deviceInventorsChathuranga De SilvaShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryChemical Engineering/Applied ChemistryDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-03-26CollectionsMedical Device
Natural botanical formulations with rapid and broad-spectrum antimicrobial propertiesCU12201Natural, alcohol-free plant-based antimicrobials delivering rapid, broad-spectrum protection for personal, veterinary, and cleaning uses.TagsAntibioticAntimicrobialDisinfectantInventorsHari Krishnan RamachandranLauserpina Algenio CaraosNayana BaijuManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2023-04-12
Non-irritating topical antimicrobial and skin disinfectant1506Non-irritating topical disinfectant using low-dose quaternary ammonium and essential oils for skin and mucous membranes.TagsAntimicrobialAntisepticCosmeticsInventorsMilind ShintreShanta M. ModakManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2020-02-10
Quat-free natural antimicrobial formulations for laundry sanitizersCU20079Botanical, quaternary-free fabric sanitizers delivering rapid, stable antimicrobial action for laundry and PPE disinfection.TagsAntimicrobialDisinfectantEscherichia coliInventorsChathuranga C. De SilvaShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryChemical Engineering/Applied ChemistryDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-07-18
Digital twin for cardiovascular surgery planningCU25246AI-driven patient-specific virtual heart surgery tool predicts post-operative blood flow to guide BLV treatment decisions.TagsAlgorithmCardiac surgeryCongenital heart defectInventorsDavid KalfaVijay VedulaYurui ChenManagerKristin NeumanDepartmentsSurgeryMechanical EngineeringDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-03-06
Preservation, rehabilitation, and storage of living allogenic heart valves capable of growth and self-repairCU23233Living, growth-capable heart valve biobank enables off-the-shelf, rehabilitated allografts with growth and self-repair potential.TagsAllotransplantationBiobankBioreactorInventorsDavid KalfaElizabeth CordovesGordana Vunjak-NovakovicManagerKristin NeumanDepartmentsSurgeryBiomedical EngineeringPathology & Cell BiologyDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-12-12CollectionsCardiovascular
Ring attachment for heart valve surgeryCU19219A flexible, suturing-free heart valve ring attachment that converts incomplete rings to complete, enhancing mitral/tricuspid repair.TagsHeart valveIon implantationMitral regurgitationInventorsShalaka Vinayak BapatVinayak N. BapatManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2024-05-27
Cell therapy methods for improved transplant acceptanceCU22264Hematopoietic stem cell therapy induces immune tolerance to transplanted organs, reducing rejection and long-term immunosuppression needs.TagsAllotransplantationCD34Cell therapyInventorsAubrey Marie SherryBrian H. JohnstoneDongsheng GuManagerJerry KokoshkaDepartmentsSurgeryMedicineDivisionsColumbia University Medical Center (CUMC)Release Date2024-09-05
Growing heart valve prosthesis that mitigates need for repeat surgeryCU20164Growing biohybrid pediatric heart valve that expands with the patient, reducing surgeries and healthcare costs.Tags3D printingArtificial heart valveCardiac surgeryInventorsDavid KalfaManagerKristin NeumanDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2021-01-05CollectionsMedical DeviceCardiovascular
Biofilm-resistance through durable polymeric coatingCU23387Durable botanical polymer coating prevents biofilm formation across surfaces, offering eco-friendly, long-lasting protection with optional silver.TagsAcneAntibioticAntimicrobialInventorsShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2025-01-13
Video-guided bedside thoracoscopy systemCU24084Video-guided bedside thoracoscopy enables safer, faster chest tube placement with real-time feedback and bedside diagnostics.TagsBiopsyCT scanChest tubeInventorsJosh SonnetMorgan MoroiRobert CrumManagerSara GusikDepartmentsSurgeryDivisionsCollege of Physicians and Surgeons (CUMC)Columbia University Medical Center (CUMC)Release Date2024-07-18
Electronic Illustrated Operative Notes (EION)CU24324A unified, illustrated cardiac operative notes platform streamlining EMR entries, standardizing procedures, and enabling cross-institutional data sharing.TagsCardiac surgeryCardiothoracic surgeryEHealthInventorsSyed Tasnim RazaManagerJoan MartinezDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2024-07-05
High-affinity RAGE fusion proteins for treating RAGE-mediated pathologiesProxy35RAGE fusion proteins selectively block RAGE-ligand interactions, potentially reducing oxidative stress and inflammation in multiple diseases.TagsArteriosclerosisBiological half-lifeCardiovascular diseaseInventorsAdnan MjalliAnn Marie Schmidt M.D.David Mark Stern M.D.ManagerJerry KokoshkaDepartmentsSurgeryDean's OfficePathologyDivisionsColumbia University Medical Center (CUMC)Release Date2018-10-20
Multilayered biocompatible and loadable bio-sealant for pulmonary air leaksCU17095Biocompatible, multilayer lung sealant combining ECM hydrogel and porous patch to seal pulmonary leaks and support healing.TagsExtracellular matrixGastrointestinal tractHydrogelInventorsBrandon GuenthartGordana Vunjak-NovakovicJinho KimManagerCynthia LangDepartmentsSurgeryBiomedical EngineeringMechanical EngineeringDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-02-15
In vivo internalizing RGD peptide production for enhanced treatment of solid tumorsCU25033In vivo iRGD plasmid drives tumor penetration, reducing immunosuppression; co-administers with CAR-T/ therapies for enhanced efficacy.TagsAngiogenesisCancer immunotherapyChemotherapyInventorsKazuki N. SugaharaNorio MiyamuraManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2025-11-20
Synergistic combination of botanical extracts and synthetics in an alcohol-free antimicrobial and disinfectantCU13067Alcohol-free antimicrobial blends botanical extracts with synthetic actives for quick, persistent germ-killing while preserving skin moisture.TagsAlcohol intoxicationAnti-inflammatoryAntimicrobialInventorsJaishree VaijanathappaSantoshkumar DongreShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2015-10-20
Rapid-deployment stapling system for aortic graft connectionCU25342A circular stapler rapidly connects vascular grafts to the aorta in seconds, reducing time, trauma, and bleeding risk.TagsAnastomosisAortaAortic aneurysmInventorsSyed Tasnim RazaManagerJoan MartinezDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2025-09-16
Therapeutic interventions for treating vascular malformationsCU20315Proteasome and PI3K/mTOR inhibitors target vascular malformations, enabling lower-dose, precise therapy with potential combinatorial options.TagsCell growthCombinatoricsEndotheliumInventorsAjit MuleyCarrie ShawberJune WuManagerCynthia LangDepartmentsSurgeryObstetrics & GynecologyDivisionsColumbia University Medical Center (CUMC)Release Date2023-01-24CollectionsRare Disease
Ring constructs and methods for improving outcomes in heart valve repair surgeryCU19218Adaptive, modular annuloplasty ring with adjustable rigidity and complete-to-incomplete ring conversion, improving valve repair outcomes.TagsHeart valveTricuspid valveInventorsShalaka Vinayak BapatVinayak N. BapatManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2020-02-14
Natural botanical formula for surface disinfectants and preservativesCU20129Botanical antimicrobial formula for safe, low-toxicity surface disinfectants and preservatives with strong efficacy.TagsAntimicrobialCosmeticsDisinfectantInventorsChathuranga C. De SilvaShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryChemical Engineering/Applied ChemistryDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-12-05
Facial moisturizer for peri and post menopausal womenCU24219All-in-one, cortisone-free facial moisturizer for peri/postmenopausal skin; reduces wrinkles, spots, dryness with natural botanicals.TagsAnti-aging movementAnti-inflammatoryMenopauseInventorsShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2024-05-29
Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs1926Intravenous omega-3 lipid emulsions post-ischemia protect and aid recovery across organs, enabling rapid EPA/DHA delivery.TagsAcute respiratory distress syndromeAngiographyBrain ischemiaInventorsRichard J. DeckelbaumYvon CarpentierManagerSara GusikDepartmentsSurgeryPediatricsDivisionsColumbia University Medical Center (CUMC)Release Date2010-04-16
Functional recovery of human donor lungs for transplantationCU13138Localized regional lung regeneration preserves vasculature to revive rejected donor lungs for transplantation.TagsDrug discoveryEx vivoExtracellular matrixInventorsDonald FreytesGopal SinghGordana Vunjak-NovakovicManagerCynthia LangDepartmentsSurgeryBiomedical EngineeringBiomedical InformaticsDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-11-20
Heart valve delivery system with rotational alignmentCU19063Rotationally aligned, fluoroscopy-guided transcatheter heart valve delivery ensures precise implant angles, reducing misalignment and complications.TagsAortic valveCirculatory systemFluoroscopyInventorsGilbert Hin Lung TangSusheel K. KodaliVinayak N. BapatManagerJerry KokoshkaDepartmentsSurgeryCardiologyCardiovascular SurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2020-12-24CollectionsMedical DeviceCardiovascular
Enhanced hemostatic dressing enables stabilization of traumatic hemorrhage2950Enhanced hemostatic dressing combines multiple factors to amplify coagulation, stabilize traumatic bleeding, and extend shelf-life.TagsBandageBleedingBody cavityInventorsGopal SinghMatthew BacchettaManagerSara GusikDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2015-10-09
Improved organ transplant preservation solution with modified albuminCU25173Modified albumin-based solution prevents glycation, extending organ preservation by maintaining structure and function.TagsAmino acidAnti-aging movementGlycationInventorsGiovanni FerrariManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2026-03-13
Growth-accommodating transcatheter-dilatable biostable prosthesisCU20095Expandable, sutureless transcatheter heart valve conduit that dilates noninvasively over time to accommodate patient growth.TagsAnticoagulantArtificial heartArtificial heart valveInventorsDavid KalfaJeffrey W. KysarRichard LiManagerDovina QuDepartmentsSurgeryMechanical EngineeringDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-10-23CollectionsMedical DeviceCardiovascular
Biocompatible polymer to prevent degeneration of bioprosthetic heart valvesCU20085Biocompatible polymer-coated bioprosthetic heart valves reduce serum protein uptake and AGE accumulation, slowing degeneration.TagsAdsorptionBiomaterialBovinaeInventorsAntonio FrascaGiovanni FerrariYingfei XueManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2020-12-24CollectionsMedical DeviceCardiovascular
Biomimetic composite patch for heart valve repairCU20173Biomimetic tri-layer polymer patch for durable heart valve repair, reducing degeneration and calcification while mimicking native tissue.TagsAortic valveBiomaterialBiomimeticsInventorsDavid KalfaMingze SunManagerKristin NeumanDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2020-12-02CollectionsCardiovascular
A natural antimicrobial and preservative agent to prevent microorganism growthCU14276Natural, chemical-free antimicrobial and preservative blend using organic molecules and oils for cosmetics, foods, and veterinary use.TagsAntimicrobialBacteriaCosmeticsInventorsArnab Kumar GhoshShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2014-07-07
Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs1895Omega-3 fish oil emulsion administered post-ischemia protects organs, reduces injury, and improves recovery in stroke and related conditions.TagsAcute respiratory distress syndromeAngiographyBrain ischemiaInventorsRichard J. DeckelbaumSusan J. VannucciYvon CarpentierManagerSara GusikDepartmentsSurgeryPediatricsDivisionsColumbia University Medical Center (CUMC)Release Date2010-04-16
Neovascularization inhibitor for tumor regression1897VEGF-targeting anti-angiogenic therapy halts tumor growth by starving tumors of blood vessels, promoting regression.TagsAngiogenesisBlood vesselCancerInventorsDarrell YamashiroGeorge YancopoulosJessica J. Kandel M.D.ManagerJerry KokoshkaDepartmentsSurgeryPediatricsDivisionsColumbia University Medical Center (CUMC)Release Date2009-12-01
Columbia openRPM flow meter design for respiratory profile monitoring systemsCU20304OpenRPM flow meter enables real-time ventilator flow/pressure monitoring; 3D-printed, autoclavable, standard tubing compatible.Tags3D printingAnatomical terms of locationAutoclaveInventorsAaron KyleDaniel SteingartGerard Agop AteshianManagerDovina QuDepartmentsSurgeryAnesthesiologyBiomedical EngineeringDivisionsColumbia University Medical Center (CUMC)Earth and Environmental EngineeringFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-04-13CollectionsMedical Device
Personalized and linkable clips for heart valve repairCU19133Customizable, linkable heart-valve clips (V-clips) enable personalized, non-invasive repair with multi-clip coupling and ventricular anchoring.TagsHeart valveMinimally invasive procedureMitral valveInventorsShalaka Vinayak BapatVinayak N. BapatManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2019-08-02CollectionsMedical DeviceCardiovascular
All-natural preservative formulation for perishable productsCU12112-aA natural, broad-spectrum preservative blend for cosmetics and personal care, reducing environmental impact and health concerns.TagsAntimicrobialCosmeticsPreservativeInventorsNayana BaijuSantoshkumar DongreShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2018-04-20
Hemostatic wound dressing with reduced clotting timeCU13372Flexible, biocompatible hemostatic dressing rapidly stops severe bleeding (under a minute), reducing clotting time and mortality.TagsAnalgesicAntihemorrhagicBiocompatibilityInventorsGopal SinghHarold CoonsJames M. SinclairManagerSara GusikDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2017-03-03
A non-irritating, effective botanical antimicrobial formulation for combating pathogensCU15074Alcohol-free botanical antimicrobial for oral care; non-irritating, broad-spectrum, effective against MRSA, C. albicans, S. mutans.TagsAntifungalAureusCandida albicansInventorsArnab Kumar GhoshShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2015-03-28
Visual aid tool for optimization of hospital resourcesCU20394A real-time bed map visualizes hospital resources and staffing to optimize surge capacity and patient throughput.TagsPandemicPatient safetyResource managementInventorsBeth HochmanManagerJoan MartinezDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2020-08-04CollectionsDigital Health (Software, AI, bioinformatics, etc)
Zinc salt composition for the prevention of mucosal and dermal irritation in healthcare workers1583A low-zinc topical additive reduces dermal/mucosal irritation while preserving antimicrobial efficacy for healthcare settings.TagsAntimicrobialContact dermatitisCosmeticsInventorsMilind ShintreShanta M. ModakTrupti GaonkarManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2019-01-31
07/01/2025CU25190Sacral nerve stimulation expands use to chronic pelvic floor disorders, offering potential relief beyond fecal incontinence.TagsBiofeedbackCentral nervous systemChronic painInventorsMarco Bertucci ZoccaliManagerJerry KokoshkaDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2025-05-01
Botanical formulation for rapid and natural acne treatmentCU19343A natural botanical topical gel rapidly treats acne, targets bacteria, reduces side effects, and works across cleansers and lotions.TagsAcidAcneCosmeticsInventorsChathuranga C. De SilvaShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryChemical Engineering/Applied ChemistryDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-01-02
Biventricular pacemaker for post-surgery heart pacing1372Adaptive perioperative biventricular pacemaker with real-time multiparameter optimization for personalized post-surgical cardiac pacing.TagsAlgorithmArtificial cardiac pacemakerBlood pressureInventorsHenry M. Spotnitz MDManagerSara GusikDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2018-12-07
Safe and effective antimicrobial made with essential oilsCU14083Botanical oil–based topical antimicrobial offers safe, broad-spectrum disinfection with reduced irritation for skin and surfaces.TagsAureusBiofilmCandida albicansInventorsArnab Kumar GhoshShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2018-04-20
Broad-spectrum natural preservativesCU15094Natural, odor-masking preservative blend of fruit acids, essential oils, and botanicals offering broad-spectrum antimicrobial protection.TagsAntimicrobialApple juiceDisinfectantInventorsLauserpina Algenio CaraosShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2018-04-07
Broad spectrum, natural antimicrobial preservative to battle bacterial contaminantsCU12112Natural, plant-based preservative with broad antimicrobial action, reduced irritation, compatible with cosmetics and medical products.TagsAntimicrobialCinnamonCosmeticsInventorsLauserpina Algenio CaraosNayana BaijuSantoshkumar DongreManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2014-07-07
All-natural mosquito repellent and anti-itch creamCU20052Botanical, non-DEET mosquito repellent and anti-itch cream; all-natural, non-steroidal, skin-friendly, safe for extended use.TagsCeramideCorticosteroidDEETInventorsChathuranga C. De SilvaShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryChemical Engineering/Applied ChemistryDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2019-08-19
All-in-one natural face cream for treating aging skin in peri- and post-menopausal womenCU23305All-natural, all-in-one botanical hydrogel cream reduces wrinkles, dryness, and dark spots without cortisone for peri- and post-menopausal skin.TagsAnti-inflammatoryDehydrationHuman skinInventorsShanta M. Modak Ph.D.ManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2023-11-03CollectionsWomen's Health
Topical, antimicrobial composition facilitates wound healing and prevents infections without causing irritation2466Broad-spectrum antimicrobial topical with anti-irritant, anti-inflammatory action, promoting wound healing and reducing infection risk.TagsAnti-inflammatoryAntimalarial medicationAntimicrobialInventorsLauserpina Algenio CaraosNayana BaijuShanta M. ModakManagerCynthia LangDepartmentsSurgeryDivisionsColumbia University Medical Center (CUMC)Release Date2014-09-22
